@EnginLaboratory

Associate Professor at the University of Wisconsin-Madison

 Wisconsin, USA
enginlab.org
Joined December 2017
  • Tweets686
  • Following183
  • Followers1.8K
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Feyza Engin retweeted
Kivanc Birsoy@KivancBirsoyOct 22
Our new work by @YuyangLiu1996! Short-lived proteins are key regulators of metabolic homeostasis. By investigating their degradation, we identified TXNDC15 as a regulator of ER protein degradation and lipid homeostasis via a catalysis-independent mech. cell.com/cell-chemical-biolo…

Genetic dissection of rapid proteolysis identifies TXNDC15 as a key factor of ERAD and lipid...

ER-associated protein degradation is central to organelle homeostasis, yet many regulatory components remain unknown. Liu et al. exploit the rapid turnover of short-lived proteins to identify TXNDC15...

cell.com
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Feyza Engin retweeted
Aydogan Lab@AydoganLabOct 9
It's so great to see efforts to begin unifying thoughts and findings on senescence, a field that has remained spread across multiple disciplines. Good job @NatureCellBio for taking the initiative, and @EnginLaboratory and colleagues for their efforts putting this together!
Feyza Engin@EnginLaboratoryOct 9
Thank you to Nature Cell Biology for inviting me to contribute to the Viewpoint “Goals and Challenges for Senescence Research”. It was a pleasure to discuss the challenges in senescence research and to exchange perspectives on where the field is heading. rdcu.be/1ELgsuzrWina
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Thank you to Nature Cell Biology for inviting me to contribute to the Viewpoint “Goals and Challenges for Senescence Research”. It was a pleasure to discuss the challenges in senescence research and to exchange perspectives on where the field is heading. rdcu.be/1ELgsuzrWina
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Engin Lab turns 12 today! A decade after we started, I’m proud of our contributions to science, grateful for the amazing trainees who have been part of this journey, and excited for what comes next. Here’s to the next chapter!
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This morning. Madison lake Monona ❤️
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Feyza Engin retweeted
Dr. Thomas Ichim
@exosomeSep 5
Tumors shut down immune response by producing high concentration of antioxidants Science paper science.org/eprint/YQNFAHKNF…

Tumor-derived antioxidants suppress immunity by depriving T cells of reactive oxygen species

Reactive oxygen species (ROS) promote genomic instability and fuel oncogenic signaling in cancer, but antioxidant therapies have so far failed to improve, or worsen, cancer outcomes. Emerging data...

science.org
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Feyza Engin retweeted
TV100
@tv100May 28
🐬İstanbul'un turkuaza bürünen sularında dolaşan yunus balıkları görüldü.
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The turquoise waters of Istanbul 😍
Hava Forum
@HavaForumMay 28
İstanbul'da turkuaz denizde yunuslar "günaydın" şovu yaptı.
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Feyza Engin retweeted
Hotamışlıgil Lab@gshlabApr 28
We are extremely proud and thrilled to announce our very own Dr. Hotamışlıgil @ghotamis has been elected to the National Academy of Sciences!! Congratulations on this outstanding achievement and recognition 👏👏👏😊nasonline.org/news/2026-nas-…

National Academy of Sciences Elects Members and International Members - NAS

WASHINGTON — The National Academy of Sciences announced today the election of 120 members and 25 international members in recognition of their distinguished and continuing achievements in original...

nasonline.org
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Here is the eprint of our recent review science.org/eprint/ZVKVHQ58B….

Beyond bystanders: How β cell stress shapes the autoimmune response in T1D

β cell stress not only drives loss of functional β cell mass but also may fuel autoimmunity in type 1 diabetes.

science.org
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Feyza Engin retweeted
Waggoner Lab@LabWaggonerMar 26
Review @ScienceTM @EnginLaboratory β cell stress not only drives loss of functional β cell mass but also may fuel autoimmunity in type 1 diabetes science.org/doi/10.1126/scit…
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I’m excited to share that our review article, co-authored with my colleague Dr. Decio Eizirik, is out today in Science Translational Medicine. science.org/doi/10.1126/scit…

Beyond bystanders: How β cell stress shapes the autoimmune response in T1D

β cell stress not only drives loss of functional β cell mass but also may fuel autoimmunity in type 1 diabetes.

science.org
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Feyza Engin retweeted
EuroFoot
@eurofootcom5 Dec 2025
🇳🇬💥 Victor Osimhen (26) with a FANTASTIC winning goal for Galatasaray. It was in the 92nd minute too! 🔴🟡
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Our new paper is out now in Nature Communications! We uncovered the function of XBP1 in beta cells of a preclinical model of T1D and identified unique and shared gene regulatory networks driven by IRE1 and XBP1. nature.com/articles/s41467-0…

Defining the role of β-cell IRE1α/XBP1 pathway and its gene regulatory network components in...

Nature Communications - Modulating the unfolded protein response (UPR) can induce protective dedifferentiation of β-cells in non-obese diabetic mice. Here, the authors show that β-cell...

nature.com
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We extend our sincere gratitude to our outstanding collaborator, Sushmita Roy, her team, the reviewers, and the editor. Congratulations to all authors!
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Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy | Nature nature.com/articles/s41586-0…

Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy

Nature - Acetyl-coenzyme A functions as a non-canonical signal to trigger mitophagy, and the acetyl-coenzyme A–NLRX1 axis underlies the KRAS-inhibitor-induced mitophagy response and promotes...

nature.com
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Hat-trick ⚽️⚽️ ⚽️ Three POTM awards in a row 🏆🏆🏆 Victor Osimhen 👏👏👏 #UCL
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Galatasaray beat the English champions. #UCL
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Feyza Engin retweeted
Guy Rutter1@guy_rutter30 Aug 2025
Our new report with #YaChiHuang ⁦#MarjanRupnik using high-speed imaging in pancreatic slices. Pancreatic α-cells are functionally heterogeneous and sex-dependently regulated by neighboring endocrine cells | bioRxiv biorxiv.org/content/10.1101/…

Pancreatic α-cells are functionally heterogeneous and sex-dependently regulated by neighboring...

Glucose and paracrine regulation on α-cells, particularly with respect to sex differences, remains unclear. Hence, we imaged islets of GluCre:GCaMP6ffl/fl mice in pancreatic slices, additionally...

biorxiv.org
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We are hiring! I am recruiting a postdoctoral fellow to join us studying cell stress responses and organelle communication in pancreatic beta cells. Cell and molecular biology background is highly desired. Interested? please contact me at [email protected]. hr.wisc.edu/postdoc-and-rese…

Postdoc, Postgrad, and Research Intern Vacancies

Browse Postoc and Research Intern vacancies at UW–Madison.

hr.wisc.edu
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