Med / Surg RN, Biologist, into microbial ecology & metagenomics, the relationship between DNA and its environment. Science, Health, Education & Journalism.

NNK / RVA
Joined November 2012
James Talarico tonight when comparing himself to Ken Paxton being bought by Elon Musk: "I want to be a candidate for Texas for everyone that can't afford one." Put that bitchin quote in bronze!
James Talarico in deep red Lubbock, Texas tonight
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Gameto my sixth unicorn was just sold to Ferring for $1.38bn here is the story. In 2020 I endowed a fellowship at Harvard in my father's name, Carlos M. Varsavsky, in the lab of George Church, one of the world's leading geneticists. Its goal: to make human eggs in the lab. Gameto grew out of it. My father was an astrophysicist and built the Instituto Argentino de Radioastronomía, Argentina's radio astronomy institute. He was a great teacher, at the university and at home. In a time without artificial intelligence, he was the artificial intelligence for me: he knew about everything. He died young. The fellowship carries his name. The fellowship paid for the PhD of Christian Kramme, a Californian geneticist who worked out how to make in the lab the cells that surround an egg in the ovary and help it mature. He is now Gameto's chief scientific officer. Ferring Pharmaceuticals, the Swiss fertility drug maker, is acquiring Gameto for up to $1.3825 billion. I am a co-founder, and this is the story of a company that set out to do one thing and was bought for another. I came to fertility in 2016 with Prelude Fertility, a network of US clinics I built, now part of Inception, the largest fertility network in North America. Inside those clinics I learned that IVF works, but it is brutal. For two weeks a woman injects herself with hormones so her ovaries release many eggs at once: around 28 shots, ultrasounds, blood tests, bloating and mood swings. Many women go through it once and never again. Every one who stops is a pregnancy that never happens. One question obsessed me: what if the treatment took three days instead of two weeks. I brought in Dina Radenkovic Turner as co-founder and CEO. She was 26, a physician trained at University College London and one of the brightest people I have ever worked with. Many questioned the bet on someone that young. Time proved us right. I had a moonshot and a fellowship. Dina turned them into a company. She looked at Christian's cells and saw a product: if the egg was out of reach, we would do the ovary's work in the lab. That became Fertilo. With Fertilo a woman takes hormones for two or three days, about 80% fewer shots. Her eggs are collected immature and spend a day in the lab with those cells, which do the ovary's job. Then they are fertilized as in any IVF cycle. The cells never enter her body. On December 16, 2024, the first baby conceived this way was born in Lima. By August there were five babies and more than twenty pregnancies. Three gentle cycles beat one brutal cycle nobody wants to repeat. With Dina at the helm, Gameto raised about $127 million in total from Overwater Ventures, Insight Partners, RA Capital, Two Sigma Ventures, BOLD Capital Partners, Future Ventures, Olivia Walton's Ingeborg Investments, Arcadia Investment Partners, PAGS Group, Pontiva Healthcare Partners and Portfolia, and from Anne Wojcicki of 23andMe, Bob Nelsen of ARCH Venture Partners, Stacey Bendet Eisner of Alice + Olivia and Chelsea Hirschhorn of Frida. Gameto is the sixth company I have built to pass a billion dollars, after Viatel, Yacom, Jazztel, Eolia Renovables, sold in 2017, and Inception/Prelude Fertility, Telecoms, internet, clean energy, clinics, biotech: nothing in common, and in every one the team mattered more than me.
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Inigo retweeted
This is kinda wonderful i love this
new load-bearing internet comment just dropped
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surely a sign that the SCC is listening to the governor and its employees
In the past 17 days alone, Dominion Energy has made $1,305,000 in political donations. Check it out here by scrolling down to Large Expenditure Reports: cfreports.elections.virginia…
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Yasmine Hamdan - Vows (2025)
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Going home to Albuquerque this August and seeing the Rio Grande near my parents’ house totally dry was devastating. This great reporting helped me understand why …
Believe it or not, I am aware of the fact that most people won't read a 16,000 word article about an actual blood-and-bullets war over water in the Rio Grande. So we made a 30-minute film. The filmmakers at TM Studios did an incredible job: youtube.com/watch?v=PBaMGnxt…
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Oh wow, that's evil as hell. Good business model, tho
JUST IN: California rehab operators accused of supplying illegal drugs to recovering addicts to keep them hooked & collect over $210 million from insurers.
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the way everyone just forgot that the president of the united states posted this
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YOU GOTTA VOTE VOTE VOTE
🇷🇸 The Student List has won the elections. Aleksandar Vucic has conceded defeat in Serbia’s elections. “It is clear that we lost these elections” Vucic announced.
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Three pro-Trump influencers on the same day in Belgrade. All have the same script: visit the St. Sava church in Belgrade and post on how Serbia is defending Christian values and criticize Vučić’s oponents one day ahead of national elections. Two are US-based but there are more.
