@rackham_chloe

Senior Lecturer in Diabetes, Islet Biologist, Mesenchymal Stromal Cell based strategies to improve Islet Function and Survival ❤️🚴🐱🌊🌿🎾

 Exeter, England
medicine.exeter.ac.uk/people/profile/index.php?web_id=Chloe_Rackham
Joined March 2019
  • Tweets134
  • Following455
  • Followers311
5Media
Kimberley Hansen the advocacy lead at @BT1D_CA talks about how living with #T1D is ‘wicked hard’ and we have to tell the story of the burden of life with #Type1Diabetes to our politicians
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Exciting project using multiplex immunofluorescence imaging, human islet-MSC/PSC co-culture, RNA-Seq, flow cytometry .jobs.ac.uk/job/DPX916/postdo…. Informal enquiries welcome 👍
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Interested in understanding the pancreas niche and therapeutic potential of pancreatic stellate cells (PSCs) and mesenchymal stromal cells (MSCs) in Type 1 Diabetes (T1D) prevention and treatment? Full time @The_MRC funded post-doc position available for 3 years from April 2026.
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Postdoctoral Research Associate opportunity at @UniofExeter, @Exeter_Diabetes Understanding the pancreas niche and therapeutic potential of PSCs and MSCs in Type 1 Diabetes T1D prevention and treatment. Apply here by 26th Jan 2026: jobs.ac.uk/job/DPX916/postdo…
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Human pancreatic #MesenchymalStromalCells express islet-protective ANXA1 and there are more MSCs around insulin-containing islets in #T1D. #MSC therapy may be most effective for individuals ≥13 years at diagnosis, where MSCs can better survive link.springer.com/article/10… 🔓
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Through Project Accelerate Cell Therapies, or Project ACT, Breakthrough T1D is pushing for the policies, funding, and access needed to bring manufactured cell therapies to the T1D community and make them available to everyone who needs them. Learn more here: bit.ly/3GWKzXA
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🔬 Th1nk Tank: Loss of β-Cell to δ-Cell Coupling & Impaired Glucagon Secretion in T1D 🧪 🎤 Thomas Hill, PhD (Oxford) 🗓️ Mar 27, 2025 | 12:00 PM EST 🌐 Register: us02web.zoom.us/meeting/regi… #DiabetesResearch #T1D #IsletBiology #BetaCells #DeltaCells #Glucagon #Hypoglycemia
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Excited to share our @R_DewhurstTrigg, @SarahIBEx @ngmorgan1, @Exeter_Diabetes, @UoEXCC, @ExeterBRC pre-print on BioRxiv doi: doi.org/10.1101/2025.03.05.6…. Characterisation of native human pancreatic mesenchymal stromal cells in type 1 diabetes.
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A huge thank you to @JDRFResearch, @DUK_research, @BT1DUK, @DiabetesnPOD for supporting our research
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Epic determination, hard work, scientific rigor and persistence with analysis pipelines/generation of huge human pancreaticMSC datasets from @R_DewhurstTrigg, a pleasure to work with such a passionate team of researchers on this @SarahIBEx @ngmorgan1 Martin Eichmann, Joss Atkins
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Chloe Rackham retweeted
Diabetes UK@DiabetesUK4 Feb 2025
🔬 We caught up with some of our #Type1DiabetesGrandChallenge researchers, who told us about the difference they hope their research can make to the lives of people living with #type1diabetes. 📽️ Watch the video and find out what they've said 👇 #GBDoc #Type1Diabetes #T1DX
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If you know of anyone living with Type 1 diabetes who would be happy to provide us with a blood sample in the morning and evening (can accommodate weekends too) you could really help us understand if the time of day could make a difference to how well therapies work!
Breakthrough T1D UK
@BT1DUK21 Jan 2025
Type 1 Diabetes Grand Challenge researchers need your help!🧑‍🔬 Researchers are looking for people aged 18-40 living with type 1 diabetes who can get to the University Hospital of Wales in Cardiff to give two blood samples over one day. This study looks to answer the question: Does timing matter for therapies to prevent beta cell destruction? This is so that the success of any future therapies for type 1 diabetes can be improved. To get involved in this study, please contact the research nurses Shinto Jose ([email protected]) and Alex Howell ([email protected]). Eligible participants who successfully donate two blood samples will get a £300 voucher for Love2shop ✨ Find out more: bit.ly/49w2flG @JAPearsonLab @cardiffuni #Type1DiabetesGrandChallenge #GBDoc
Promotional graphic for Type 1 Diabetes Grand Challenge research, inviting individuals aged 18-40 living with type 1 diabetes in Cardiff to participate. Includes the Type 1 Diabetes Grand Challenge logo and a photo of Dr. James Pearson on a blue and purple background.

ALT Promotional graphic for Type 1 Diabetes Grand Challenge research, inviting individuals aged 18-40 living with type 1 diabetes in Cardiff to participate. Includes the Type 1 Diabetes Grand Challenge logo and a photo of Dr. James Pearson on a blue and purple background.

