Clinical Pathologist. Synthetic Biologist. 🏳️🌈
Boston, MA
Joined July 2013
- Tweets132
- Following375
- Followers273
- Likes710
Come find me here! Getting rid of this account. bsky.app/profile/scientistja…
Incredibly proud of my super smart friend!!
Super excited to receive an @NIHDirector’s Early Independence Award! Thank you @NIH_CommonFund for supporting our work to identify convergent mechanisms of neurodevelopmental disease @BCMFromtheLabs @TCHResearchNews
#NIHHighRisk
I like this post! More cell free synthesis of bacteriophage and virus please! pubs.acs.org/doi/10.1021/acs…
A fantastic team to join!!
Come join our team! We are hiring a clinical coordinator to help facilitate our biobanking initiative @TexasChildrens. The coordinator will play a critical role in enrolling patients, interfacing with the clinical team, & managing specimens.
jobs.bcm.edu/job/Houston-Res…
Please RT!
James DiCarlo, MD, PhD retweeted
Happy National Doctors Day. Physicians as well as Dentists are doctors as they botth undergo extensive medical training. Also, @umdentistry believes in Medical-Dental Integration. @UMBaltimore @FnnngPatricia @ADANews
Happy National Doctors Day to all of our current and future doctors at UMB! #WeAreUMB #UMBtogether #NationalDoctorsDay
James DiCarlo, MD, PhD retweeted
Although a recent high-profile paper claimed that synonymous mutations could be just as important as nonsynonymous ones in causing human disease, we argue that synonymous mutations are predominantly neutral in our new @AJHGNews Commentary
authors.elsevier.com/a/1gAt-…
James DiCarlo, MD, PhD retweeted
In their @Nature paper, Shen et al report that synonymous variants are just as deleterious as nonsynonymous variants. In our new preprint, we caution against interpreting this study in the context of human disease
biorxiv.org/cgi/content/shor…
@dgmacarthur @mehurles @SlavePetrovski
This is a awesome opportunity to work on cutting edge science with incredible mentors!
Please RT! We are hiring a new technician to work on CRISPR screens in stem cell derived neurons to understand the molecular basis of autism and intellectual disability. You will be co-mentored by me and Dr. Huda Zoghbi! @bcmhouston
jobs.bcm.edu/job/Houston-Res…
James DiCarlo, MD, PhD retweeted
Great presentation by @scientistjames and team, a previous @CivilizationVC fellow, at @NucleateHQ Boston's pitch competition. Maybe some future therapeutic starting material is hiding in our backyards...#abugslife
Congrats to @hhlee and the team at @CultivariumFRO !! Very excited to see what is ahead.
A dream 8 years in the making, both the subject matter and a new model of science. Excited to be on this path with @AdamMarblestone, @AGamick, @SchmidtFutures. LET’S DO THIS.
Its possible that plant-derived extracellular vesicles represent a paradigm shift in how we think about engineering therapeutics. Think about how much cheaper RNA therapies would be if they grew on trees. #RNA #GeneTherapy sciencedirect.com/science/ar…
Calling all scientists who want to advance de-extinction science and allow for a brighter future for all species - extinct and extant.
Join the Woolly Mammoth team at Harvard's @geochurch Lab! We are pleased to share a new post-doctoral fellowship opportunity for well-qualified individuals. Learn more: reviverestore.org/woolly-fel…
A foundational advance for the treatment of pain disorders. Fantastic work @prashantgmali and colleagues.
Led by the amazing Ana Moreno and via a wonderful long-term collaboration with Tony Yaksh.
Long-lasting analgesia via targeted in situ repression of NaV1.7 in mice stm.sciencemag.org/content/1…
James DiCarlo, MD, PhD retweeted
Check out the inaugural Clinical Pathology Case of the Month @BWHPath from @scientistjames! #pathology
#BWHPathCPCotM
Older man with history of B cell lymphoma admitted for induction chemotherapy.
What is going on with this patient’s potassium?
#Pathology #LabMed
1/
James DiCarlo, MD, PhD retweeted
A deep learning method to prioritise non-coding regions of the genome using intolerance to variation and sequence context.
@dimvitsios @RyanDhindsa @ayalgussow @SlavePetrovski
nature.com/articles/s41467-0…
James DiCarlo, MD, PhD retweeted
Very excited to share our analysis of exome sequencing data from 200K participants in the @uk_biobank. @AstraZeneca @kerencarss @DrAndrewHarper @ruth_march #SlavePetrovski
biorxiv.org/content/10.1101/…
James DiCarlo, MD, PhD retweeted
Happy to see our manuscript, "A transcriptome‐based drug discovery paradigm for neurodevelopmental disorders" now published in Annals of Neurology!
onlinelibrary.wiley.com/doi/…
@awzoghbi @c_vasavda @GoldsteinDB
Our latest manuscript, "Establishing a transcriptome-based drug discovery paradigm for neurodevelopmental disorders" is now on @biorxivpreprint.
biorxiv.org/content/10.1101/…
James DiCarlo, MD, PhD retweeted
BREAKING NEWS:
The 2020 #NobelPrize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”
James DiCarlo, MD, PhD retweeted
We have a lab opening for a Technician position immediately. Will be involved in w/ cutting edge research in gut microbiome, engineering, cultivation, etc. Please RT!
opportunities.columbia.edu/c…