@GRabuffo

Institut De Neurosciences Des Systèmes - Postdoc

 Marseille, France
ins-amu.fr/
Joined November 2014
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New preprint: "A personalized map of where, when, and how to stimulate the brain to elicit controlled responses." biorxiv.org/content/10.64898… We use personalized AI surrogate brains to predict where, when & how to stimulate for reliable effects. Thread 👇 linkedin.com/posts/grabuffo_…

A personalized map of where, when, and how to stimulate the brain to elicit controlled responses

Brain stimulation has transformed the treatment of several neurological and psychiatric disorders and is now widely used to read out causal interactions in the human brain. However, its effects vary...

biorxiv.org
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Work done with @ireneaceropousa, Tomas Berjaga-Buisan, and @GustavoDeco at the Center for Brain and Cognition (CBC) @UPFBarcelona, as part of my Marie Skłodowska-Curie project CAERUS (grant agreement No. 101199894).
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New preprint out! How does criticality propagate from local neuronal circuits to whole-brain dynamics? We tackle this with a multiscale, connectome-based mouse model. 🧵/n 👉 biorxiv.org/content/10.64898…
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Also, check out our companion preprint where we test criticality empirically across local and global scales in simultaneous bilateral prefrontal cortex spiking recordings in freely behaving rats biorxiv.org/content/10.64898…

Intra-and Interhemispheric Signatures of Criticality at the Onset of Synchronization

The cerebral cortex must flexibly alternate between locally segregated activity that supports specialization and long-range interactions that enable integration. How cortical networks balance these...

biorxiv.org
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Big thanks to the solid team @ldallap1, @PierpaSorre, @FukaiTomoki, @MNPompili, Pietro Bozzo, Bach Nguyen, Damien Depannemaecker, Leonardo Gollo
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🧠⚡️Brain stimulation is powerful, yet its effects are notoriously variable: identical parameters can produce very different outcomes. In our new preprint, we show how the brain’s state before stimulation helps explain and reduce this variability. 1/n doi.org/10.1101/2025.09.18.6…
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Key message: variability is not just noise—it reflects structured brain dynamics that can be harnessed for more reliable, state-aware stimulation protocols. Preprint: doi.org/10.1101/2025.09.18.6… Code: github.com/grabuffo/State_De… 7/n
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With deep gratitude to my extraordinary co-authors @MariannaAngiol1, @FukaiTomoki, @GustavoDeco, @PierpaSorre , and @DaveMomi — this work would not have been possible without them. Supported by @MSCActions and @UPFBarcelona as the first step of the "CAERUS" project—more to come!
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