Introducing AF-Pipeline, open-source Python package for extracting confident structures, interfaces from AlphaFold predictions isblab.github.io/af_pipeline… Github: github.com/isblab/af_pipelin…. Designed and developed by @Omkar_Golatkar_ , initialized by @KartikMajila , tested by @muskaanjl

In collaboration with Meera Sitaram's group we introduce a new discrete geometry-based method for integrative docking with chemical crosslinks (or other distance restraints). Work led by Yichi Zhang and @muskaanjl pubs.acs.org/doi/10.1021/acs…

New paper alert! Integrative structure of the desmosomal outer dense plaque from cryo-ET, X-ray, immuno-EM and biochemical data onlinelibrary.wiley.com/doi/…. Localizes IDRs such as Plakophilin-N. Beautiful work by former lab members @SatwikPasani @menonkavyaa

Some computational folks clustering together at #MBU50

[1/4] IMP developers/users, if you are bored of optimizing MCMC parameters (e.g., rigid body and bead move sizes) manually, we now have an algorithm and software to automate this. Introducing StoP (Stochastic Optimization of Parameters) by @SatwikPasani