Exploring and Exploiting the Functional Capabilities of Nucleic Acids
Joined May 2014
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BurkeLab retweeted
BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
BurkeLab retweeted
If you’re into DNA, go to minute 13-14. This is so cool!
we made a DNA replica of a NERF blaster with @MarkRober! currently the #1 trending video on @YouTube with more than 3M views in less than 12h 🤯check it out! 🧬youtu.be/9c2NqlUWZfo?si=h0dB…
BurkeLab retweeted
#SAMURI is a new #ribozyme for RNA-catalyzed labeling of RNA. It uses a new cell-permeable SAM analogue and generates a novel propargylated nucleotide in RNA. Check out the full story doi.org/10.1038/s41557-023-0…
rclcu.be/dlcxN
New #ribozyme #SAMURI uses a new synthetic cofactor to make #RNA in living cells accessible for #ClickChemistry: Congrats on this publication @NatureChemistry to @HoebartnerLab @JoergLab @Helmholtz_HIRI! ➡️ go.uniwue.de/ribozyme-samuri
ALT SAMURI is a new ribozyme that attaches a targeted modification to cellular RNA for click chemistry. (Picture: Working group Claudia Höbartner / University of Würzburg)
BurkeLab retweeted
Happy pi approximation day!
Today's date, 22 July, can also be written as the fraction 22/7, which is equal to 3.14285714, an approximation of π, correct to two decimal places.
ALT A golden brown apple pie with the 'pi' symbol cut into it.
BurkeLab retweeted
A Biochemist and a Geologist walk into a bar and try to solve the origins of life problem.
Bartender to them: how on earth did life begin?
Them: Exactly!
BurkeLab retweeted
Very cool work. Reminds me of a paper from @ProfTomEllis lab that I believe was the first to use a fluorescent aptamer + protein (doi.org/10.1021/sb400089c) and inspired some of my own work with @BurkeLabRNA doi.org/10.1021/acssynbio.7b….
BurkeLab retweeted
Expanding the scope of RNA-catalyzed reactions @Uni_WUE. This work ow.ly/qXAX50OXTr3 #AngewandteVIPs shows how to install a formyl group in RNA using the methyltransferase ribozyme MTR1. exciting applications for site-specific fluorogenic labeling of RNA and more.
Ribozyme-Catalyzed Late-Stage Functionalization and Fluorogenic Labeling of RNA (Claudia Hoebartner and co-workers) @Uni_WUE @HoebartnerLab #AngewandteVIP #openaccess thanks to #projektDEAL ow.ly/qXAX50OXTr3
BurkeLab retweeted
Looking for curious postdocs, lab techs, and students who love tinkering with the building blocks of life and pondering deep questions about life's origin and evolution. Please spread the word. For more information, please visit dasguptalab.com (3/3)
BurkeLab retweeted
Love to see it @BurkeLabRNA!
@NADFDGD check out the acknowledgements (and data)!
BurkeLab retweeted
If you are a student and want to go to a conference on or after June 3rd, consider applying for the Soffen Fund! Applications due by 5 pm ET May 8, 2023. soffenfund.org/
BurkeLab retweeted
Happy #DNADay ! May all the structures you see today be right-handed 😁🎉🧬
BurkeLab retweeted
On DNA Day I want to recognize Gobind Khorana, who painstakingly constructed the first synthetic gene: E. coli tyrosine tRNA. Took only 7 years, and arguably also invented PCR along the way.
BurkeLab retweeted
You've probably heard about deep sea hydrothermal vents, but did you know they also exist in shallow waters where they can experience wet-dry cycles? Check out the review by @OHLlab Laurie Barge and @priceoceans to learn more! nature.com/articles/s41561-0…
BurkeLab retweeted
Look what we found in Ohio. Present in at least 20 sewershed samples over the last 6 months.
B.1.1 derivative (person infected for over 2 years).
About 94 genome changes (71 non-synonymous). Highly accumulated in Spike.
Many familiar cryptic mutations.
BurkeLab retweeted
Congrats to my longtime friend and former colleague @JordynLucas2 on defending her doctoral dissertation in Biochemistry from the @BurkeLabRNA at Mizzou this past week! 🥳
BurkeLab retweeted
A fantastic journey that started in June 2014 when I was a passionate PhD student, then a small break to return in April 2016, right after my PhD defense, to start my postdoc. Since then, I became a @Mizzou Faculty and I built a family with @AzCecchini. Lots of adventures!