MD/PhD candidate @uOttawa. Full-time student of 🧠 and ⚕️, part-time student of 🚴 and 🐈
Joined July 2022
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Sébastien Maillé retweeted
Research is essential to the health, prosperity and security of Canada.
Canadian researchers have a long history of achievement.
Investment in researchers, postdocs and grad students means new discoveries-treatments, climate solutions, technologies, and a better future for all.
Sébastien Maillé retweeted
Interested in short-term plasticity? Our recent findings have just been published! With @Neuronaud @mossy_fibers @j_rossbroich
Online: cell.com/cell-reports/fullte…
1/10
Unexpected perk of my pediatrics rotation:
Never in my life have I been congratulated more often than when I'm lost in a hospital, asking for directions to the nursery 👶
Sébastien Maillé retweeted
🤓 Well, actually, David Marr famously said that the brain can be divided into three levels of squishyware:
1. The squishy thinky bit.
2. 70% water Rube Goldberg machine.
3. Warm jello nutrition facts.
Sébastien Maillé retweeted
Job alert! The Naud lab is looking for a postdoc in neuroAI to work on a project close to Neuromorphic computing. See the job post here: neurodynamic.uottawa.ca/oppo…
Sébastien Maillé retweeted
Some free serotonin for your browser!
Interested in our value prediction theory 👇, but not sure how it works? Try playing with the model parameters to see how they affect the activity patterns of serotonin neurons (blue) in an animal waiting for reward.
efharkin.com/blog/2023-10-va…
Sébastien Maillé retweeted
1/8 Check out our pre-print on @bioRxivpreprint! In this article, we discovered that distinct forms of synaptic plasticity of adult-born neurons in the OB are involved depending on the complexity of odor-learning paradigms and sensory inputs. More information and a link below.
ALT Distinct forms of structural plasticity of adult-born interneuron spines induced by different odor learning paradigms.
Interested in behavioral timescale synaptic plasticity (BTSP)? Associative learning? Eligibility traces? Temporal credit assignment problem?! Check out our preprint 👇! (1/13) #synapticplasticity #BTSP @NeuroNaud @JCBeique
biorxiv.org/content/10.1101/…
Sébastien Maillé retweeted
Truly thankful to have had the opportunity to present my PhD work conducted in @JCBeique’s lab at the Dendrites Gordon Conference last week! @GordonConf
Sébastien Maillé retweeted
What does the serotonin system compute? 🤔
🎉 I'm excited to finally be able to share a long-term project with @JCBeique and @NeuroNaud to create an experimentally-constrained bottom-up model of the dorsal raphe nucleus, just published in @eLife!🎊
doi.org/10.7554/eLife.72951
1/13
Sébastien Maillé retweeted
Can I share my long-winded justification for why I see bursts in my cereals? "Silences, spikes and bursts-three part knot of the neural code". With @mossy_fibers and @Z_Friedenberger.
arxiv.org/pdf/2302.07206.pdf
Sébastien Maillé retweeted
Landmark $5M gift from Camille Villeneuve promises to drive innovative results at the uOttawa Faculty of Medicine and Telfer School of Management.
uottawa.ca/about-us/news-all…
ALT From left to right: Dr. Jean-Claude Béïque, associate professor in the Brain and Mind Institute, Mr. Camille Villeneuve, Dr. Marc-André Langlois, professor in the Department of Biochemistry, Microbiology and Immunology and Executive Director of the Coronavirus Variant Rapid Response Network (CoVaRR-Net), Dr. Meghan McConnell, associate professor in the Department of Innovation in Medical Education, and Bernard Jasmin PhD, Dean and Professor, Faculty of Medicine.
Sébastien Maillé retweeted
A surprising attribute of dendrites is that they seem to control the dispersion of inter spike intervals. They also control gain and act as ANNs but somewhat less readily. Work from @Z_Friedenberger:
biorxiv.org/content/10.1101/…
#neuroscience
*Flying home from #SfN2022*
Customs agent: Welcome home, Mr Maillé
Me: Thanks, you too!
What a week. I think I’m due for some rest 😅
Sébastien Maillé retweeted
Judging by how my feet feel, I'm pretty sure I managed to pack three years of SFN into the past 5 days.
Sébastien Maillé retweeted
🚨 BIG DATA RELEASE 🚨 We are beyond excited to announce the release of our Brain Wide Map of neural activity during decision making! It consists of 547 Neuropixel recordings of 32784 neurons across 194 regions of the mouse brain 🐭🧠
(1/7)
Sébastien Maillé retweeted
What does serotonin do in the brain? If you're at #SfN2022, check out @JoanafaCatarino's poster where she will present our work on the effects of serotonin stimulation on neural dynamics across the mouse brain 🧠
📅 Tuesday afternoon, poster board TT7
Sébastien Maillé retweeted
This is such a shocking graph. 🇨🇦 is falling behind in science, already existing investments lose their value due to diminishing support for science, our best trainees won’t return after their postdocs. Canada urgently needs long-term vision and plan for science
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Sébastien Maillé retweeted
Looking forward to great discussions at #SfN2022
Presenting a poster on extended timescale plasticity & eligibility traces, Sunday Morning 8am-12pm 114.05 C38
Reply & DM me if you will be there!
#dendrites #synapticplasticity #neurosciences