openscience | studies, simplified retweeted
One of the week's most interesting papers.
☕️Filtered coffee -> slower biological aging.
☕️Instant coffee -> faster biological aging.
(screenshot from the Longevity Newsletter on @openscience_ink)
📰 THIS WEEK IN SCIENCE:
• Soda tied to faster biological aging
• GLP-1 discontinuation signals higher depression and anxiety risk
• $1 device delivers naked mRNA into skin—no lipid nanoparticles required.
What the studies actually found, and why they matter 👇
🍄 Psilocybin looked at beyond serotonin
• Researchers studied patients with depression in a randomized, placebo-controlled trial.
• Psilocybin selectively reduced two chemicals in cerebrospinal fluid: galanin and noradrenaline.
Why it matters: Most explanations of psilocybin begin and end with serotonin. These findings point toward another stress-signaling system—and give researchers measurable biomarkers to track.
📬For a weekly rundown of the latest studies in your topic of choice: openscience.ink
1/ Sleep duration shows a U-shaped relationship with biological aging across brain, body, and molecular systems.
A new paper analyzed sleep patterns and aging markers in 37-84 year olds using brain imaging, blood proteins, and metabolites.
A short thread:
4/ This wasn't just about the brain. Sleep duration connected to aging markers in organs throughout the body.
Shorter and longer sleep also predicted higher risks of depression, diabetes, and death over time.
5/ Interestingly, short and long sleep may lead to late-life depression through different pathways.
Long sleep appears to work partly through accelerated biological aging, while short sleep shows a more direct connection.
openscience.ink/paper/sleep-…
1/ Oil glands in your eyelids can get clogged, causing dry eye symptoms that make daily life uncomfortable.
A paper from 2023 tested whether combining radio waves with intense light therapy works better than light therapy alone.
A short thread:
5/ To see if radio waves added value, researchers compared their results to a previous study that used only light therapy plus gland expression.
The combination with radio waves showed larger improvements in gland function.
Symptom relief was similar between approaches.
6/ The comparison relied on historical controls rather than a direct head-to-head trial.
This limits how confidently we can attribute the extra benefit to radio frequency.
A randomized study would better isolate radio waves' specific contribution.
openscience.ink/paper/multi-…




