We study DNA topology, action of topoisomerses and DNA break repair to understand genome organization, dynamics and stability @CNIO https://xitter.cf/t.co/dnM8T3kdNr
CNIO (Madrid, Spain)
Joined December 2019
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It's been a long journey ...
Huge congratulations to everybody involved @CNIOStopCancer @cabimer, specially the leaders of all this @JoseT86910859 @GMillanZambrano
And thanks to collaborators @AguileraLab RS Williams Lab and Mario García Domínguez
New paper out in @ScienceAdvances
TOP2B activity is locally inhibited during the estrogen response to favour the accumulation of DNA supercoiling and regulatory chromatin contacts that trigger transcriptional induction
science.org/doi/10.1126/scia…
- Topoisomerase-induced DNA breaks in cancer chemotherapy. Building on the traditional research line of the lab
nature.com/articles/nature08…
science.org/doi/10.1126/scie…
Funding: @CaixaResearch and @ContraCancerEs
2. DSB repair and genome instability mechanisms. Following on our recent REPAIRome study
science.org/doi/10.1126/scie…
Funding: @AgEInves
1. DNA topology and topoisomerase function in genome dynamics and carcinogenesis. In the line of this preprint (just accepted for publication)
biorxiv.org/content/10.1101/…
Funding: @CaixaResearch
📢Please spread the word📢
Several postdoc positions (wet and computational) open in the lab to work on different research lines (see thread)
We seek highly motivated candidates to join our team @CNIOStopCancer
cnio.es/en/research-innovati…
E-mail CV and brief motivation statement