Investor, econ wonk, Acct Prof., Lawyer, xCEO, Biotechs John 3:16 "Likes" not agree. LTBH & trading, Options. LQDA,OCUL,TGTX,HROW,ORCL,URGN,NFLX,CHTR

St Louis, MO
Joined March 2009
Elwood P. Dowd : Years ago my mother used to say to me, she'd say, "In this world, Elwood, you must be" - she always called me Elwood - "In this world, Elwood, you must be oh so smart or oh so pleasant." Well, for years I was smart. I recommend pleasant. You may quote me.
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The socialists and deep state have won. It’s a one way ratchet. Say what you want but is indisputable.. Check out this story: Guns or Butter? (found on beelineblogger.blogspot.com/…)
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$LQDA bingo, from the horse's mouth. The market does not yet get it. When it does, the stock will be over 70.
Replying to @deathtouch2k
Different situation with legal restrictions, but this is not being understood by the market about $lqda either. Credit to @Steven_Kiel
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zipjet retweeted
The videos emerging from Africa of Islamists slaughtering Christians are truly satanic. I have seen a video of Jihadists cutting the limbs off young Christian men and women before beheading them. I genuinely don't understand why nobody is talking about this.
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October 21 at 1:42 PM · MISSOURI HAS NO ILLEGALS; go figure... shouldn't the other states do the same? Missouri's approach to the problem of illegal immigration appears to be more advanced, sophisticated, strict, and effective than anything to date in Arizona. Does the White House appreciate what Missouri has done? So, why doesn't Missouri receive attention? Answer: There are no illegals in Missouri to demonstrate. (And the Media doesn't want to publicize that fact!) The "Show Me" state has again shown us how it should be done. There needs to be more publicity and exposure regarding what Missouri has done. Please pass this around. In 2007, Missouri placed on the ballot a proposed constitutional amendment designating English as the official language of Missouri. In November 2008, nearly 90% voted in favor! Thus, English became the official language for ALL governmental activity in Missouri. No individual has the right to demand government services in a language OTHER than English. In 2008, a measure was passed that required the Missouri Highway Patrol and other law enforcement officials to verify the immigration status of any person arrested, and inform federal authorities if the person is found to be in Missouri illegally. Missouri law enforcement officers receive specific training with respect to enforcement of federal immigration laws. In Missouri, illegal immigrants do NOT have access to taxpayer benefits such as food stamps or health care through Missouri Health NET. In 2009, a measure was passed that ensures Missouri's public institutions of higher education do NOT award financial aid to individuals who are illegally in the United States. In Missouri, all post-secondary institutions of higher education are required to annually certify to the Missouri Dept. of Higher Education that they have NOT knowingly awarded financial aid to students who are unlawfully present in the United States . It is important to remember, Missouri has been far more proactive in addressing this horrific problem. Missouri has made it clear that illegal immigrants are NOT WELCOME in the state and they will NOT receive public benefits at the expense of Missouri taxpayers. DON'T DELETE THIS, AMERICA. KEEP IT GOING UNTIL WE GET ALL 50 STATES TO COMPLY!
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The Machine That Replaces Pipes Without Digging
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She doxxed an ICE officer on Facebook and told people to "blast HER." Then investigators looked at her phone. Arely Guzman was a real estate agent in Albertville, Alabama, and one of the loudest anti-ICE voices in town. Her phone showed she was helping move illegal aliens, including Chinese nationals, and handling cash for a smuggling ring run by an inmate in an Oklahoma prison. She pleaded guilty in federal court this summer. This week a Texas jury convicted three more members of that same ring. Prosecutors say it made over $5 million. Their enforcer shot a man, tried to dissolve his body in acid, set it on fire, filmed it, and sent the video to the boss. That's the operation this "activist" was part of while she was out there trying to sic a mob on an ICE employee. Next time a Democrat tells you that unmasking ICE agents is about "accountability," remember her name. Sometimes the person screaming loudest about ICE has the most to hide. justice.gov/usao-wdtx/pr/hom…
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60 Minutes just got caught leaving out the best part. They sold America a sob story about a "Texas father" who got deported with no criminal record. What they didn't tell you is that he's an illegal alien from Mali who has had a final removal order from a judge since 2012. DHS's top lawyer pulled his file. The reason he gave for fearing a return to Mali was that he's gay. The man is married to a woman and has kids. That's the asylum scam in one case file. 60 Minutes didn't uncover a wrongful deportation. Either they got played, or they played you.
