#KidneyWk 👉🏻Rethinking post-AKI care! 🏥 COPE-AKI trial: Can multidisciplinary care improve recovery after severe AKI? 👩‍⚕️ Nurse navigator + pharmacist + nephrologist + remote monitoring 🎯: hospital-free days at 90 days. Kidney recovery needs team-based care beyond discharge!

#KidneyWk 2026 | Post-AKI care: One size does NOT fit all! KAMPS provides a framework: 🩺 Kidney function 📢 Advocacy 💊 Medications 🩸 Pressure ⚠️ Sick-day rules 💡 Recovery care must be individualized by AKI etiology, comorbidities & medication needs.

#KidneyWk 2026 | Closing the post-AKI care gap 📊 AKI documentation at discharge improved from 22% to 92% with bundled intervention. ⚠️ Yet fewer than 25% receive🫘 function testing within 90 days. AKI recovery requires structured follow-up, better ℹ️ & multidisciplinary care!

#KidneyWk 2026 | Moving from AKI recognition to prevention! 📊 Tackling AKI: Better care, shorter hospital stays, but no mortality benefit. 💊 NINJA: 23.8% reduction in nephrotoxic AKI across centers. 💡 The future of AKI prevention lies in system-level interventions!

#KidneyWk 2026 | AKI care gaps ⚠️ Patient education and post-AKI follow-up remain inadequate. 4️⃣ priorities: 1️⃣ Early recognition 2️⃣ Better discharge communication 3️⃣ Structured follow-up 4️⃣ Global implementation (ISN 0by25 & 5R) AKI care must extend beyond hospital discharge

#KidneyWk 2026 Key predictors of successful dialysis discontinuation: 💧 Higher urine output 📊 Creatinine clearance ≥10 mL/min (stronger signal at 15–20) 🧪 UACR for assessing kidney recovery potential Simple clinical tools remain essential for individualized RRT decisions.

🔬 #KidneyWk 2026 | Biomarkers in AKI Urinary CCL14 outperformed NGAL, CHI3L1, cystatin C & proenkephalin in predicting persistent severe AKI. 📊 Higher CCL14 levels were linked to greater RRT requirements. CCL14 may improve risk stratification and guide kidney care decisions.

🔬 #KidneyWk 2026 Beyond urine output & CrCl, proenkephalin (penKid) may help predict kidney recovery. 📊 ELAIN analysis: Lower pre-RRT penKid predicted earlier successful dialysis liberation. 💡 Biomarkers + functional assessment may guide personalized RRT discontinuation.

🔬 #KidneyWk 2026 | Urine microscopy is valuable for AKI diagnosis, but its role in guiding RRT discontinuation remains unvalidated. ⚠️ Operator dependence & unreliable urine chemistry limit its use. Diagnostic utility ≠ predictive value for 🫘recovery.

Pre-admission proteinuria is a key predictor of renal non-recovery! In patients with baseline eGFR 15–29, 90-day kidney recovery declined from 45.5% to 25.3% with ≥2+ proteinuria. AKI recovery depends not only on injury severity, but also on pre-existing 🫘health. #KidneyWk

Can the furosemide stress test predict 🫘 recovery after CRRT? In 25 patients, urine output after IV furosemide was significantly ⬆️in those who recovered 🫘function (654 vs 48 mL; AUC 0.84). A promising functional tool to guide RRT liberation, beyond serum sCr alone. #KidneyWk

A paradigm shift in AKI-D management #KidneyWk The LIBERATE-D study challenges the idea that 🫘 function must recover before stopping dialysis. Even with CrCl of 5–<10 mL/min, 44% remained dialysis-free for 7 days. Could stopping dialysis be part of the path to kidney recovery?

🧬 From the RNA world to complex life! At #KidneyWk 2026, Craig Mello explores how biological information evolved—from RNA & DNA to intricate networks of molecular interactions. Life’s information is not just encoded in genes; it emerges from dynamic, self-organizing networks.

🧬 Identical transgenes at the same chromosomal site can remain ON or OFF through stable gene silencing. A striking example of RNA-mediated epigenetic regulation—and its potential to inspire precision therapies! 🔬#KidneyWk

🧬 At #KidneyWk 2026, Craig Mello highlights RNAi’s therapeutic power: synthetic siRNAs guide Argonaute (RISC) to complementary mRNAs, triggering their degradation and reducing disease-causing protein production. Precision medicine at the RNA level! 🔬

🧬 From C. elegans to precision medicine At #KidneyWk 2026, Craig Mello highlights how RNAi transformed basic science into targeted therapeutics. The breakthrough: silencing disease-causing genes at the mRNA level, opening new avenues for treating previously undruggable targets

Inspiring start to Day 3 of #KidneyWk 2026! Listening to Nobel Laureate Craig C. Mello on RNA interference, from discoveries in C. elegans to a revolution in molecular biology and medicine. A powerful reminder of how basic science transforms human health! 🔬🧬

Proud to see my mentor, Prof. @RavindraLMehta1, receive the prestigious @ASNKidney 2026 Robert G. Narins Award at #KidneyWk! As a former mentee, I am deeply grateful for his guidance, inspiration, and lasting impact on my professional journey. Well-deserved recognition, Ravi!

🏃‍♂️ Second @NephJC morning run in Denver before Day 3 of #KidneyWk 2026! This time led by @kidney_boy! 🌄🏔️ Great way to start the day with friends, exercise, and the amazing nephrology community! @NephJC @ASNKidney #NephRun #KidneyWk