Principal Scientist, Regeneron
Joined May 2008
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Zak Singer retweeted
Thanks @newscientist @CarissaCWWong! great coverage
Viruses are already used to treat some cancers, and now it seems that combining them with another type of microbe - bacteria - makes the approach even more effective. newscientist.com/article/249…
Zak Singer retweeted
New publication out today in @natBME 🎉led by @zsinger JPabon demonstrating engineered bacteria launch and control a virus. A very cool cooperative microbial strategy for cancer therapy. Congrats to all! in collab with @RiceLaboratory
nature.com/articles/s41551-0…
Zak Singer retweeted
Wish you could control intercellular communication using protein circuits? First preprint from the lab! Proud of what @AlexVlahos, Jenny, and Carlos achieved, and how every lab member persisted through COVID. Also missing old colleagues @RonZhu2015, Lucy, and @ElowitzLab already.
Excited to share the first work from my post-doc with @SynBioGaoLab at @Stanford_ChEMH. This pre-print highlights a platform to control the secretion and display of proteins that is compatible with pre-existing protein based synthetic circuits.
Zak Singer retweeted
Excited to share our new preprint! We program probiotic bacteria to create a next generation anti-tumor vaccine that stimulates tumor neoantigen-specific immunity to control and eradicate solid tumors @ColumbiaCMBS @ColumbiaBME. biorxiv.org/content/10.1101/…
Zak Singer retweeted
New preprint!
Engineered bacteria launch and control an oncolytic virus biorxiv.org/content/10.1101/…
Exciting work from @zsinger jpabon & lab engineering bacteria to deliver viral RNAs that launch viral spread. We also engineer the virus to depend on bacteria. Congrats all!
Zak Singer retweeted
After a summer break, @wm_schneider and I are thrilled to invite you to the 3rd round of the Systems Virology Journal Club. We are hosting a stellar line-up of speakers working at the intersection of virology and systems biology.
Registration (free): forms.gle/edTyLwR8jWkhrRWw9 🧵
Zak Singer retweeted
Check out seqFISH in microbial populations!! a great collaboration with Dianne Newman's lab at Caltech! #seqfish #spatial #transcriptomics #microbial
In situ single-cell activities of microbial populations revealed by spatial transcriptomics biorxiv.org/cgi/content/shor… #bioRxiv
Excited to share our new work with the @RiceLaboratory and @tdanino on the single-cell analysis of viral replication and superinfection exclusion in alphaviruses! sciencedirect.com/science/ar…