@ExtripWorkgroup

The EXTRIP mission is to provide evidence-based recommendations on the use of extracorporeal treatments for toxin removal in poisoning.

extrip-workgroup.org
Joined October 2014
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Replying to @ThommyTox @EMPoisonPharmD
I sound like a broken record. VD= 30L/kg. You're not removing any bupropion with MARS (or otherwise)
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EMCrit 370 - Extracorporeal Therapies for Poisoning #ExTRIP #NephMadness A panel of brilliant nephrologists discuss RRT for the Poisoned Patient. Modality choice, how to consult, access, hemodynamic stability and so much more! [#FOAMed] emcrit.org/370
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Replying to @baileympaterson
Happy to read the answers. Maximize clearance. You're not removing net fluid. HD is preferred.
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Stop the press! Our latest guideline: when to use dialysis for ethylene glycol poisoning. Perhaps our best paper yet. Hundreds of articles included, thousands of hours of work. ccforum.biomedcentral.com/ar…

Extracorporeal treatment for ethylene glycol poisoning: systematic review and recommendations from...

Critical Care - Ethylene glycol (EG) is metabolized into glycolate and oxalate and may cause metabolic acidemia, neurotoxicity, acute kidney injury (AKI), and death. Historically, treatment of EG...

link.springer.com
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3) Nothing corrects metformin-associated acidemia as quickly as HD
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2) The VD of metformin in AKI is actually quite low and you will remove it with HD.
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Replying to @MoreXGrok
As an author of the published paper referenced, here is my (MG) take: HD does it all. 1) It removes critical metformin from the blood (which is the toxic compartment, unlike lithium)
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Si eres un #believer de los #some en la formación continuada tienes que seguir a @ExtripWorkgroup: Perfil que se dedica a informar sobre las técnicas de depuración extracorpórea en casos de envenenamiento extrip-workgroup.org/ @SENefrologia @senjoven @SOMANEorg @nefrocat

extrip-workgroup.org

Blood Purification in Toxicology: ​Review and Recommendations

extrip-workgroup.org
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EXTRIP retweeted
AJKD@AJKDonline6 Jun 2022
Extracorporeal Treatment for Gabapentin and Pregabalin Poisoning: Systematic Review and Recommendations From the @ExtripWorkgroup buff.ly/31g3bxe (FREE temporarily)
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Checkout this handout from todays #AAEM22 talk on Toxic Ingestion and Dialysis. Thanks @ExtripWorkgroup for such great guidelines. dropbox.com/s/cskha940sk8bpo…
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Should we dialyze a patient who is toxic from high-dose or oral methotrexate? The jury is now out: cjasn.asnjournals.org/conten… Or on our website: extrip-workgroup.org/

Clinical Journal of the American Society of Nephrology

Explore Clinical Journal of the American Society of Nephrology, featuring peer‑reviewed articles, clinical studies, and the latest medical research.

journals.lww.com
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Replying to @drmjkulkarni
I would be extremely dubious about any potential benefit.
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EXTRIP retweeted
AJKD@AJKDonline6 Feb 2022
Extracorporeal Treatment for Gabapentin and Pregabalin Poisoning: Systematic Review and Recommendations From the @ExtripWorkgroup buff.ly/3AZi701 (FREE temporarily)
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EXTRIP retweeted
AJKD@AJKDonline3 Dec 2021
Extracorporeal Treatment for Gabapentin and Pregabalin Poisoning: Systematic Review and Recommendations From the @ExtripWorkgroup buff.ly/31g3bxe @sgosselinmd
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Replying to @MPCToxtidbits @EdinClinTox
All but 1 patient in the TK table for gabapentin had impaired kidney function. All had impaired kidney function for pregabalin. Half-life was during ECTR so includes ECTR and endogenous function, the latter being quite low presumably
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Just out: EXTRIP's recommendations for dialysis in gabapentin / pregabalin poisoning extrip-workgroup.org/gabapen…

GABAPENTIN / PREGABALIN | extrip-workgroup

extrip-workgroup.org
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not simu-live tweeting as absolutely cannot do justice to the excellent @ExtripWorkgroup session at #KidneyWk organized by @weddellite but want to highlight this @DavidJuurlink quotes the IBCC on the big screen! @PulmCrit Salicylate is a huge mimic!
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The Extrip guideline for baclofen is dedicated to @Nephro_Sparks
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ASN we are live
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All star extrip team out there. @DavidJuurlink @weddellite @MarcGhannoum @VijayanMD @nephrotox and Etienne Macedo
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