@sandykilla

🅞🅡🅖🅐🅝🅞🅜🅔🅣🅐🅛🅛🅘🅒🅢... Lecturer in Inorganic Chemistry at @UniofLeicester @LeicesterChem

 Leicester, England
Kilpatrickgroup.uk
Joined March 2011
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🧪⚡️♻️ Exciting #PhDchat opportunity! Join our group @Leicesterchem on project 2026-L05 "Closing the Loop: Sustainable Catalysts and Solvents for CO2 Valorisation" with @_PatriRM via @CENTA_NERC. centa.ac.uk/studentship/2026… Informal enquiries welcome.
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🚨 I’m looking for a keen PhD student to join my group at @Leicesterchem as a Graduate Teaching Assistant (GTA). Project on Ti complexes for CO2 valorisation & sustainable materials. #organometallics #catalysis Full training provided. Deadline 22 June 2026 le.ac.uk/study/research-degr…
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Eminemi's preprint now online: Deep Eutectic Solvents as Recyclable Media for Metal Removal from Crude Oil | ChemRxiv - go.shr.lc/4pjURT4

Deep Eutectic Solvents as Recyclable Media for Metal Removal from Crude Oil | ChemRxiv

Crude oil contains trace metal species that impair refinery performance, poison catalysts, and contribute to environmental contamination. Conventional metal-removal processes, such as hydrotreating...

chemrxiv.org
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Jamie’s paper on bulky [S,N] Zinc catalysts for aldehyde hydrosilylation just published in #ZAAC 👉doi.org/10.1002/zaac.2025001… Fantastic teamwork from computational maestro @TobiKraemer + new collaborator Sam Gaughan - a pleasure to work with!

Aldehyde Hydrosilylation with Ethylzinc Complexes of Bulky β‐Thioketiminate Ligands

A sterically demanding β-thioketiminate ligand supports a monomeric ethylzinc complex that catalyses aldehyde hydrosilylation with phenylsilane (PhSiH3). In the presence of methanol (MeOH), high...

onlinelibrary.wiley.com
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@Leicesterchem Ranked 2nd in UK 🥈🇬🇧… that's 1st in England 🥇🏴󠁧󠁢󠁥󠁮󠁧󠁿 -  @guardian University Guide 2026 - Universities ranked by subject area: Chemistry theguardian.com/education/ng…
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Olympia & Ginevra’s paper “Anti-Breast Cancer Stem Cell Activity of Titanocene Complexes of NSAIDs” is out in @DaltonTrans 👉doi.org/10.1039/D5DT01491C A tidy @Leicesterchem collab: titanocene synthesis in our lab & biology from @_Suntharalingam group — a great friend & colleague
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We report two new titanocene–NSAID complexes that show: 🔹 strong activity against breast CSCs, with one rivaling cisplatin & salinomycin 🔹 improved safety when delivered via nanoparticle encapsulation This is the first study to explore #titanocenes in anti-CSC therapy.
Titanocene(IV)-NSAID complexes Cp2Ti(mefenamate)2 (4) and Cp2Ti(flufenamate)2 (5) show enhanced redox stability and potent cytotoxicity against breast cancer stem cells (CSCs), with 5 rivaling salinomycin and cisplatin. Complex 5 induces DNA damage and apoptosis, and its nanoparticle encapsulation improves biocompatibility. This is the first report targeting breast CSCs with titanocene-based metallodrugs.

ALT Titanocene(IV)-NSAID complexes Cp2Ti(mefenamate)2 (4) and Cp2Ti(flufenamate)2 (5) show enhanced redox stability and potent cytotoxicity against breast cancer stem cells (CSCs), with 5 rivaling salinomycin and cisplatin. Complex 5 induces DNA damage and apoptosis, and its nanoparticle encapsulation improves biocompatibility. This is the first report targeting breast CSCs with titanocene-based metallodrugs.

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This application is a bit of a departure for our group, but the idea was sparked after my mum’s breast cancer diagnosis (incl. chemo, tho not titanocenes!). She is thankfully doing much better now. Very rewarding to see our former MChem 🌟Olympia drive this project to publication
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Olympia & Ginevra’s preprint now online… Anti-Breast Cancer Stem Cell Activity of Titanocene Complexes of Non-Steroidal Anti-Inflammatory Drugs | ChemRxiv - go.shr.lc/4dLU8EX

Anti-Breast Cancer Stem Cell Activity of Titanocene Complexes of Non-Steroidal Anti-Inflammatory...

Titanocene(IV)-NSAID complexes Cp2Ti(mefenamate)2 (4) and Cp2Ti(flufenamate)2 (5) show enhanced redox stability and potent cytotoxicity against breast cancer stem cells (CSCs), with 5 rivaling...

chemrxiv.org
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Thanks to alumni, staff & friends returning to @uniofleicester today to celebrate our @Leicesterchem Centenary… a day of fantastic demos, culinary experiments and keynote talks 💯
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Enjoyed my visit to sunny @UniofReading today for chemistry dept seminar to share our latest work on bimetallic catalysis. Thanks to @DrJamesHallett for the kind invitation and colleagues for interesting discussions!
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Glorious weather for our #OfferHolderDay today... meeting future @Leicesterchem students a great reminder why we do it!
University of Leicester@uniofleicester12 Apr 2025
🎯Leicester is alive with energy! ⚡Future students are touring campus, meeting current students and seeing where the next few years could take them. 👀Here’s a look at the action so far. 📍Tours every 45 mins – Centenary Square. #CitizensOfChange #TakeYourPlace #OfferHolderDay
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Can't get access to any subscription-based @ACSPublications articles 😱 ... this a @Uniofleicester Library thing?
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....aaand we're back!
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Latest paper by Jamie Allen et al. is now published in @Orgmet_ACS doi.org/10.1021/acs.organome… … a good chunk of Jamie's PhD has been dedicated to the organozinc #synthesis and #catalysis explored in this work... 📄✨
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Beautiful structures which are dimeric in the solid state #XRD but monomers in solution by DOSY #NMR. The active catalyst has proven a rather slippery customer thus far 🔥 but we think the hydroboration reaction is accelerated by trace water... 🧯💦
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First paper with @TobiKraemer @tcdDublin whose expert #DFT calcs unveiled a plausible mechanism for catalytic hydroboration via a zinc hydride intermediate. ⚙️📈 Looking forward to many more exciting collaborations ahead! #experimental 🤝 #computational
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Team Chemistry looking forward to meeting future @LeicesterChem students at our #OfferHolderDay @uniofleicester today! #MeetYourTutors
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Happy Boxing Day #preprint from Jamie Allen et al. doi.org/10.26434/chemrxiv-20… … feels a bit like unwrapping next year’s presents early 🎁

Organozinc β-thioketiminate complexes and their application in ketone hydroboration catalysis |...

The [S,N] chelating ligand 1 ([HC{C(Me)(Ndipp)}{C(Me)(S)}]−, dipp = 2,6-diisopropylphenyl) was used to prepare a series of novel organozinc complexes [RZn-1], with R = Et (2), Ph (3), C6F5 (4)....

chemrxiv.org
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