Immunologist, Translational Scientist. team member at $ZYME
Joined May 2009
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Nick Dawson retweeted
I often meet with grad students and postdocs interested in industry. I tell them how important it is to contact people. Most jobs aren't posted, and most people are nice. However, students often push back, thinking networking is transactional and a bit icky 1/
Nick Dawson retweeted
Biopharma co’s pitching VCs – when talking about the commercial opportunity for your drug candidates, it’s wise to exercise some rigor and conservatism. This will build credibility with investors as well as help you elucidate some of the key commercial questions early. To...1/11
Nick Dawson retweeted
Glycobiology feels very undervalued in its therapeutic potential. As we 1) learn more about the role of glycans in disease and 2) develop better tools to read and write glycans, I think we're going to see a big increase in the clinical impact of glycobiology: (1/7)
Nick Dawson retweeted
Wow! Isn't it incredible how #COVID19 vaccines keep people out of the ICU?💪🏻 #VaccinesSaveLives
P.P. asking some poignant questions. I hope they do go back to work and they find some answers. reddit.com/r/ontario/comment…
Nick Dawson retweeted
The @nytimes typically has excellent reporting, but this article on non invasive prenatal testing is quite misleading and unnecessarily alarmist. nytimes.com/2022/01/01/upsho…
Nick Dawson retweeted
private 🇩🇰 dermatology specialist Leo Pharma got their IL-13 approved in the US
LEO Pharma Announces FDA Approval of Adbry™ (tralokinumab) as the First and Only Treatment Specifically Targeting IL-13 for Adults With Moderate-to-Severe Atopic Dermatitis - businesswire.com/news/home/2…
Nick Dawson retweeted
New Research: Milk From Women Diagnosed With COVID-19 Does Not Contain SARS-CoV-2 RNA but Has Persistent Levels of SARS-CoV-2-Specific IgA Antibodies: Background
Limited data are available regarding the balance of risks and benefits from… frontiersin.org/articles/10.… #immunology
Nick Dawson retweeted
New Research: Tracing Human IgE B Cell Antigen Receptor-Bearing Cells With a Monoclonal Anti-Human IgE Antibody That Specifically Recognizes Non-Receptor-Bound IgE: Up to 30% of the population suffers from immunoglobulin E (IgE)-mediated… frontiersin.org/articles/10.… #immunology
Nick Dawson retweeted
Just published @NEJM
A striking 90% reduction in death for booster shots (vs not receiving the 3rd shot) among over 840,000 people, age 50 or older
nejm.org/doi/full/10.1056/NE…
Nick Dawson retweeted
New: Suppression of Human Dendritic Cells by Regulatory T Cells
bio-protocol.org/e4217
by Qing Huang, Avery J. Lam, @dom_boardman1, Nicholas A. J. Dawson, and @mklevings @UBC @BCCHresearch
#immunology #protocol @ScienceTM
Nick Dawson retweeted
NEW: people worry when they hear "40% of hospitalisations are fully vaxxed", but this chart shows that's actually good news.
The more people you vaccinate, the higher their share of hospitalisations, but the *total* number in hospital is a fraction of what it would otherwise be
Nick Dawson retweeted
Here’s the key table from @PHE_uk new report on vaccine efficacy against hospitalisation with Delta variant:
After 1 dose
• Pfizer: 94% effective
• AstraZeneca: 71% effective
After 2 doses
• Pfizer: 96%
• AstraZeneca: 92%
Full preprint here: khub.net/web/phe-national/pu…
Nick Dawson retweeted
9/If you are the National Advisory Committee on Immunization, then surely you can muster the resources to accompany your advice for “informed consent” with a tool that will enable that otherwise very complex informed consent process in the real world. It’s on you.
Nick Dawson retweeted
8/If you think your risk of contracting COVID is really low, here is a tool to help you to compare that risk with the risk of a vaccine complication: insert infographic decision aid comparing COVID vs VITT risk by: age, comorbidities, basic risk behaviours, community incidence.
Nick Dawson retweeted
7/There are always exceptions. If you live in a low risk neighbourhood, and/or are at extremely low risk (e.g. you never leave your house), it may be reasonable to wait for an mRNA vaccine, which doesn’t have this type of complication.
Nick Dawson retweeted
6/In fact, this complication is so rare that the average Canadian’s chances of dying in a car accident over 1 yr are about 10x higher than having this complication, and the average Canadian’s chances of dying of COVID since the start of the pandemic have been about 100x higher.