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Infection & Immunity

@InfImmAg

Microbial pathogenicity, host defence, immunity to infection, vaccines and immune-therapy. BSI Infection and Immunity Affinity Group.

 United Kingdom
bsi.immunology.org/Infection-Immunity
Joined May 2015
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Important differences. AN EPIDEMIC is a disease that affects a large number of people within a community, population, or region. A PANDEMIC is an epidemic that’s spread over multiple countries or continents. ENDEMIC is something that belongs to a particular people or country.
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Prof. Akiko Iwasaki (@VirusesImmunity) profile picture
Prof. Akiko Iwasaki
@VirusesImmunity7 May 2022
In this study, @MiyuMoriyama et al investigate how well SARS-CoV-2 variants of concern (VOC) suppress MHC I needed for recognition by cytotoxic T cells. This question is important to understand how well the virus limits CD8 killing 🧵(1/) @biorxivpreprint biorxiv.org/content/10.1101/…
Image from Prof. Akiko Iwasaki (@VirusesImmunity)
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From ONS death certificates, 16,000 people have died so far in the Omicron wave. While this is far lower than the pre-vax Alpha wave in Jan 2021, it's almost the same as died during Delta wave - despite vaccination & in shorter time period. High nums of infections matter 6/14
Image from Prof. Christina Pagel - @chrischirp.bsky.social (@chrischirp)
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Nicolas (@Atipico1996) profile picture
Nicolas@Atipico199617 Apr 2022
Replying to @jneill
This is how Boris Johnson’s government wants to “live with Covid”, leaving thousands of emergency patients waiting for hours. This is criminal, but the public seems fine with it or maybe they don’t understand the issue.
Image from Nicolas (@Atipico1996)
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WHO African Region (@WHOAFRO) profile picture
WHO African Region
@WHOAFRO17 Apr 2022
Vaccines are safe and effective. ✅
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99% of the world now lives in polio-free countries. The finish line for #polio eradication is in sight Join the Global Polio Eradication Initiative to learn about the support needed to deliver on our promise to #EndPolio by 2026 Register now: bit.ly/3Ka8Fea 🗓️26 April
Image from WHO Regional Office for the Eastern Mediterranean (@WHOEMRO)
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📅 Tuesday 5 April 18:30-19:30 Join our next event with Prof Sharon Peacock and Dr @KaterinaGalai, who will talk about the impact of genome sequencing on the #COVID19 pandemic response in the UK and beyond. #CamFest @CamInfectDis Register now👇 cogconsortium.uk/cam-fest-co…
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A #booster #COVIDvaccine is the best protection against severe #COVID19 🦠💉 With the spring booster programme underway, it’s a good time to explore why booster doses are safe & effective at enhancing the immune response 💪 Download this infographic 👉bit.ly/3oGR7gX
Image from British Society for Immunology (@britsocimm)
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We're joining forces with @TheCrick & @NatImmunol to celebrate the #DayOfImmunology with a free hybrid event 🥳 An expert panel will explore why the #immunesystem attacks the body’s own cells & tissues in #autoimmune diseases on 28 April 💭 🗓 Register: bit.ly/350m7Su
Image from British Society for Immunology (@britsocimm)
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Andrew E Williams (@AndrewEWilliams) profile picture
Andrew E Williams@AndrewEWilliams19 Mar 2022
Highly informative thread. #COVID19 @InfImmAg
Prof. Christina Pagel - @chrischirp.bsky.social (@chrischirp) profile pictureProf. Christina Pagel - @chrischirp.bsky.social@chrischirp19 Mar 2022
THREAD: State of the pandemic in the UK (esp England) Hospital admissions are best way to compare waves right back to start - we are on wave 7 now! 4 of which happened since last July. So cases & admissions are rising - why? does it matter? where are we 2 years in? 1/13
Image from Prof. Christina Pagel - @chrischirp.bsky.social (@chrischirp)
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La Jolla Institute (@ljiresearch) profile picture
La Jolla Institute@ljiresearch10 Feb 2022
New work from LJI researchers makes it possible to tell the difference between T cell responses to #SARSCoV2 infection and T cell responses to a #COVID19 vaccine doi.org/10.1016/j.chom.2022.… @cellhostmicrobe
Graphical abstract showing a T cell-based assay allows discrimination of SARS-CoV-2 infection and vaccination

ALT Graphical abstract showing a T cell-based assay allows discrimination of SARS-CoV-2 infection and vaccination

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Immunologists agree 100%. Vaccines work and vaccines are everyone's best chance of not becoming I'll from #Covid19 and vaccines also reduce the chance of someone else being infected. Please get vaccinated (1 + 2 + booster). #VaccinesWork #BoosterJab #GetBoosted
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“a virus does not become endemic just because a government wants it to happen, and certainly not at a point when infections are running at their highest ever level.” Sky News
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🆕💥💥💥The first and the best peer review article to date from SA scientists that describes the genomic molecular profile, mutations and early transmission dynamics of ⭕micron, highlighting Transmissibility, immune evasion and infectiousness #IDTwitter nature.com/articles/d41586-0…
Image from Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward)
Image from Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward)
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Dr Andrew Furber (@FurberA) profile picture
Dr Andrew Furber@FurberA7 Jan 2022
Coronavirus: excellent public engagement resources from @britsocimm including on vaccines immunology.org/coronavirus/c… #Covid19UK
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John Burn-Murdoch (@jburnmurdoch) profile picture
John Burn-Murdoch
@jburnmurdoch25 Nov 2021
Nonetheless numbers are really rising. Tuesday 868, Weds 1,275, and since I posted the first tweet Thursday’s figure has come out: 2,465. Which means the wave chart now looks like this:
Image from John Burn-Murdoch (@jburnmurdoch)
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Adam Kucharski (@adamjkucharski) profile picture
Adam Kucharski
@adamjkucharski25 Nov 2021
Potential implications for antibody responses: 5/ teapawt.org/jbloom_lab/status/1464…
Bloom Lab (@jbloom_lab) profile pictureBloom Lab
@jbloom_lab25 Nov 2021
Here's how mutations in #SARSCoV2 Nu variant (B.1.1.529) will affect polyclonal and monoclonal antibodies targeting RBD. These assessments based on deep-mutational scanning experiments; underlying data can be explored interactively at jbloomlab.github.io/SARS2_RB… (1/n)
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Infection & Immunity retweeted
Adam Kucharski (@adamjkucharski) profile picture
Adam Kucharski
@adamjkucharski25 Nov 2021
Breakdown of mutation profile: 4/ teapawt.org/jcbarret/status/146397…
Jeffrey Barrett (@jcbarret) profile pictureJeffrey Barrett@jcbarret25 Nov 2021
Took a look at the spike mutations in B.1.1.529 this evening, and colour coded them (details below)...there is...not much green.🧵
Image from Jeffrey Barrett (@jcbarret)
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The brand new UK #COVIDVaccine #Research Hub celebrates the huge contribution of UK scientists to our understanding of how #vaccines can best protect us from #COVID19 🦠💉🔬 Funded by @UKRI_News Find out more here 👉covidvaccineresearch.org/
Image from British Society for Immunology (@britsocimm)
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🆕 Now online in our new edition of #Immunology News – we get the inside scoop from BSI member Dr John Tregoning @DrTregoning about his new book Infectious! Find out how the book pays homage to the #scientific innovations of the past century 👉 bit.ly/3DLY3z0
Image from British Society for Immunology (@britsocimm)
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