Rob Mahen (@robmahen) header
Rob Mahen (@robmahen) profile picture

Rob Mahen

@robmahen

Cells, centrosomes, cilia. Lecturer and PI at @uniofleicester. Previously @Cambridge_Uni @imperialcollege @EMBL . Not the views of my employer.

 Leicester, Cambridge, UK
le.ac.uk/people/robert-mahen
Joined March 2014
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Photo by Rob Mahen (@robmahen)Photo by Rob Mahen (@robmahen)Photo by Rob Mahen (@robmahen)Photo by Rob Mahen (@robmahen)Photo by Rob Mahen (@robmahen)Photo by Rob Mahen (@robmahen)Photo by Rob Mahen (@robmahen)Photo by Rob Mahen (@robmahen)Photo by Rob Mahen (@robmahen)Photo by Rob Mahen (@robmahen)
Woohoo! "A guide to single particle tracking" is now online! Together with @Francois__Simon & @S_vanTeeffelen, we share our thoughts on going beyond MSD analysis in Nature Reviews Methods Primers. doi.org/10.1038/s43586-024-0… Free read link: rdcu.be/dTKHd
Image from Lucien Weiss (@LucienWeissLab)
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A wonderful tribute to a truly exceptional scientist, teacher, supervisor and person. journals.biologists.com/jcs/…
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Is there anyone credible out there can explain in simple terms why this isn’t a truly terrifying image? Like, why isn’t this headline news almost every day?
Image from Ben Goldsmith (@BenGoldsmith)
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Happy #FluorescenceFriday! Just a little ol' Fluo cell, imaged by confocal. Not trying to do too much, very demure, very mindful.
Image from Vanderbilt Cell Imaging Shared Resource (@VUCellImaging)
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What a week! Anyone else possibly discover signs of microbial life from billions of years ago on a planet 140 million miles from Earth? No? Just me?
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The nucleus of a human cell, as worked on by various groups in @LeicesterMCB @LeicStructBio
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Incredible and terrifying. Can we please all open our eyes? 👀
Prof. Eliot Jacobson (@EliotJacobson) profile pictureProf. Eliot Jacobson
@EliotJacobson8 Mar 2024
Breaking news! Code FUBAR!!! Well, today is the day I have to extend the y-axis to accommodate a new record Global sea surface temperature of 21.21C. How is your day going?
Image from Prof. Eliot Jacobson (@EliotJacobson)
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Looking for a #postdoc or #PhD in eukaryotic #DNA replication and #CryoEM? We are recruiting! The positions are fully-funded by the @novonordiskfond and come with access to cutting-edge facilities and fantastic colleagues in #Copenhagen. See links below for more information.
Image from Thomas Miller (@TCR_Miller)
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FlexSIM reconstruction of actin network (gray), microtubules (red), and clathrin (blue) in COS- 7 cells imaged in TIRF-SIM mode. #FluorescenceFriday
Image from Emmanuel Soubies (@EmmanuelSoubies)
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Rob Mahen retweeted
Ed Hollox (@edhollox) profile picture
Ed Hollox@edhollox13 Nov 2023
Please retweet! I am second supervisor on this very interesting BBSRC-funded PhD project with structural biologist Dr Rob Mahen @uniofleicester . Structure of the cilia centrosome meets genetic variation. You will get to use some seriously cool kit! warwick.ac.uk/fac/cross_fac/…
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Happy to share this PhD opportunity as co-supervisor studying bovine preimplantation embryo viability. December 31st application deadline and the position can be taken up with a flexible start date as early as January next year @CGM_NCL @nubiosciences findaphd.com/phds/project/ph…
PhD studentship in Animal Reproduction: Development of in vitro techniques to explore bovine...

PhD studentship in Animal Reproduction: Development of in vitro techniques to explore bovine...

PhD Project - PhD studentship in Animal Reproduction: Development of in vitro techniques to explore bovine preimplantation embryo viability at Newcastle University, listed on FindAPhD.com

findaphd.com
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Rob Mahen retweeted
preLights (@preLights) profile picture
preLights@preLights3 Mar 2023
Unclearing microscopy: seeing human cells directly by eye. 👀 Two more #preLights are now online! @robmahen highlights an amazing #preprint from @OnsMSaad1, @mshribak & @bewersdorflab which introduces a promising new technique: #UnclearingMicroscopy 👉 prelights.biologists.com/hig…
Metallic silver (c) and DAB (d) uncleared HeLa cells on a glass bottom dish, imaged with a cell phone camera. e, f, Magnified views of the areas outlined by the black and brown boxes in c and d, respectively.

ALT Metallic silver (c) and DAB (d) uncleared HeLa cells on a glass bottom dish, imaged with a cell phone camera. e, f, Magnified views of the areas outlined by the black and brown boxes in c and d, respectively.

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How is "#centrosome cohesion" between two centrioles maintained during interphase?@robmahen combines live cell quant imaging, U-ExM & ectopic tethering to explore how cNap1 helps #centrioles maintain spatial proximity inside human cells #PLOSBiology plos.io/3VYc6Lr
Image from PLOS Biology (@PLOSBiology)
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Galaxies collide in Stephan’s Quintet, pulling and stretching each other in a gravitational dance. In the mid-infrared view here, see how Webb pierces through dust, giving new insight into how interactions like these may have driven galaxy evolution in the early universe.
Stephan’s Quintet, a collection of five galaxies, as seen by MIRI on the James Webb Space Telescope. The galaxies all glow in different colors, surrounded by lacy, glowing clouds of gas and dust. Four of the five are centered in the image. Three are visibly spiral galaxies, with tendrils extending out from their glowing centers. The galaxy farthest to the left appears slightly more clearly, with vibrant blue lacing surrounding the oval-shaped light of the galaxy. This is because the farthest left galaxy is not interacting with the other four; it’s actually far in the foreground from the others. The galaxies all appear against a field of sparkling stars and other, farther galaxies.

ALT Stephan’s Quintet, a collection of five galaxies, as seen by MIRI on the James Webb Space Telescope. The galaxies all glow in different colors, surrounded by lacy, glowing clouds of gas and dust. Four of the five are centered in the image. Three are visibly spiral galaxies, with tendrils extending out from their glowing centers. The galaxy farthest to the left appears slightly more clearly, with vibrant blue lacing surrounding the oval-shaped light of the galaxy. This is because the farthest left galaxy is not interacting with the other four; it’s actually far in the foreground from the others. The galaxies all appear against a field of sparkling stars and other, farther galaxies.

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Typical. A decade of posting thoughtful comments about #genomics goes largely unnoticed. But you send ONE cat tweet....
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Your front-row seat to my Mars landing is here. Watch how we did it. #CountdownToMars

Perseverance Rover’s Descent and Touchdown on Mars

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Hello, world. My first look at my forever home. #CountdownToMars
Image from ARCHIVED - NASA's Perseverance Mars Rover (@NASAPersevere)
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A great sketch of how we could do science better: worksinprogress.co/issue/the… Unfortunately mostly about the easy (!) problem of updating how science is practised, and less about the hard but key problem of how to set up incentives and institutions that enable the update.
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“Phase separation” looked like a groundbreaking idea, and pharma giants opened their wallets. A hypothetical soon became established dogma. Then, skeptics arrived claiming shoddy science. fcld.ly/eght3jl #LongReads
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Rob Mahen retweeted
preLights (@preLights) profile picture
preLights@preLights31 Dec 2020
@robmahen wrote about the SARS-CoV-2-Human Protein-Protein Interaction Map 5/8 prelights.biologists.com/hig…
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