The Mischel lab studies extrachromosomal oncogene amplification and altered metabolism in cancer. Account managed by lab members. Retweets are not endorsement.
Stanford, CA
Joined November 2019
- Tweets85
- Following325
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Mischel Lab retweeted
The eDyNAmiC team will investigate #ecDNA, found in around a third of cancers, hoping to develop much needed treatments for people whose cancer is driven in this way
Congratulations Paul Mischel (@mischellab @StanfordMed) and the team, funded by @CR_UK and @theNCI
3/n
Mischel Lab retweeted
It is very exciting to be part of the eDyNAmiC team to take the #CancerGrandChallenges and trackle cancer evolution driven by ecDNA. Thanks for the big support of @CancerGrand @QMULMaths @QMBCI
We are excited to share that the eDyNAmiC team has been chosen as a @CancerGrand, @theNCI & @CR_UK winner! #CancerGrandChallenges
Mischel Lab retweeted
Looking forward to working with @anton_gh, @michelle_monje, @huang_weini, @MariamJHanjani, @SihanSean, @BenjaminWerner_, @HowardYChang, @cbailey_58, @VineetBafna3, and many others.
We are excited to share that the eDyNAmiC team has been chosen as a @CancerGrand, @theNCI & @CR_UK winner! #CancerGrandChallenges
Mischel Lab retweeted
Congrats to my former colleague Junfeng Bi @mischellab for the new paper! He found that GBM, the most lethal brain tumor, is sensitive to SMPD1 inhibition. Adding antidepressant fluoxetine to standard-of-care chemotherapy can improve patient survival.
cell.com/cell-reports/fullte…
Mischel Lab retweeted
Excited to see this paper out. Joint work led by the @CalifanoMd and @VineetBafna3 labs. We characterized frequent human-HPV hybrid circular extrachromosomal DNA #ecDNA in HPV+ oropharyngeal cancer patients.
clincancerres.aacrjournals.o…
Mischel Lab retweeted
In uveal melanoma, PRC1 loss leads to gene de-repression, chromosome segregation errors, CIN, rupture-prone micronuclei & release of dsDNA into the cytosol, which activates the cGAS-STING pathway to induce inflammatory signalling & confers a poor prognosis nature.com/articles/s41467-0…
Mischel Lab retweeted
(1/2) Insights from #scRNAseq, coupled with fundamental #cell_biology, reveals loss of #PRC1 in a subset of tumor cells underlies transition of #uveal #melanoma from indolent to #metastatic phenotype. nature.com/articles/s41467-0… A team effort with @Samuel_Bakhoum @mischellab
Mischel Lab retweeted
Thankful for the outstanding mentorship I received from Paul Mischel @mischellab and colleagues @UCSDHealth.
And looking forward to making new friendships and collaborations @Yale.
New Haven, here we come!
4/4
Mischel Lab retweeted
Congratulations to Stanford Pathology Professor Paul Mischel @mischellab, PI for one of 11 teams shortlisted for the $25M #CancerGrandChallenges prize!
To find out more about their ecDNA project, visit: bit.ly/3iYaaBn
BREAKING NEWS: today we announce 11 teams selected to compete for our awards! Winners receive up to £20m each and the freedom to unleash their scientific creativity, conducting research that transcends geography and discipline - bit.ly/3cFyrZa #CancerGrandChallenges
Mischel Lab retweeted
Congratulations and good luck to Paul Mischel and his team @mischellab! They are working to understand the biology of extrachromosomal DNA generation and action, and developing new ways to target these mechanisms in #cancer.
BREAKING NEWS: today we announce 11 teams selected to compete for our awards! Winners receive up to £20m each and the freedom to unleash their scientific creativity, conducting research that transcends geography and discipline - bit.ly/3cFyrZa #CancerGrandChallenges
Mischel Lab retweeted
Congratulations to our Institute Scholar Paul Mischel @mischellab for leading one of the 11 teams shortlisted for the #CancerGrandChallenges $25M Prize!
Learn more about their ecDNA project here: bit.ly/3iYaaBn
BREAKING NEWS: today we announce 11 teams selected to compete for our awards! Winners receive up to £20m each and the freedom to unleash their scientific creativity, conducting research that transcends geography and discipline - bit.ly/3cFyrZa #CancerGrandChallenges
Mischel Lab retweeted
Congratulations to the 11 teams shortlisted for the next @CancerGrand Challenges awards! Each team now has a chance of receiving up to £20m to develop smarter, faster, and bolder ways to solve some of cancer’s toughest challenges: bit.ly/35gxCBO #CancerGrandChallenges
Mischel Lab retweeted
🔥🔥New preprint out! Led by @mischellab @BenjaminWerner_ @HowardYChang Vineet Bafna and Weini Huang.
We identified principles of ecDNA random inheritance and it’s consequences for cancer evolution
👇🏻👇🏻👇🏻 biorxiv.org/content/10.1101/…
Mischel Lab retweeted
While I am waiting for @jobRxiv to review my job ads, here is my lab's Github page to learn more about our research. And we are recruiting Postdocs! We have multiple positions opening right now!
github.com/sihanwusean/sihan…
Mischel Lab retweeted
Thank you @jobRxiv! Here is another portal to apply. We are hiring! Multiple postdocs positions opening now! If you are interested in extrachromosomal DNA in cancer, join us!
jobrxiv.org/job/childrens-me…
Mischel Lab retweeted
Come hear from our scientific founders, @mischellab @roelverhaak @HowardYChang, as they discuss in an educational session the importance of #ecDNA in cancer this Friday at #AACR21: businesswire.com/news/home/2…
Mischel Lab retweeted
The tweetorial for today's @Cancer_Cell paper. Extrachromosomal DNAs amplify oncogenes and oncogenic elements. @mischellab and @ScacheriLab have previously shown they consist of open chromatin, easily accessible to transcriptional machinery. cell.com/cancer-cell/fulltex….
Mischel Lab retweeted
Leading scientists come together to offer their insights into the role of extrachromosomal DNA in cancer.
With Roel Verhaak from @jacksonlab, Anton Henssen @MDC_Berlin and Paul Mischel from @Stanford School of Medicine, @melitairving
📆 24 May
rsm.ac/331CyJT
Mischel Lab retweeted
Check out this interesting piece in @TheScientistLLC exploring the links between cancer and extrachromosomal DNA (ecDNA) @mischellab @Stanford_ChEMH @StanfordMed @UCSanDiego @HowardYChang
- the-scientist.com/features/c…
#CancerResearch
Mischel Lab retweeted
Great overview about ecDNA by @mischellab ! Thank you for mentioning our work with @KHelmsauer @RichardKoche and @StefanMundlos ! I look forward to a lot of exciting discoveries on ecDNA in the next years with @mischellab @HowardYChang @roelverhaak and colleagues.
Excellent overview of the past, present, and potential future role of #ecDNA in cancer and therapy, from none other than Paul Mischel @mischellab! Thank you for the shout-out recognizing my work w/@anton_gh @ChariteBerlin and @sloan_kettering.
the-scientist.com/features/c…