@DDSoLab

We study the biology of normal B cells & their cancerous counterparts. Affiliated with @IcahnMountSinai @TischCancer @SinaiImmunol.

Joined June 2020
  • Tweets90
  • Following100
  • Followers153
11Media
The Dominguez-Sola Lab retweeted
St. Baldrick's Foundation@StBaldricksJun 7
Every child deserves the chance to survive and thrive. ✨ In honor of National Cancer Survivor Day, support lifesaving childhood cancer research if you believe in our mission: ow.ly/qiH450Z6lWQ Like & retweet to help us raise awareness. #cancersurvivor #togetherforthe5th
1
1
161
I think that the beauty (if I may) of this study is on the cell models that we built with @PapapetrouMDPhD. These are based on previous work in her lab exphem.org/article/S0301-472… and extremely valuable, it turns out, to understand how MYC works to transform cells.

Modeling myeloid malignancies with patient-derived iPSCs

The derivation of human induced pluripotent stem cells (iPSCs) in 2007 ushered in a new era in the modeling of human diseases, including those affecting the hematopoietic system [1–3]. Significant...

exphem.org
ISEH@ISEHSocietyApr 17
What happens when MYC signaling is sustained in hematopoietic cells? This study from @PapapetrouMDPhD and @DDSoLab examines how persistent MYC activity blocks differentiation and promotes leukemic transformation. Explore on exphem.org/article/S0301-472…
2
86
More posts to follow here and on Bluesky, where we just started an account in case you’re interested.
1
56
This is the latest work from the lab, in collaboration with Peter Heeger at @CedarsSinai. We had the precious help of many, including @FribourgLab, Alex Tsankov’s lab and @pardi_lab. You can find it at @JExpMed: rupress.org/jem/article-abst…

Complement-regulated homeostatic proliferation controls memory B cell longevity and repertoire...

Memory B cell longevity underlies protection against reinfection. In this study, Cody et al. show that complement activation regulates memory B cell longev

rupress.org
2
43
And we are back. Sorry for the radio silence to those that noticed
1
58
The Dominguez-Sola Lab retweeted
ISEH@ISEHSocietyApr 17
What happens when MYC signaling is sustained in hematopoietic cells? This study from @PapapetrouMDPhD and @DDSoLab examines how persistent MYC activity blocks differentiation and promotes leukemic transformation. Explore on exphem.org/article/S0301-472…
3
1
8
706
The Dominguez-Sola Lab retweeted
Keisuke_Ito_Lab@keisuke_ito_labMar 13
Replying to @Hema_News @IcahnMountSinai
Congrats to David (@DDSoLab), Eirini (@PapapetrouMDPhD), and the team on how persistent MYC rewires epigenetic landscapes and TF networks, revealing sustained deregulation drives MYC-driven leukemic transformation. @ISEHSociety
7
1
15
2,752
The Dominguez-Sola Lab retweeted
Fund NY Science
@FundNYScienceJan 9
Over 600 New Yorkers attended our Virtual Town Hall today to advocate for state-based science funding! We were joined by researchers, patients, institutions, and elected officials.
1
13
2
15
1,027
Support a New York State Biomedical Institute for a Healthier, More Affordable Future - Sign the Petition! c.org/YZj6QQZshL via @Change

Sign the Petition

Support a New York State Biomedical Institute for a Healthier, More Affordable Future

change.org
45
For those who were not aware of this initiative: c.org/jv6GfQwrjg

Sign the Petition

Support a New York State Biomedical Institute for a Healthier, More Affordable Future

change.org
40
We are extremely grateful to @StBaldrick especially to Jack's Pack @jackspack10 ,(stbaldricks.org/hero-funds/j…), for their support in our quest to find better treatments for Burkitt Lymphoma.

Jack's Pack- We Still Have His Back │ A St. Baldrick's Hero Fund

Did you know that 300,000 kids are diagnosed with cancer each year, worldwide? This St. Baldrick's Hero Fund is raising money for childhood cancer research to help these kids. Make a donation or get...

stbaldricks.org
St. Baldrick's Foundation@StBaldricks20 Nov 2025
Your donation dollars are turning hope into work that saves lives. 💚 Nearly $1.2 million in new grants just announced, and you can learn more about what you helped make possible: bit.ly/48b2cwJ
1
80
Dominguez-Sola @DDSoLab highlights work by Yada et al. (bit.ly/46Quz1c) which demonstrates that effective antibody affinity selection in germinal centers relies on the store-operated calcium entry component of the B cell receptor signaling network bit.ly/3Ndxmdd
2
4
2,164
177
The Dominguez-Sola Lab retweeted
Dr Alex Pike@Alexandra_Pike31 Oct 2022
A bunch of @StokesNeuro's trainees (from many points in time) put together a list of '10 simple rules for a supportive lab environment', inspired by the example he set. This has been a wonderful moment of reflection for me personally, as I start my own lab direct.mit.edu/jocn/article/…

10 Simple Rules for a Supportive Lab Environment

Abstract. The transition to principal investigator (PI), or lab leader, can be challenging, partially due to the need to fulfil new managerial and leadership responsibilities. One key aspect of this...

direct.mit.edu
8
155
34
563
The Dominguez-Sola Lab retweeted
Adrià Cañellas Socias@adriacanyellas9 Nov 2022
Incredibly excited to share our article “Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells” published today @Nature. I hope that you like it! A big thank you to all the co-authors for all their hard work! Highlights in the🧵 1/20 nature.com/articles/s41586-0…
28
162
26
708
The Dominguez-Sola Lab retweeted
Maly Cosco@malycat037 Oct 2022
Impactful words by @CarolynBertozzi today on how diversity in her trainees enabled creativity, not playing by the rules, and ultimately the work that built the field of bioorthogonal chemistry. Diverse science leads to better science!
49
1,753
553
5,953
To those that make good things happen. #SinaiNPAW2022 #PostdocAppreciationWeek
2
Definitely trippy science.org/doi/10.1126/scie…
The Dominguez-Sola Lab retweeted
Gitlin Lab MSK@GitlinLab_MSK20 Aug 2022
Recruiting for a fully funded post-doc position to join our growing team! Here’s a link to our lab website, dm or email if interested. Join an incredible, collegial environment @MSKcancercenter & SKI immunology in the heart of NYC. Pls RT! mskcc.org/research/ski/labs/…
Gitlin Lab MSK@GitlinLab_MSK7 Jun 2022
Interested in immunology/inflammation/genetics? The Gitlin Lab @MSKCancerCenter is looking to grow and recruit a post-doc! Great opportunity to dissect new pathways controlling the inflammatory response at both tissue & molecular levels. Email Adgitlin at Stanford dot edu
2
42
3
63
The Dominguez-Sola Lab retweeted
JRNLclub@JRNLclub21 Jul 2022
Gabriele Varano discusses the mechanisms underlying the selection of FOXO1 mutations in germinal-center-derived B-cell lymphomas. @ImmunityCP @DDSoLab @IcahnMountSinai @TischCancer @SinaiImmunol. #JRNLclub jrnlclub.org/research-films/…
5
11
Load more