Biologics Scientist at Gates Biomanufacturing Facitily @CUAnschutz. Former graduate student&postdoc @Musselmanlab
Denver, CO
Joined July 2018
- Tweets198
- Following100
- Followers79
- Likes844
Saumya De Silva retweeted
Happy to share our most recent work with @EmilyDykhuizen lab on the binding of PBRM1 bromodomains to RNA. As always a super fun collaboration! Led by @DsdSaumi and @DrDhimanA with contributions from @Surbhi__Sood @kilsiologia @morkos_henen @LabVogeli
academic.oup.com/nar/advance…
Saumya De Silva retweeted
Our work from the @Freudlab describing how the DNA repair protein APE1 binds and processes AP sites in the nucleosome is now out in @NatureComms!
@NIGMS @KUcancercenter
nature.com/articles/s41467-0…
Saumya De Silva retweeted
So excited for this collaboration with @chrmosimann laboratory! Thanks to FedEx for introducing us 😂 and to @NSF for supporting this project.
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Saumya De Silva retweeted
Great opportunity! 👇
We are looking for a synthetic chemistry/medicinal chemistry postdoc to develop inhibitors and probes of chromatin modifying proteins. See attached posting if you or someone you know is looking for a position. We need your help! tinyurl.com/f4umuut7 #chempostdoc
Saumya De Silva retweeted
Today, we announce the creation of the Gates Institute - a new institute to help scientists develop cell and gene therapeutics more effectively.
Learn more: bit.ly/3FBWTrF
Saumya De Silva retweeted
Please RT! Join us as a postdoc! Multiple funded positions available to study gene regulation in normal biology and disease. I am a passionate mentor, fostering innovative research and providing growth opportunities to meet your specific career goals.🧵
ajlab.org/postdoc-opportunit…
Saumya De Silva retweeted
Excited to finally share our new work from the
@Freudlab where we determine how the critical DNA repair protein APE1 recognizes and processes DNA damage in the nucleosome. Updated tweet 👇 (1/n)
biorxiv.org/content/10.1101/…
Saumya De Silva retweeted
Excited to have the lab’s first paper come out: authors.elsevier.com/a/1eZuN…
Saumya De Silva retweeted
ACS Chem. Biol. Visualizing Conformational Ensembles of the Nucleosome by NMR, Catherine A. Musselman* @MusselmanLab and Tatiana G. Kutateladze @CUAnschutz pubs.acs.org/doi/10.1021/acs… #NMRchat #NMR
Saumya De Silva retweeted
This was an awesome collaboration with @epicypher ! The dCypher approach allowed us to test how the nucleosome alters the pattern of histone PTMs selected for by reader domains. The nucleosome context is critical for understanding reader function! 👇 @CUAnschutz @IowaBiochem
We are thrilled to share our latest manuscript in collaboration with @MusselmanLab! We use the tandem chromatin reader protein BPTF to demonstrate the importance of the nucleosome context when defining histone PTM interactions.
(1/n)
biorxiv.org/content/10.1101/…
Saumya De Silva retweeted
Very excited to share the latest work by @DsdSaumi! Another super fun collaboration with @EmilyDykhuizen lab. @Surbhi__Sood @DrDhimanA @kilsiologia @LabVogeli @morkos_henen @CUAnschutz @IowaBiochem @Purdue_MCMP
biorxiv.org/content/10.1101/…
Saumya De Silva retweeted
Hey Twitter folks! I am thrilled to announce that I am recruiting participants for my project looking at graduate student women’s interests in chemistry faculty positions. We want folks from as many programs as we can get, so please share, and see the attached flyer for details!
Saumya De Silva retweeted
Me as a 1st year: Why do people hoard samples? Just toss them if you don't need them anymore.
Me as a 4th year: I keep this vial of mystery solution from my first year because I like the color.
Saumya De Silva retweeted
Masks r impt for unvaccinated ppl AND for those who've been vaccinated. We highlight a colleague & friend in the @ChromaTownie lab who is designing well-fitted masks w/an array of designs for sale! sciencein3.com/covid-19/the-…
Saumya De Silva retweeted
This was a super fun collaboration between our lab, @EAMorrisonLab, and @EvolBiochemist - led by undergrad @briannalup. We uncovered structural and functional coupling in the BRM AT-BD that is conserved over 1 billion years! @CUAnschutz @IowaBiochem doi.org/10.1016/j.jmb.2021.1…
Saumya De Silva retweeted
I have this conversation with my mom- literally every week. Every week. Why does she torture me so? 😂😭😳🤓 – at Davis, CA
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Saumya De Silva retweeted
Thanks @TrendsBiochem ! -- We had a lot of fun writing this review! @mkesghoneim @CUAnschutz
Now available online! A Review from Mohamed Ghoneim, Harrison Fuchs, and Catherine @MusselmanLab titled "Histone Tail Conformations: A Fuzzy Affair with DNA" - the discuss the dynamic nature of these interactions and how they influence chromatin states: bit.ly/3az0Q1a
Saumya De Silva retweeted
Papers are pouring out. My new paper in @NatureComms just came out today. How Zα could influence the #RNA binding specificity of ADAR1 #NMR #RNA @LabVogeli @CUAnschutz rdcu.be/ceL7f