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Elon wants chip fabs on the Moon now. Lunar soil is 20% silicon, he says, so you just mine it, refine it, stamp out solar cells and chips. Next level of the video game. His words. He's a walking 1954 Popular Science cover. "Moon Factories by 1975!" You can picture him red-faced at some poor SpaceX engineer, jabbing a finger at a render: "I saw this in a magazine! Why can't you guys do this?" Because the magazine was fiction, Elon. That's why. Boring question one: water. A single leading-edge fab burns through millions of gallons of ultrapure water every day, the kind filtered and polished until it turns chemically aggressive and rips ions out of anything it touches. Making it takes an industrial plant of its own. On the Moon you'd be chipping ice out of permanently shadowed craters at minus 230 C and feeding it through a purification chain that doesn't exist, powered by energy that also doesn't exist. Boring question two: shaking. Lithography machines sit on tuned vibration isolation, springs and masses and counterweights engineered around Earth's gravity down to the millimeter. Lunar gravity is one sixth of that. Every spring rate and tuned mass in the stack assumes 1 g, and the Moon has its own moonquakes nobody has fully mapped. So forget shipping a fab up there. You'd have to redesign the entire physics package from scratch, in a hailstorm of charged abrasive dust that eats seals and bearings for breakfast. And here's the part that makes it funny instead of just dumb. NASA studied all of this while Elon was still in college. Ignatiev and Freundlich published the actual paper in 1991: waste silicon from regolith processing, vacuum-deposited thin-film cells laid right on the surface. Serious work, fifteen years of it, and by 2005 the best anyone could promise was 5-8% efficient cells sprayed on melted moon glass, economical only at megawatt scale. Chips? Never in the plan. Not once, in thirty years of study. Then a 2006 follow-up walked back even the crude version, because melted regolith is too lumpy and dirty to make a decent substrate. The 2025 research gave up on purifying lunar silicon entirely and just ships the semiconductor layer from Earth. Thirty years of papers saying "hard pass" and this guy shows up with the crayon version of a 1991 NASA study, calls it visionary, and the fanboys clap like he invented the Moon. He isn't a genius ahead of his time. He's a man who skips the reading, and it shows every single time he opens his mouth just to pump his cult stocks.
Elon Musk explains how to build AI satellites on the moon from lunar silicon and aluminum, and says 500 to 1,000 terawatts a year cannot be launched from Earth “Well, the lunar soil is 20% silicon or something like that. So you can mine the silicon on the moon, refine it, and create the solar cells and the radiators on the moon. So get the radiators out of aluminum. So there’s plenty of silicon and aluminum on the moon to make the cells and the radiators. The chips you could send from Earth because they’re pretty light. But maybe at some point you make them on the moon, too." "Like I said, it does seem like a sort of a video game situation where it’s difficult but not impossible to get to the next level. I don’t see any way that you could do 500 to 1,000 terawatts per year launched from Earth.”
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Replying to @TheStalwart
A supreme court judge which was the personal lawyer of the president that just won, published a decision at 5:02pm (2 minutes after polls closed) that the voting period extended until 7pm. A lot of polls were already closed and could not be reopened. Only the ones that somehow knew about this extension beforehand could be kept open. I won’t type my conclusion here because I’m a Brazilian citizen and we do not have free speech laws like in the US. But you do the math
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I was eating 99 cent pizza as a broke ass intern in 2005 I cannot fathom the corners being cut to maintain a $1 price point in the year of our lord two thousand and twenty six
Beauty of NYC: The $1 slice, within two blocks of each other
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Replying to @thedimitri
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Inigo retweeted
I could stare at this for hours.
US County map based on how often each county is visited
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went to visit a friend who’s a ceramicist and works in a studio with no phone signal in a tiny yorkshire village. he doesn’t listen to podcasts or music, only occasionally uses the radio, and when I asked him what he thinks about all day he just said “well, pots mostly”
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Mike Davis, one of the greatest socialist writers in American history, died on this day four years ago.
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Inigo retweeted
The Bible Lesson Laura Theresa Alma-Tadema (British, 1852–1909) ca. 1883 Oil on canvas Allen Memorial Art Museum
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Sadly not on display, at least as far as I remember
Indian Summer Gari Melchers (American, 1860 - 1932) ca. 1901 Oil on canvas Virginia Museum of Fine Arts
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ETFs ☑️ The U.S. ETF industry experienced explosive growth in 2026; by early October, nearly 1,100 new ETFs had launched—a 43% increase year-over-year. ☑️ Meanwhile, leveraged ETFs reached a record 31.2% share of the market. This proportion has more than quadrupled since 2023, reflecting a sharp market shift toward products offering higher risk and amplified exposure. ☑️ Thematic ETFs also surged, with 48 launches in the third quarter and 46 in the second—more than double the previous quarterly records—offering investors targeted bets on trends like AI, rather than broad-based index exposure. Compared to investing in individual stocks, ETFs offer relatively greater stability.
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