We study DNA topology, action of topoisomerses and DNA break repair to understand genome organization, dynamics and stability @CNIO https://xitter.cf/t.co/dnM8T3kdNr
CNIO (Madrid, Spain)
Joined December 2019
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- Following386
- Followers855
- Likes391
Cortés Lab retweeted
Researches at #cniostopcancer create the ‘human repairome’, a catalogue of DNA ‘scars’ that will help define personalised cancer treatments.
Published in @ScienceMagazine
bit.ly/4fGk4CV
Cortés Lab retweeted
🧬The human repairome, REPAIRome, will allow researchers around the world to check out how each of the 20,000 human genes affects DNA repair.
Authors: @CortesLab @ErnestoLDA1811 Israel Salguero Daniel Giménez et al.
Funding: @CienciaGob @AgEInves @Europarl_ES
Cortés Lab retweeted
The repairome is ‘a platform for new discoveries', which has already helped to detect new genetic mechanisms involved in kidney cancer, and will allows progress ‘towards full control of CRISPR-Cas gene-editing technologies’.
Infographic: @CireniaSketches
bit.ly/4fGk4CV
Cortés Lab retweeted
Have a look at our review in @MolecularCell . We explore how histone modifications serve as integrators of genome activity, mediating communication between distinct DNA procesess. authors.elsevier.com/a/1kS2f…
Cortés Lab retweeted
En nuestro grupo en @cabimer investigamos sobre el síndrome por deficiencia en el gen CHD8. Buscamos a personas diagnosticadas con alteraciones en este gen, para asociarnos, intercambiar experiencias y aumentar el conocimiento sobre el síndrome.👇👇
Yeray ha sido diagnosticado de síndrome #CHD8, una enfermedad que solo sufren 167 personas en el mundo, 4 ellos en España.
“Quiero dar visibilidad a esta enfermedad para ayudar a mi hijo", explica su madre.
laopiniondezamora.es/castill…
Cortés Lab retweeted
Many thanks to @FundlaCaixa @CaixaResearch for the incredible support to work on this important problem together with Borja Ibarra @3M_lab and Cristina Ugalde
Postdoc positions will be opening soon!
Exciting times ahead!
🧬Errores en la replicación del ADN de las mitocondrias —un componente celular— se asocian a trastornos neurodegenerativos como el alzhéimer y el párkinson.
Con una ayuda #CaixaResearch, @rfleiro investigará cómo contribuyen estos errores a las patologías, lo que permitirá desarrollar nuevas aproximaciones terapéuticas.
tinyurl.com/5n7etfrr
Cortés Lab retweeted
Cuatro investigadores del #CNIOStopCancer reciben financiación @CaixaResearch.
cnio.es/noticias/cuatro-inve…
Cortés Lab retweeted
16/ 🏆Llegamos al ecuador de la ceremonia con los 6 reconocimientos en oncología, entregados por:
🔵 Juan Ramón Fuertes, director general adjunto @FundlaCaixa
🔵 Ignasi López, director del Área de Relaciones con Instituciones de Investigación y
Salud @FundlaCaixa
Cortés Lab retweeted
En este hilo de @caixaresearch puedes ver cómo fue la ceremonia y conocer a los demás investigadores e investigadoras homenajeados. Enhorabuena a todos.👏
xitter.cf/CaixaResearch/status/1…
1/ 📣 Hoy estamos en @CaixaForum Madrid para homenajear a los investigadores al frente de los 29 proyectos seleccionados en la convocatoria #CaixaResearch de Investigación en Salud 2024.
🔴Te contamos lo más destacado de la ceremonia:
Cortés Lab retweeted
An exciting meeting with lots of exciting results and interesting discussions. Thanks everyone for such a great time!
Cortés Lab retweeted
A new paper from @Lauberthlab by @BholaMannan and Kouki Abe shows how RNA and TOP1 work together to regulate DNA topological stress during transcription @MolecularCell. It was a pleasure working with the Mondragon, @EVNmoreRNA , @JohnFMarko , and He labs. authors.elsevier.com/a/1jd-m…
Cortés Lab retweeted
Having a hard time with #CRISPR HDR? Your cells might be fighting against you! TREX1 nuclease, high in some cells, eats up HDR donor templates. Check out our paper in @NatureBiotech for the story & ways to improve HDR. nature.com/articles/s41587-0… With @karasuerman1 & @J_Maciejowski
Cortés Lab retweeted
Wonderful resources.
UPDATED: we have identified 313 (!) funding opportunities and fellowships for postdoctoral fellows.
Download this database freely here: research.jhu.edu/rdt/funding…
For each entry, we provide description, amount, deadline, eligibility, and link to funder.
Good luck!
Cortés Lab retweeted
1/ 🤔 Do #chromatinlooping-mediated promoter-#enhancer interactions drive gene expression? Or is the local enrichment of transcription factors into hubs/#condensates the key factor? Our AC/DC model of gene regulation at bioRxiv doi.org/10.1101/2024.08.03.6… provides a new view on this.
Cortés Lab retweeted
📣New opportunity for #Postdoc researcher!📣
If you are interested in #telomeres and #genomestability, don’t miss this chance!
Application details at gimm.pt/jobs/junior-research…. Feel free to DM or email us ([email protected]) for more info.
Vacation code: IMM/CT/71-2024
Cortés Lab retweeted
📢 We are on the lookout 👀 for a PhD candidate! Fully funded 4-year project focused on the molecular dynamics of replication stress sensing at the replisome core. Please RT 🙏🏻 !
Cortés Lab retweeted
The mystery of how cells package their DNA and how it relates to cancer, the topic of CNIO’s & @CaixaResearch next international congress.
📅May 22nd-23rd: #CFM_Genome
👥Organized by: @KP_twitt_llo, @CortesLab, @ChromDyn y @nussenza. cnio.es/en/news/the-mystery-…
Cortés Lab retweeted
The first CNIO-Caixaresearch Frontier meeting in 2023🙌🏼❗️🚩May 22nd – 23rd
"Genome organisation and stability"
cnio.es/en/eventos/cnio-caix…
@KP_twitt_llo, @CortesLab, @ChromDyn, @nussenza
@CaixaResearch
Cortés Lab retweeted
🚨Job Opening: My lab is looking for an experimental PDRA with expertise in DNA nanotech and protein/DNA engineering to design new soft (topological) materials. The job is for 2 years and renewable until Dec2025. Deadline to apply 31 August. Please RT! 🧬🪢shorturl.at/ajSX6