Stem Cell & Aging Researcher at Geiger Lab, PhD. My tweets and opinions are my own.
Ulm, Deutschland
Joined November 2016
- Tweets56
- Following328
- Followers124
- Likes258
Our new study: Blood stem cells in distinct bone marrow niches vary in size and potential depending on the microenvironment. In aged niches, however, size no longer predicts function. doi.org/10.3389/fragi.2025.1…
New Research: Hematopoietic stem cell size heterogeneity is not linked to changes in stem cell potential of aged HSCs frontiersin.org/articles/10.… #FrontiersIn #Aging
Mehmet Sacma retweeted
Targeting CDC42 reduces skeletal degeneration after hematopoietic stem cell transplantation - Great work of Theresa Landspersky, Christina Schreck in collaboration with the geigerlab.com @stemcellniche @JanTuckermann in Ulm doi.org/10.1182/bloodadvance…
@BloodAdvances
Mehmet Sacma retweeted
Toller Erfolg für Jun.-Prof. Ani Grigoryan: Die Nachwuchs-Gruppenleiterin am Institut für Molekulare Medizin erhält einen @ERC_Research Starting Grant von 1,5 Mio. Euro für die Forschung an alternden Blutstammzellen🩸. Wir gratulieren! t1p.de/grigoryan *cl/📸privat
ALT Portraitphoto von Jun.-Prof. Ani Grigoryan, die gegen eine beige Wand lehnt. Sie hat schulterlange, dunkle, gelockte Haare und trägt ein leuchtend rotes, kurzärmeliges Top.
Mehmet Sacma retweeted
Great Start of the #GSCN23 Conference in Ulm with GSCN president Claudia Waskow and local organizer Hartmut Geiger. Let's start three days of discussion about stem cells! @berlinnovation @uni_ulm #stemcells #stammzellen – at Ulm, Germany
New study from geigerlab.com published in @emboreports on the role of pH in regulating blood stem cell potential via polyamines, potentially improving short-term culture protocols for transplantation and gene therapy: embopress.org/doi/full/10.15…
ALT https://www.embopress.org/doi/full/10.15252/embr.202255373
New study from geigerlab.com published in @emboreports on the role of pH in regulating blood stem cell potential via polyamines, potentially improving short-term culture protocols for transplantation and gene therapy: embopress.org/doi/full/10.15…
Mehmet Sacma retweeted
Join us! Few days left to register :)
Deadline extended to March 26! Register now for the FEBS Workshop on Aging in Hematopoiesis. Great Workshop esp. for junior scientists! For info:
aginginhematopoiesis2023.feb…
@FEBSnews @BritSocHaem @EHA_Hematology @BiochemSoc @ArchProjectMSCA
Join our Institute! PhD position in aging of human hematopoietic stem cells and aging of their environment:
stellenangebote.uni-ulm.de/j…
We want in situ 3d imaging to be possible for every lab. So, check out our detailed paper @STARProtocols about fast and high-res in situ 3D imaging protocol (iFAST3D) for stem cells and various niche components for many mouse organs. star-protocols.cell.com/prot…
Mehmet Sacma retweeted
Introducing the LSA Stem Cells Collection 2022:
Read original findings on progenitor cell regulation, intestinal stem cell clonal dynamics and breast cancer dormancy.
@ISSCR #ISSCR2022 #StemCell
life-science-alliance.org/co…
Our paper by Hageb et al. about accelerated clonal drift of aged intestinal stem cells is now published in @LSAjournal life-science-alliance.org/co… @uni_ulm
Mehmet Sacma retweeted
Neuer #SFB für die #uulm! — Die "Stellschrauben" des menschlichen Alterns im Fokus 👵👴
Der SFB 1506 „Alterung an Schnittstellen“ widmet sich einer der großen Herausforderungen der #Medizin: der #Alterung des #Menschen. t1p.de/q5ves *red/📸: AdobeStock @dfg_public
ALT Alte Menschen, Uni Ulm, #uulm, Alterung, Foto: ©Photographee.eu Adobe Stock
Mehmet Sacma retweeted
10.1182/blood.2021011775 I'm proud of my amazing team especially Theresa Landspersky and Christina Schreck and all collaborators for making this paper possible. This was a real team effort! Thank you! @stemcellniche @GoetzeKatharina and all those I ave no twitter-tag for
Our Nature News & Views @NatureNV piece "Exercise generates immune cells in bone" highlighting the latest work of Shen et al. (Sean Morrison lab) about a mechanosensing stem-cell niche promoting lymphocyte production:
The discovery that a type of bone progenitor triggers immune-cell production in response to movement could be harnessed for therapeutics, say H. Geiger & @stemcellniche go.nature.com/3uwh7wV
Mehmet Sacma retweeted
@BoShenUTSW discovered a periarteriolar niche for osteogenic and lymphoid progenitors in the bone marrow @nature. This niche requires mechanical stimulation! Exercise strengthens bone and immunity partly by forces transmitted into the BM along arterioles.
nature.com/articles/s41586-0…
Mehmet Sacma retweeted
Scientists from @uni_ulm show that aging of human #HematopoieticStemCells is linked to changes in Cdc42 activity.
Published in @Haematologica
bit.ly/3qrxnN0
Mehmet Sacma retweeted
Getting blood stem cells to leave their cosy home in the bone marrow is key for stem-cell transplants. A new study finds that spicy food can help do just that, say @DrStass & @iannisaifantis1 go.nature.com/34DDCol
Our paper about the Aging Niche nature.com/articles/s41556-0…
is part of Nature "Stem Cell Collection" nature.com/collections/ifacb… and Nature Immunology "Stromal–Immune Cell interactions" Collection nature.com/collections/ddbhb…
ALT The figures show blood stem cells (red) close to sinusoidal vessels (blue)