A Texas father who had lived in the U.S. for 25 years with no criminal record was finishing his night shift as an Uber driver when immigration agents detained him. Without being able to speak to his lawyer or a judge, he was put on a plane and sent first to Ghana, a country where he had no ties. He was then sent to his home country, despite a determination by a U.S. immigration court judge that he could not be deported there due to likely persecution. cbsn.ws/3Ude66r
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$TGTX Azer-cel, MS, RRMS, PPMS, and PIRA: PIRA is something that happens in both RRMS and PPMS. Saying that all 26 patients experienced PIRA in the last year does not tell us the patients are PPMS. They could be either. Both RRMS and PPMS patients exhibit PIRA. Remember that RRMS and PPMS represent 85% and 15% respectively of MS. I have been thinking of Azer-cel as a treatment for PPMS. IF it is really aiming at PIRA, then that has two important implications. First, the market is much bigger. Second, the approval hurdle will be higher. PIRA is really important. I do not think it is an over statement to say that once exacerbations are controlled by one of the treatments, that 100% of progression gets called PIRA. Again, PIRA is happening in lots of otherwise "controlled" RRMS cases.
$TGTX BRILEY PT $86 AZER CEL TGTX (Buy, $86 PT): Azer-cel’s first data show a clean safety profile, with efficacy now a function of dose &time. All 26 participants had progression independent of relapse activity (PIRA) in the prior 12 months despite anti-CD20 therapy. They had a median of 3 prior therapies, a median age of 51.5, a median of 8.6 years since diagnosis, and a median EDSS of 6.0, split across PPMS (9), naSPMS (10), and active SPMS (7). CRS (2/26, Grade 1-2) and ICANS (2/26, Grade 1) showed no dose trend from DL1 (30M cells) to DL6 (500M cells). There was no immune effector cell-associated hemophagocytic lymphohistiocytosis-like syndrome (IEC-HS), no graft-versus-host disease, no Grade 3 or higher infection, and 42.3% (11/26) of patients experienced Grade 3 or higher treatment-emergent AEs and 15.4% (4/26) experienced serious AEs (4/26).
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complete & total two-faced fraud
Robert Reich in 2025: Trump is a fascist dictator for even suggesting that a company be taken over by the government and for telling a CEO what to do. Robert Reich in 2026: SpaceX and Starlink must be taken over by the government. Small man, giant fraud.
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zipjet retweeted
Democrats Are Using the Soviet Playbook – Publicly Call for Nationalizing Private Businesses to Punish Elon Musk for Supporting Trump – Musk Responds with Fire thegatewaypundit.com/2026/10…
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Have policymakers in the EU, the UK and US states never heard of El Hierro? A small island with 11,000 residents and plenty of wind. An ideal testing ground for the promise of 100% renewable electricity, before making millions of people depend on it. They installed wind turbines with more than twice the island’s average electricity demand in capacity, plus pumped hydro storage. Yet in 2025, this system supplied just 44% of its electricity. Diesel supplied the rest. @mhtncontrarian explains why: during prolonged periods of low wind, the upper reservoir empties. Then the diesel generators have to take over. If this setup cannot deliver on its promise on a small, windy island, why are politicians so confident it will work on a vastly larger scale? They keep pushing ahead, with millions of people’s electricity supply at stake.
