@Cas_Fuchs

Assistant Professor @MaastrichtU / Expert Consultant Nutrition @VismaLeaseaBike / Human Physiology | Muscle Metabolism | Sports Nutrition | Recovery Strategies

 Maastricht
scholar.google.com/citations?user=zviXlCcAAAAJ&hl=en
Joined January 2015
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New Twitter account! My old account (@27CJ) got hacked a week ago (and twitter doesn't have the capacity to solve it 🤷‍♂️). If there is anything suspicious coming from that account, please spread the word it is not coming from me.
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Our new study: Do anabolic-androgenic steroids increase organ size in bodybuilders? ✅Full-body MRI ✅Muscle and organ volumes ✅Natural and enhanced bodybuilders Let’s break it down! 1/9 @Cas_Fuchs @MSSEonline
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Cas Fuchs retweeted
Dr. Myohead@DrMyoheadMay 15
When Size Goes Inside: Visceromegaly in Bodybuilders Is Not Attributed to High Protein Intake but More Likely Associated with the Use of Appearance- and Performance-Enhancing Drugs Great work from @Cas_Fuchs @JornTrommelen et al tinyurl.com/2kzpxb8e
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Therefore, D2O can be used to reliably assess human hepatic DNL in repeated measures designs with at least 3 weeks between measures Crossovers are powerful designs to efficiently detect small differences in hepatic DNL Thanks @TheBHF for funding doi.org/10.1152/ajpendo.0007…
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Is human energy expenditure constrained? See below for a thread based on a debate I participated in last year
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Big congratulations to Nutrition Tactics team member Milan Betz (@MilanWBetz) on successfully defending his PhD! See thread below for infographics on his PhD studies & link to the full thesis. 1/7
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New paper from @CNEM_Bath in @JPhysiol led by @lfbradshaw Isolating the effects of carbohydrate and lipid availability on exercise-induced skeletal muscle signalling doi.org/10.1113/JP289864 (1/7) #exercise #metabolism #muscle #fasting
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Muscle preservation during hospitalization: energy balance, protein intake, and habitual physical activity journals.lww.com/co-clinical…
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Breakfast consumption does not rapidly increase liver or muscle glycogen content in well-trained cyclists From @Cas_Fuchs et al. journals.physiology.org/doi/…

Breakfast consumption does not rapidly increase liver or muscle glycogen content in well-trained...

A carbohydrate-rich breakfast is commonly consumed by cyclists to compensate for an overnight decline in liver glycogen content and, as such, to maximize liver glycogen stores in the hours before...

journals.physiology.org
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🚴‍♂️ Breakfast may not “top up” liver glycogen as quickly as you might think. Excited to share our new study, now online (in press) in the American Journal of Physiology – Endocrinology and Metabolism: journals.physiology.org/doi/…
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Key findings: -Muscle glycogen concentrations and content did not change. -Liver glycogen concentration rose postprandially, but total content did not because liver volume declined at the same time.
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-These results highlight the importance of considering liver volume changes when interpreting glycogen storage responses. Still in press, with the final version on the way, but glad to already share these insights.
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Helpful review from @Cas_Fuchs Muscle preservation during hospitalization: energy balance, protein intake, and habitual physical activity journals.lww.com/co-clinical…

Muscle preservation during hospitalization:... : Current Opinion in Clinical Nutrition & Metabolic...

Purpose of reviewMuscle loss during hospitalization is a major clinical concern, as it has been associated with reduced physical function, quality of...

ovid.com
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NEW PAPER At recent conferences I still see people reporting "responders" & 'non-responders" often prematurely See our latest paper led by Lorenzo Lolli & Greg Atkinson on how to detect responders & non-responders (treatment response heterogeneity) doi.org/10.1123/ijsnem.2025-…
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New insights into glycogen recovery in endurance athletes 🧵 1️⃣ Our new study in The Journal of Physiology tested how muscle + liver glycogen recover after exhaustive cycling in well-trained cyclists.
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3️⃣ Findings (2/2): Sucrose (glucose+fructose) proved very effective for rapidly restoring liver glycogen 7T 13C-MRS validated vs biopsies, enabling accurate non-invasive tracking of glycogen
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4️⃣ 👉 Takeaway for cycling & endurance sport: the liver refuels fast, but the legs don’t — full muscle recovery takes much longer. Critical for stage races & heavy training blocks. Stay tuned — more work is coming soon in this space. 📄 Full article: physoc.onlinelibrary.wiley.c…

Carbohydrate intake of 10 g/kg body mass rapidly replenishes liver, but not muscle glycogen...

Abstract figure legend Exhaustive cycling exercise substantially reduces liver and muscle glycogen stores. During 12 h of post-exercise recovery without carbohydrate intake, glycogen stores remain...

physoc.onlinelibrary.wiley.com
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Illness or injury can affect any of us — and often results in hospitalization. Yet the impact of hospital stays on muscle health is often underestimated. ⬇️
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•Even light physical activity, such as walking or simple bed-to-chair transfers, can help preserve muscle mass by stimulating muscle protein synthesis. •For patients unable to move voluntarily, neuromuscular electrical stimulation (NMES) has shown to preserve muscle mass.
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•Prehabilitation, especially ahead of elective procedures, may improve physical reserve and support faster recovery. The bottom line: Preventing muscle loss in the hospital requires a multimodal approach — combining smart nutrition, physical activity, and, if needed, NMES.
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