Tweets are personal.

Joined April 2011
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I used to think this only happened in cartoons. 😂
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The Office of the Principal Scientific Adviser to the Government of India congratulates Dr. Ashoke Sen, @ictstifr-Infosys Madhava Chair Professor, Bengaluru, on receiving the Oskar Klein Medal for 2026. He is the first Indian physicist to receive this prestigious honour. Prof. Sen is globally recognised for his pioneering contributions to string theory, particularly his work on S-duality, the precision counting of black hole entropy and string field theory. His research has played a significant role in advancing modern string theory and deepening our understanding of fundamental physics. Jointly awarded by @Stockholm_Uni and the Nobel Committee for Physics of the Royal Swedish Academy of Sciences, the Oskar Klein Medal recognises distinguished contributions to physics. This recognition adds to Prof. Sen’s distinguished achievements, which include the Breakthrough Prize in Fundamental Physics (2012), the Dirac Medal (2014), the Padma Shri (2001) and the Padma Bhushan (2013).
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MAGA says Ilhan Omar isn't using her real name. Melania Trump was born Melanija Knavs. Ted Cruz was born Rafael Edward Cruz. JD Vance was born James Donald Bowman. Nikki Haley was born Nimarata Nikki Randhawa. Mike Johnson's real first name is James. Rand Paul is Randal Paul. Newt Gingrich was born Newton Leroy McPherson. But suddenly MAGA wants a congressional investigation into names?
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“The U.S. has benefited from the skills that Indians bring without having had to invest much in their education. Many have earned advanced degrees in America, but the bulk of their training happened in India. A more honest way to see it is that India, along with other poorer countries, has been subsidizing the United States.” theatlantic.com/ideas/2026/1…
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Imagine being the most unlikeable, unpleasant and creepy politician from a state that has jd vance and jim jordan!
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A powerful gene-editing technique has been used to edit DNA directly in a person’s body — the first known instance of such a treatment. go.nature.com/4Bgi3Yx
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Papers rejected by Nature: 1933 · Fermi’s theory of beta decay (“too remote from reality”) 1937 · Krebs’ citric acid cycle (Nobel Prize, 1953) 1973 · Lauterbur’s first MRI paper (Nobel Prize, 2003)
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Woooooowww. This is the confirmation we’ve been waiting for! Moderna and Merck’s personalized mRNA cancer vaccine reduced the risk of melanoma recurrence or death by 42% when added to Keytruda after surgery, compared with Keytruda alone! And yes, it uses the same mRNA technology behind the COVID vaccines!
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Good news: the extraordinarily unethical RFK Jr.-backed hepatitis B vaccine trial in Guinea-Bissau will not proceed. Withholding the birth dose from newborns would have put them at risk of preventable infection and lifelong consequences - including liver cancer.
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In den USA stehen wieder Wahlen vor der Tür...
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Nobel laureate @KarlDeisseroth came to neuroscience through words. His love of literature and writing drew him toward the human brain, and a required psychiatry rotation in medical school set him on the path to developing optogenetics. Here, he traces that journey.
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Imagine needing to do this as part of your weekly routine. I actually fell just watching it...
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🙄
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Why do South Asians get type 2 diabetes at much lower body weights? The answer is in their fat cells. These are fat cells from two young men with the same BMI. The South Asian man's are on the left. The white man's are on the right. At the same BMI as white Europeans, South Asians carry more body fat, bigger fat cells, more liver fat, and higher insulin. Here is what the studies show. 1. Same BMI, much bigger fat cells. In 29 South Asian and 18 white men, average age 27, BMI was 24 vs 23. Body fat was 22% vs 15%. The average belly fat cell was 3,491 vs 1,648 µm² in cross section. Treating the cells as spheres, that is about 3 times the volume of fat per cell on average. The samples in the image show an even larger difference. The larger the fat cells, the worse the insulin resistance. Visceral fat was the same in both groups. 2. Matched for age and BMI, still more insulin. Asian Indians matched to white adults had similar fasting glucose but higher fasting insulin, and they cleared glucose about 40% less well on a clamp test (4.7 vs 7.5 mg/kg/min). 3. Fat cell size explains much of the insulin gap. After adjusting for age, sex and BMI, South Asians had larger fat cells, liver fat of 9.9% vs 2.5%, and higher fasting insulin. Adjusting for fat cell size cut the insulin difference in half. 4. Lean and young. Among 482 lean young adults, insulin resistance was 2 to 3 times more common in Asian Indians than in any other group. The men had about twice the liver fat of white men. 5. It starts in childhood. South Asian children aged 8 to 11 in Britain were not heavier than white children, but their fasting insulin was 53% higher, with similar blood glucose. My view: fat cells can only store so much. When they are full, they become insulin resistant and release more fat into the blood, and that fat ends up in the liver and muscle. Insulin rises to compensate. South Asians appear to reach that limit at a lower body weight. For a South Asian person, a normal BMI does not mean normal metabolism. Fasting insulin, waist size and liver fat say more than weight.
