@micro_megs

PostDoc in @Guse_Lab 🦠🪸🔬 Fascinated by microbes, microscopy and bioinformatics. Lover of nature, music, art and hula hoops. @micro_megs@mstdn.science

 From Edmonton living in Munich
Joined June 2019
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Ecstatic to announce I have received a Marie Curie PostDoc Fellowship to work in the @Guse_Lab and understand how immunity regulates symbiosis in Aiptasia and corals. Thanks to @MSCActions for funding important research! 🧑‍🔬🪸 #Aiptasia
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We show that symbionts alter the expression of integrins and downstream signalling components in endodermal cells that take up symbionts, but not non-symbiotic algae.
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Finally, we over expressed the phagocytic RGD-binding integrins in HEK cells, which increased their capacity to phagocytose symbionts, but not non-symbionts. Mutation of the integrin binding site abolished the increase in phagocytosis.
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Together these data suggest RGD-binding integrins facilitate the uptake of symbionts but not non-symbiotic algae. Huge kudos goes out to @Mela_Doerr and all authors for these amazing insights. Integrins rock!
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🚨New @Guse_Lab Preprint Alert!🚨 Integrins are key receptors involved in the phagocytosis of symbionts in cnidarians. This sheds light on the mechanisms of symbiosis establishment in coral reefs. A thread... #coralreef #aiptasia #symbiosis biorxiv.org/content/10.1101/…

Symbiont-specific uptake is mediated by integrins in cnidarian larvae

The symbiotic relationship between dinoflagellate algae and their cnidarian hosts is fundamental to the health of coral reefs. The selection of appropriate symbionts is paramount for the host to gain...

biorxiv.org
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Meghan Ferguson retweeted
Ben Jenkins@realBenJen17 Sep 2024
Excited and proud to share our preprint! A network of glycan sensing controls endosymbiosis in the protist, Paramecium bursaria 🦠 This includes an ancient eukaryote immune-like factor, and prokaryote proteins acquired via horizontal gene-transfer! 1/10 doi.org/10.1101/2024.09.14.6…
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Meghan Ferguson retweeted
Guse Lab@Guse_Lab20 Jul 2024
We are hiring! guselab.de/_files/ugd/66d283…
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Meghan Ferguson retweeted
Guse Lab@Guse_Lab20 Jul 2024
We are also hiring a Postdoc! guselab.de/_files/ugd/66d283…
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Looking forward to another day of talks and meeting amazing researchers from around the world @Ecrs2024 🪸 If you want to chat about mechanisms behind symbiosis come find me today or at the poster session 3 tonight! #ECRS2024
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Today we start #ECRS2024 and I'm excited to meet the community and share my research in the @Guse_Lab on immune control of symbiosis establishment! Who else will I see there @Ecrs2024 ?
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Microscale sampling of the coral gastric cavity reveals a gut-like microbial community biorxiv.org/cgi/content/shor… #biorxiv_micrbio
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Ecstatic to see coral spawning for the first time in Okinawa these past couple days! And truly blessed to have the opportunity to run experiments with the larvae in the coming weeks! 🪸🔬🗾 @Guse_Lab #coralspawn #acropora
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Meghan Ferguson retweeted
Carly Scott@scottinthesea1 May 2024
Climate change is increasing the severity and frequency of coral bleaching globally... but why do corals even bleach in the first place? Check out our paper proposing a new hypothesis for why corals bleach. 🧵1/5 onlinelibrary.wiley.com/shar… @heatshok @AMOstling
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Research assistant position available in the UK with @Susie__McLaren using Aiptasia to study host-symbiont interactions during development 🥳jobs.cam.ac.uk/job/46073/
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Meghan Ferguson retweeted
Coral Morphologic@CoralMorph13 Feb 2024
Hi, Friends! We’ve just released 8 new CM photographic prints for sale in our web shop. Purchasing a print is a great way to beautify your home while supporting our efforts to research & restore Miami’s aquatic ecosystems: coralmorphologic.bigcartel.c…
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Officially been living in Munich for one year as of today! Been having a blast working on such an interesting model organism. Here's a pic of one of my CRISPR mutant Aiptasia polyps associated with symbionts (red) 😍 #aiptasia #mutant
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Meghan Ferguson retweeted
SymbNET@SymbNET18 Jan 2024
📣Interested in the dynamic relationship between hosts and microbes? Save the date for the "@SymbNET International Conference on Host-Microbe Symbiosis" in Algarve, Portugal 🗓️June 10-13! Keep an eye out for additional information coming your way soon. bit.ly/3v1Zcmm
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Getting back in the groove of things with my anemone friends after a relaxing break. Here's an image I captured lately of a juvenile Aiptasia polyp "kissing" a larvae 😍
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