Curious scientist... Associate Professor @Sissaschool. Tweets are my own...
Joined February 2014
- Tweets359
- Following196
- Followers186
- Likes853
Remo Sanges retweeted
Transforming traditional views laid by “CNS immune privilege,” our research uncovers the brain’s purposeful presentation of self – that is the brain engages with the immune system through “guardian” peptides to ensure immune tolerance. @jonykipnis
nature.com/articles/s41586-0…
Remo Sanges retweeted
I'm excited to share with you the publication of my PhD/Postdoc project. A long journey with protagonist Foxg1, a transcription factor, and its new layer of gene expression regulation via the translational control, in neocortical neurons. Enjoy the read! bmcbiol.biomedcentral.com/ar…
Remo Sanges retweeted
How do enhancers work over distances that sometimes exceed megabases? Excited to share our work led by @gracecbower where we uncover a unique sequence signature globally associated with long-range enhancer-promoter interactions in developing limb buds: biorxiv.org/content/10.1101/… 1/
Remo Sanges retweeted
In the latest issues of Science, @ScienceTM, and @ScienceAdvances, the #PsychENCODE Consortium lay out findings based on examining human brains at the single-cell level. scim.ag/73Y (THREAD 🧵) #DecodingTheBrain
Remo Sanges retweeted
Sterile male release officially started on Procida Island!!! Thanks a lot to the Procida community and to the @fondaz_inf_act for the support and to the @2013_caa for the males production. Fingers crossed!!!
#unina #pnrr #nta #CitizenScience
Remo Sanges retweeted
Would you believe me if I told you that a single variant in a non-coding RNA explains ~0.5% of all undiagnosed individuals with neurodevelopmental disorders (NDD) in @GenomicsEngland ???
I didn’t initially either, but here is the story of RNU4-2 🧵1/9
Thrilled to share our latest discovery on a spliceosomal snRNA gene causing neurodevelopmental disorders: medrxiv.org/content/10.1101/… Thank you to everyone who contributed; it’s been a phenomenal effort to collaborate with clinicians and researchers for what would help many families!
Remo Sanges retweeted
This is so cool - a remarkably frequent mutation in a non-protein-coding RNA gene, which causes around one in every 200 currently undiagnosed cases of developmental delay around the world (including 8 Australian families so far!). A couple of thoughts (1/3)
Would you believe me if I told you that a single variant in a non-coding RNA explains ~0.5% of all undiagnosed individuals with neurodevelopmental disorders (NDD) in @GenomicsEngland ???
I didn’t initially either, but here is the story of RNU4-2 🧵1/9
Remo Sanges retweeted
Registration for free #Ensembl virtual workshops in May is now open:
⭐️#Genome browser: 7th to 9th May and ⭐️REST API from 14th to 16th May 2024 (14:00-17:00 BST).
Registration link in the blog post (bit.ly/4cW95DQ) #Ensembltraining #Bioinformatics
Remo Sanges retweeted
🗺️ Meet MapMyCells! 🗺️
Save time mapping gene expression data to reference taxonomies. Outputs incl. cell identity and confidence scores.
Now on Allen Brain Map, as latest addition to our Brain Knowledge Platform: portal.brain-map.org/atlases…
#studyBRAIN #SfN23
Remo Sanges retweeted
🔸 OPENING CEREMONY 2023 🔸
🎓 Today we celebrated the start of the 45th academic year at SISSA!
🫶 A huge thank you to everyone who joined us: your presence made it all the more special. Coming back to the Aula Magna "Paolo Budinich" after four years was like coming home.
Remo Sanges retweeted
New paper from our lab - LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification @ScienceAdvances @Lund_Stem 🧬
science.org/doi/full/10.1126…
Remo Sanges retweeted
Yes new independent evidence that translation can be positively modulates by antisense RNAs, containing some effector domain like SINEUPs or IRES. Good to see independent labs developing variants of our technologies!
Pleased to see the principles described in “Internal Ribosome Entry Site sequences act as Effector Domain in linear and circular antisense long non-coding SINEUP RNA” biorxiv.org/content/10.1101/… are independently validated in nature.com/articles/s41467-0… SINEUP technology works worldwide!
Remo Sanges retweeted
Pleased to see the principles described in “Internal Ribosome Entry Site sequences act as Effector Domain in linear and circular antisense long non-coding SINEUP RNA” biorxiv.org/content/10.1101/… are independently validated in nature.com/articles/s41467-0… SINEUP technology works worldwide!
Remo Sanges retweeted
DNA methylation is linked to the monoallelic expression of MRP3, a diatom mating type determining gene dlvr.it/SxKKG7
Remo Sanges retweeted
Are promoters just landing pads for the transcriptional machinery? No! They can be key regulatory centers during development. Vivek Ramalingam shows this in some beautiful new work published in @NatureComms.
Thread below: (1/6)
doi.org/10.1038/s41467-023-4…
Remo Sanges retweeted
Excited to share our latest preprint, led by @GiuliaPasquesi , on transposons and interferon signaling! 👇 for a 🧵 on cryptic splice variants, decoy receptors, and viruses (1/N)
Regulation of interferon signaling by transposon exonization biorxiv.org/cgi/content/shor… #biorxiv_genomic
Remo Sanges retweeted
I wrote a brief explainer about genetics and race/ethnicity; how they are not really related as much as many people think and why this is important to discuss in the modern world. linkedin.com/pulse/ethnicity…
Remo Sanges retweeted
Check out our new page dedicated to #RNAjobs
👉iit.it/en-US/web/irna/openin…
Feel free to RT "ad libitum"
@jrRNAscientists @TheRNAInstitute @RTI_UMassChan @umichrna @YaleRNA @DukeRNAcenter @TrentoRNASalon @HKRNAClub @JenaRNAClub @EMBO @embl @EMBLRome @humantechnopole
Remo Sanges retweeted
Zenbu-Reports is published and available: academic.oup.com/nargab/arti…
Zenbu (that in Japanese means "everything") allow you to custom-visualize your data, without extensive programming.
Remo Sanges retweeted
Join us in shaping the future of #genomics research at @humantechnopole! We're hiring a #Bioinformatician for our Functional Genomics Computation Unit.
Apply before 15 Sep 👉 careers.humantechnopole.it/o…