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Congratulations @R_DewhurstTrigg and to all awardees. The future of T1D research is in great research hands and with the fantastic support from @BT1DUK 💙
Breakthrough T1D UK
@BT1DUK17 Dec 2024
We're funding four new UK research projects 💡 These exciting new studies are led by early career researchers with innovative ideas and will help accelerate life-changing breakthroughs to treat, prevent, and, ultimately, cure T1D and its complications. Learn more: breakthrought1d.org.uk/news/… #BreakthroughT1D #T1DResearch #T1D
A photo of Dr Mandeep Marwah at Aston University beside the words 'Dr Mandeep Marwah is developing a new type of dressing to help improve wound healing in T1D.'

ALT A photo of Dr Mandeep Marwah at Aston University beside the words 'Dr Mandeep Marwah is developing a new type of dressing to help improve wound healing in T1D.'

A photo of Dr Thomas Hill at University of Oxford beside the words 'Dr Thomas Hill is studying a type of pancreatic islet cell which he thinks could be targeted with a treatment to prevent hypos in T1D.'

ALT A photo of Dr Thomas Hill at University of Oxford beside the words 'Dr Thomas Hill is studying a type of pancreatic islet cell which he thinks could be targeted with a treatment to prevent hypos in T1D.'

A photo of Dr Rebecca Dewhurst-Trigg beside the words 'Dr Rebecca Dewhurst-Trigg is studying how islet helper cells may be involved in protecting insulin-making beta cells from immune attack in T1D.'

ALT A photo of Dr Rebecca Dewhurst-Trigg beside the words 'Dr Rebecca Dewhurst-Trigg is studying how islet helper cells may be involved in protecting insulin-making beta cells from immune attack in T1D.'

A photo of Dr Richard Pulsford at University of Exeter beside the words 'Dr Richard Pulsford is developing a simple visual tool to support people with T1D to exercise and reduce hypos.'

ALT A photo of Dr Richard Pulsford at University of Exeter beside the words 'Dr Richard Pulsford is developing a simple visual tool to support people with T1D to exercise and reduce hypos.'

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We're funding four new UK research projects 💡 These exciting new studies are led by early career researchers with innovative ideas and will help accelerate life-changing breakthroughs to treat, prevent, and, ultimately, cure T1D and its complications. Learn more: breakthrought1d.org.uk/news/… #BreakthroughT1D #T1DResearch #T1D
A photo of Dr Mandeep Marwah at Aston University beside the words 'Dr Mandeep Marwah is developing a new type of dressing to help improve wound healing in T1D.'

ALT A photo of Dr Mandeep Marwah at Aston University beside the words 'Dr Mandeep Marwah is developing a new type of dressing to help improve wound healing in T1D.'

A photo of Dr Thomas Hill at University of Oxford beside the words 'Dr Thomas Hill is studying a type of pancreatic islet cell which he thinks could be targeted with a treatment to prevent hypos in T1D.'

ALT A photo of Dr Thomas Hill at University of Oxford beside the words 'Dr Thomas Hill is studying a type of pancreatic islet cell which he thinks could be targeted with a treatment to prevent hypos in T1D.'

A photo of Dr Rebecca Dewhurst-Trigg beside the words 'Dr Rebecca Dewhurst-Trigg is studying how islet helper cells may be involved in protecting insulin-making beta cells from immune attack in T1D.'

ALT A photo of Dr Rebecca Dewhurst-Trigg beside the words 'Dr Rebecca Dewhurst-Trigg is studying how islet helper cells may be involved in protecting insulin-making beta cells from immune attack in T1D.'

A photo of Dr Richard Pulsford at University of Exeter beside the words 'Dr Richard Pulsford is developing a simple visual tool to support people with T1D to exercise and reduce hypos.'

ALT A photo of Dr Richard Pulsford at University of Exeter beside the words 'Dr Richard Pulsford is developing a simple visual tool to support people with T1D to exercise and reduce hypos.'

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Chloe Rackham retweeted
Carol Yang@YHCarolYang27 Nov 2024
The Yang lab will be expanding with MRC & Wellcome funding support! Watch out for recuitment adverts for technician, postdoc & PhD posts over the coming year. If you are interested in neural-pancreas interations, reach out for informal chats. #zebrafish #islet #diabetes
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We are hiring: a graduate research assistant and 2x postdocs for a diabetes project using advanced in vitro methods. Collab w/ @Thomaspiers and a cracking team of Co-Is GDRA: lnkd.in/eSwkfNHT PDRAx2: lnkd.in/efvA643b @ExeterMed #IPSC #Organoids #OOC
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Happy #internationalcatday2024 to all cats and their humans 😄 🥰
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Chloe Rackham retweeted
Nick Owens@nickdlowens6 Aug 2024
#JobAlert Computational #postdoc or #PhD on #singlecell #genomics understanding primate #GRNs involving KRAB ZNF ZNF808 in pancreas development: Paper: nature.com/articles/s41588-0… Job: tinyurl.com/mt3dv54m Applications will be reviewed 07/08/2024 but ad will stay open.
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Excited to share our latest research and a huge thank you to @DRWFwellness @JDRFResearch for their support @Exeter_Diabetes link.springer.com/article/10…

Mesenchymal stromal cells and their secretory products reduce the inflammatory crosstalk between...

Endocrine - Preculturing isolated islets with Mesenchymal Stromal Cells (MSCs) improves their functional survival in vitro and subsequent transplantation outcomes in vivo. The MSC secretory product...

link.springer.com
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