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zipjet retweeted
$TGTX BRILEY PT $86 AZER CEL TGTX (Buy, $86 PT): Azer-cel’s first data show a clean safety profile, with efficacy now a function of dose &time. All 26 participants had progression independent of relapse activity (PIRA) in the prior 12 months despite anti-CD20 therapy. They had a median of 3 prior therapies, a median age of 51.5, a median of 8.6 years since diagnosis, and a median EDSS of 6.0, split across PPMS (9), naSPMS (10), and active SPMS (7). CRS (2/26, Grade 1-2) and ICANS (2/26, Grade 1) showed no dose trend from DL1 (30M cells) to DL6 (500M cells). There was no immune effector cell-associated hemophagocytic lymphohistiocytosis-like syndrome (IEC-HS), no graft-versus-host disease, no Grade 3 or higher infection, and 42.3% (11/26) of patients experienced Grade 3 or higher treatment-emergent AEs and 15.4% (4/26) experienced serious AEs (4/26).
$TGTX AZER CEL data even more impressive when you look at baseline of these hard to treat patients - All 26 participants had PIRA in the prior 12 months; all had prior anti-CD20 therapy
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zipjet retweeted
WW II update: Nazis gain strongholds Britain…
🚨 NEW: Respect Orders are now live across England and Wales People who cause harassment, alarm or distress to others can receive bans from town centres, anger management courses or unlimited fines Anyone who breaches an Order can be arrested and jailed for up to 2 years
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There is something really concerning (and disappointing) going on in the US right now. A dangerous and preventable situation. Let me explain. nextstrain.org/avian-flu/h5n… 1/
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$TGTX You are years behind. In January 2024 I might have made that same statement. Years of reading patients comments, watching the KOL's in the field move failed patients to B, and the science on stronger binding and crap gap has conclusively debunked that view.
It's really unclear to me that ublituximab is at all differentiated from either ofatumumab or ocrelizumab and it seems like $TGTX is leaning heavily on "real-world" and post-hoc aka different flavors of bullshit data to push their drug. Obviously whatever they're doing they're having commercial success (a lot of aggressive marketing). On that note if you search "kesimpta" or "ocrelizumab" (but not "ocrevus" or "ofatumumab", go figure), a sponsored briumvi hit comes up first in the search results. That said I am long $TGTX (as well as $GMAB)
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🇨🇳🇺🇸 China pumped out MORE greenhouse gas last year than the U.S., India, Russia and Indonesia COMBINED. It’s responsible for 30.3% of all global emissions, around 16 billion tons, which is 2.7 times what America emits. The U.S. is a distant second at 11.4%, but its emissions are climbing faster: up 2.2% last year, while China’s barely moved at 0.1%. The world as a whole set a new record of about 55 billion tons in 2025. Maybe it’s time for Europe to realize its paper straws aren’t moving the needle 😆 Sources: ZeroHedge, European Commission (EDGAR), Visual Capitalist / Writer: Julie
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zipjet retweeted
Thomas Sowell grew up poor in Harlem and spent his twenties as a Marxist. A job inside the federal government ended that. Asked what changed his mind, he gave a one-word answer: "facts." Chicago sharpened the habit, with Milton Friedman teaching him, and he carried it through more than 45 books and a column in over 150 newspapers. From housing to the minimum wage, he checked what policies did and ignored what their authors promised. His most famous line sits in A Conflict of Visions: "There are no solutions. There are only trade-offs." Politicians hate that sentence because it puts everyone selling solutions out of work. Every program has a price, and voters rarely pay it. Sowell lived by it. When the Reagan administration put him on an economic advisory committee, he resigned after the first meeting. He pointed to Friedman's view that some individuals "contribute more by staying out of government." He retired from writing in December 2016 at 86 and turned 96 this June. His method fits on an index card: skip the promises, check the results. Now go ahead and do that with your local ruling class.
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