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Countries with the most Indians: 🇮🇳 India: 1,450,900,000 🇺🇸 United States: 5,160,203 🇦🇪 UAE: 4,425,144 🇸🇦 Saudi Arabia: 2,594,947 🇲🇾 Malaysia: 2,019,600 🇲🇲 Myanmar: 2,009,207 🇬🇧 UK: 1,927,150 🇨🇦 Canada: 1,858,755 🇿🇦 South Africa: 1,697,506 🇰🇼 Kuwait: 1,152,175
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Can you see this? It’s my turn to be absolutely throttled by the algorithm.
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Ranked: The World’s Largest Economies in 2026 🌍  visualcapitalist.com/the-wor…
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Elizabeth Holmes once stood on a stage and said her company's blood test could see cancer coming 17 years before you ever got sick. She got that number from dead people. Back in 2014, at the Computer History Museum in Mountain View, she told the audience Theranos had worked with people at Johns Hopkins who showed you could see pancreatic cancer in blood "17 years before a tumor forms." There really was a Hopkins study with a number like that. It came out in Nature in 2010, and the way they got the number is pretty incredible. Christine Iacobuzio-Donahue and Bert Vogelstein took tumors from seven pancreatic cancer patients through a rapid autopsy program, which means the tissue was collected right after each person died. Then they read the mutations inside it. Here's why that works. Every time a cell divides, it picks up new mutations at a pretty steady rate. If you count the mutations, you can work backward and figure out how long the cancer has been growing, kind of like counting the rings on a tree. They found it took about 11.7 years to go from the first bad mutation to the first real cancer cell, then another 6.8 years before it turned into a tumor about the size of a plum. Add that up and you get around 18 years of cancer quietly growing in someone who feels totally fine. The researchers said this might someday give doctors enough time to catch it with a blood or stool test. That test didn't exist yet. Holmes took a maybe, based on tissue from people who had already passed, and told a room full of people her company had already done it in blood. When 60 Minutes called Johns Hopkins years later, Hopkins said it had never worked with Theranos. She also picked the one cancer where that kind of promise hits hardest. Pancreatic cancer still has a 13% five-year survival rate in 2026, the worst of any major cancer. If doctors find it while it's still in the pancreas, survival jumps to 44%. Only about 17% of people get diagnosed that early, because there's still no good way to screen for it. Hopkins actually shows up in the Theranos story twice. When Walgreens was deciding whether to put Theranos in its stores, it brought in a Hopkins team to check out the technology. One of the Hopkins scientists told Holmes they'd need one of her machines in their lab in Baltimore. She said sure. The machine never showed up. The review was done using data Theranos handed over, and according to Walgreens' lawsuit, it called the technology "novel and sound." Walgreens went ahead with the deal. That's how she got away with it for so long. Anyone could look up the Hopkins study, and her 17 years was close to the real math. The one thing nobody in that room could check was whether her machine could see any of it, and that was the part she invented. There's a scene in Nathan Fielder's new documentary where he asks her what her definition of a lie is. She'd already answered it on that stage back in 2014.
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Scientists train for years to do science but we get almost no training in how to talk about it. In a way it makes sense - science and communication are two totally different disciplines. But these past few years have shown us just how important it is to master these skills. This week on alpha, I’m talking with scientist-turned-science-communication expert @sarakyeo who has so much wisdom to share. If you are a scientist, I highly recommend you check this one out. And did you know a dad joke can make a scientist seem more trustworthy than a clever, sarcastic one? Good news for me :) Comic credit: @Argyle_Sweater
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