PhD Candidate studying #microglia and MND/ALS using #Zebrafish 🐟, #Microscopy lover 🔬, member of @mnd_mq and @ChungNeuro. 👨🏻🔬 He / Him
Sydney, New South Wales
Joined November 2017
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Check out our review in @FrontImmunol, where we take a look on what we know about the correlation between microglial function and shape (a.k.a microglial morphophysiology), covering different microglial morphologies and their reported function frontiersin.org/articles/10.…
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Andrés Vidal-Itriago retweeted
New Research: Microglia morphophysiological diversity and its implications for the CNS: Microglia are mononuclear phagocytes of mesodermal origin that migrate to the central nervous system (CNS) during the early stages of embryonic… frontiersin.org/articles/10.… #immunology
Is a ramified #microglia, a resting microglia? 🤔
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10%Yes
38%No
52%Depends
21 votes • Final resultsWe also discuss why the ramified/amoeboid paradigm is outdated, and why we should reconsider the “resting/activated” nomeclature when talking about different microglial morphologies.
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I want to thank everyone involved in this publication, including @NatalieMScherer @EmilyKDon @bertylee_ @ChungNeuro
Link to review: frontiersin.org/articles/10.…
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Andrés Vidal-Itriago retweeted
The post-translational modification SUMO affects TDP-43 phase separation, compartmentalization, and aggregation in a zebrafish model biorxiv.org/cgi/content/shor… #bioRxiv
Andrés Vidal-Itriago retweeted
We've developed smartphone fluorescence microscopes, aka Glowscopes. A few simple and inexpensive components convert your smartphone into a basic fluorescence microscope. 1/n
Andrés Vidal-Itriago retweeted
Check out our pre-print!
No more "activated microglia" please😆🤪.
I mean it.
And no more "M1/M2" nonsense either☠☠☠.
Defining Microglial States and Nomenclature: A Roadmap to 2030 @SSRN @cellpressnews Sneak Peek papers.ssrn.com/sol3/papers.…
Andrés Vidal-Itriago retweeted
The first 22 hours of #zebrafish development (blood vessels shown in green). Credit to @dancastranova and #WeinsteinLab @NICHD_NIH.
#ZebrafishZunday
Andrés Vidal-Itriago retweeted
Neutrophils (red) inside the hindbrain of a #zebrafish larvae infected with green fluorescent bacteria. Credit to Dr. Kar Yan Soh. #ZebrafishZunday
A good read for #microglia lovers 🤓
Authors propose the more precise term #microglial penta-partite #synapse, highlight the relationship between #microglia, #synapses, and the #cytokines that can be released by microglial cells in #health and #disease. Read more here: mdpi.com/1422-0067/22/24/131…
Andrés Vidal-Itriago retweeted
How a nerve ending looks. It has been broken open to reveal vesicles (orange and blue) containing chemicals used to pass messages in the nervous system:
#neuroscience [by Tina Carvalho]
Andrés Vidal-Itriago retweeted
Sometimes you don't even need a microscope to see cell phenotypes. Induced pluripotent heart cells can be seen beating in their wells.
(video by @JessicaGluckPhD)
Andrés Vidal-Itriago retweeted
New paper in @braincomms from @UniklinikBonn - discovery of a potential biomarker for #ALS academic.oup.com/braincomms/…
For those scientists who needed to hide who they were like Pio del Rio-Hortega, ‘father’ of Microglia. Happy #LGBTQSTEMDay ! – at Sydney, New South Wales
Andrés Vidal-Itriago retweeted
Congrats to all grant recipients! 🎉
@MND_RIA @mndaustralia continuing their legacy of getting innovative research projects off the ground!
We are eternally grateful for the "generosity of donors, and those who leave gifts in their will" as we work towards a world without #MND.
MND Research Australia has awarded over $3.1 million to support the best MND research commencing in 2022. MNDRA thanks our donors, those who leave gifts in their will, MNDandME, MonSTaR and the State MND Associations who fund this research.
mndaustralia.org.au/research…