Assistant Professor | @AM_OMRF | Skeletal Muscle, Atrophy, Aging, Protein Quality Control (PQC) | Views my own | 📚💪🏼🇬🇧 #myotwitter
Oklahoma City, OK
Joined August 2011
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- Following303
- Followers10.8K
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Dave Hughes retweeted
As someone studying exercise-induced epigenetic memory, my first thought was: "we call this exercise". Mechanical loading deforms muscle fibres and nuclei. Do loading and unloading leave lasting mechano-epigenetic signatures that shape adaptive capacity with ageing?
Dave Hughes retweeted
The measurement, training and function of glycolysis is much less researched than mitochondrial biogenesis. Next week Kenneth M. Humphries will give the 26th HyperMet DFG Research Group talk on PFKFB2. Join here: teams.microsoft.com/meet/354…
Dave Hughes retweeted
Ets2 Is an Activity-Dependent Transcriptional Regulator of a Fast-Twitch Muscle Program
faseb.onlinelibrary.wiley.co…
Dave Hughes retweeted
Looking for a postdoc interested in ageing biology and proteostasis
📅 Deadline: Nov 15
More details in attached document
#Postdoc #PostdocOpportunity #Proteostasis #LongevityResearch #AcademicJobs #ResearchJobs
Dave Hughes retweeted
New @NatMetabolism paper: Systemic proteomic dynamics of acute exercise reveal genetic links to health and disease. tinyurl.com/bdh8rrbj
Dave Hughes retweeted
Congratulations to the CMR's @CaldowMarissa, @GordonSLynch and Team for their new paper, "Tomatidine Exposure During Early Myogenesis Promotes Hypertrophy of C2C12 Muscle Cells Through Increased Nuclei Accretion"
@CellAgAustralia #myotwitter
onlinelibrary.wiley.com/doi/…
Dave Hughes retweeted
Applications for our 2027 summer scholars are now open! ⭐🧬🔬
We’re looking for motivated, curious students to spend their summer at OMRF. During this 8-week, paid research experience, scholars work on individual projects in cutting-edge labs, guided by OMRF scientists.
Dave Hughes retweeted
An integrative multi-omic analysis of skeletal muscle in response to disuse and recovery resistance training in resistance trained and untrained young adults link.springer.com/article/10…
Dave Hughes retweeted
Spatial Transcriptomics Identifies Muscle Inflammation Susceptibility as a Distinct Periarticular Skeletal Muscle Phenotype in End-Stage Knee Osteoarthritis biorxiv.org/content/10.64898…
Dave Hughes retweeted
Our latest @MolMetab - a Clock/Ampk connection!
The Circadian Clock Component NPAS2 is modulated by AMPK and Regulates Substrate Utilization and Mitochondrial Function in Human Skeletal Muscle.
Great collaboration w/team @karolinskainst @Metabolcenter
sciencedirect.com/science/ar…
Dave Hughes retweeted
LATEST FREE PAPER : 60 g/h of CHO spares muscle but not liver glycogen using during HIT training. Congrats Sophie Hannon on latest PhD publication and all-co-authors on a great collaboration @Hearris
journals.physiology.org/doi/…
Dave Hughes retweeted
Thanks to this Legacy Grant from @OklahomaTSET, we will be able to continue helping patients and Oklahomans across the state!
Watch more from our groundbreaking in May: youtube.com/watch?v=NoKIThf5…
Dave Hughes retweeted
The hallmarks of skeletal muscle health
nature.com/articles/s42255-0…
Dave Hughes retweeted
Great to see the final version of this paper, thanks to @APSPhysiology and @APS_Function for highlighting our work!
Researchers find increased senescent #macrophage burden in muscle & #knee in preclinical #ACL injury model, and provide evidence that treatment with #senolytics is an effective strategy to mitigate posttraumatic #osteoarthritis severity. ow.ly/VpoN50ZzPlR
Dave Hughes retweeted
New #SkeletalMuscle paper: An integrative multi-omic analysis of skeletal muscle in response to disuse and recovery resistance training in resistance trained and untrained young adults. tinyurl.com/3pupd9n9
Dave Hughes retweeted
Fractionated proteomics identifies a protein network mitigating resistance exercise-induced damage in human skeletal muscle
nature.com/articles/s41467-0…
Dave Hughes retweeted
What happens when muscles stop feeling gravity? check out our new review paper in EMBO Rep: link.springer.com/article/10…. Congratulations to Sandhya and Samrat (@iamsamrat96). #MuscleBiology #Microgravity #SpaceBiology #Mechanobiology #MuscleAtrophy
Dave Hughes retweeted
Congratulations to the CMR's Dr Alastair Saunders @AlastairSaund from the @pgregorevic Lab for his new review, "Understanding cachexia and muscle dysfunction in the context of metastatic breast cancer"
@CancerCachexia #myotwitter
link.springer.com/article/10…
Dave Hughes retweeted
Congrats to Dr Chris Karagiannis @CKaragiann11012 of the @pgregorevic Lab for his first first-authored paper "Sex-divergent skeletal muscle remodeling emerges early in cancer cachexia" in @AJPCellPhys
#myotwitter
journals.physiology.org/doi/…
Dave Hughes retweeted
It is finally out!
JCI - Neuromuscular junction failure in sarcopenia is linked to NaV1.4 loss and reversed by ClC-1 inhibition jci.org/articles/view/190646