@JeremyJBerg

Assistant Prof of Human Genetics @UChicago. Working at the intersection of population, statistical and quantitative genetics. tweets my own. he/him/his

Joined November 2012
  • Tweets2.7K
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We are hosting the 2026 edition of the Midwest Population Genetics Meeting at UChicago on August 21 and 22! This is a trainee focused meeting with many opportunities to present!
Jeremy J. Berg@JeremyJBergMay 28
The abstract deadline for Midwest Popgen 2026 has been extended to June 12! jkreinz.github.io/mwpg2026/
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The abstract deadline for Midwest Popgen 2026 has been extended to June 12! jkreinz.github.io/mwpg2026/
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I am looking for a postdoc to work in theoretical population genetics. We focus on theory and methods for inferring demographic histories and selection using modern and ancient genomic data. Come join our amazing community in Chicago. More info here: steinrueckenlab.uchicago.edu…
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Extinction vortices are driven more by a shortage of beneficial mutations than by deleterious mutation accumulation biorxiv.org/cgi/content/shor… #biorxiv_evobio
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Yuval Simons@yuvalsim7 Sep 2023
I'm thrilled to announce that I've joined the Section of Genetic Medicine at the University of Chicago as an assistant professor! The Simons lab is officially open! yuvalsimons.org/

Yuval B Simons | Population genetics of complex traits

The Simons lab at the University of Chicago studies population, statistical and quantitative genetics. Understanding complex traits in the light of evolution.

yuvalsimons.org
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Michael Baym@baym14 Aug 2023
This isn't a new thought, but I'm wondering today how much of the pervasive sense of burnout or disengagement among life science professors today is a sense of soft institutional betrayal for the last three years. That our institutions do not share our morals
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Marida Ianni-Ravn@mkiravn30 Mar 2023
Super excited my new preprint with @FerRacimo and @fleventy5!! This is also *my first* preprint so I’m extra stoked. Here’s a thread about it… (1/?)
bioRxiv@biorxivpreprint29 Mar 2023
Exploring the effects of ecological parameters on the spatial structure of genetic tree sequences biorxiv.org/cgi/content/shor… #bioRxiv
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Jennifer Blanc@jblanc1213 Mar 2023
Our approach is simple to implement and can provide better protection against confounding than the standard PCA approach when the test of interest is known ahead of time
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Jennifer Blanc@jblanc1213 Mar 2023
We then show how to correct for this bias when testing for the association between PGSs and an ancestry gradient of interest in the prediction panel by leveraging the overlap in structure between the two panels
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Jennifer Blanc@jblanc1213 Mar 2023
Motivated by recent evidence of residual confounding in PGS, we first use a simple model of genetic relatedness to show how confounding in the GWAS biases the distribution of PGS in the prediction panel in a way that depended on the overlap in population structure between panels
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Jennifer Blanc@jblanc1213 Mar 2023
Super excited to share a preprint of work from my PhD with @JeremyJBerg 🎉 biorxiv.org/content/10.1101/…

Testing for differences in polygenic scores in the presence of confounding

Polygenic scores have become an important tool in human genetics, enabling the prediction of individual phenotypes from their genotypes. Understanding how the pattern of differences in polygenic...

biorxiv.org
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Sivan Yair@sivan_yair1 Mar 2023
If anyone knows of any data science / pop gen positions in industry please get in touch! NYC area or remote. @Color laid off ~50% of the company. Genomics R&D work basically out. Frustrating news, but proud of my contributions and grateful for all I learned & great colleagues.
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bioRxiv@biorxivpreprint27 Feb 2023
Interpreting population and family-based genome-wide association studies in the presence of confounding biorxiv.org/cgi/content/shor… #bioRxiv
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Thrilled to share that our manuscript on T2D genetic clustering is now published! Soft clustering analysis of type 2 diabetes loci identifies ten physiologically interpretable genetic clusters associated with distinct tissues and clinical outcomes. link.springer.com/article/10…

High-throughput genetic clustering of type 2 diabetes loci reveals heterogeneous mechanistic...

Diabetologia - Type 2 diabetes is highly polygenic and influenced by multiple biological pathways. Rapid expansion in the number of type 2 diabetes loci can be leveraged to identify such pathways....

link.springer.com
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David Tang@dtang200030 Nov 2022
super excited to share our new paper on polygenic epistasis! we introduce a new model and show how structured statistical epistasis can help us study complex trait biology. huge thanks to my friend and lab-mate @studyjeromics, and my mentor @andywdahl! biorxiv.org/content/10.1101/…

Factorizing polygenic epistasis improves prediction and uncovers biological pathways in complex...

Epistasis is central in many domains of biology, but it has not yet proven useful for complex traits. This is partly because complex trait epistasis involves polygenic interactions that are poorly...

biorxiv.org
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Doc Edge@DocEdge852 Nov 2022
At the same time, I saw more clumsy talk about human genetic and phenotypic diversity than I usually see at ASHG. Clumsy ~= categorical, simplistic, mixing environment and genetics without clarity, omitting of crucial caveats, and using outdated or loaded language.
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Doc Edge@DocEdge852 Nov 2022
A big theme of the meeting was taking human genetic research worldwide. That’s undoubtedly a good thing.
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Doc Edge@DocEdge852 Nov 2022
It was great to see so many friends at #ASHG22. There was also plenty of exciting research. At the same time, I left the conference with some concerns (thread)
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I'm recruiting PhD students and postdocs to join my group @MPI_EVA_Leipzig in 2023! If you are interested in primate functional genomics, cell culture systems, and/or complex skeletal traits, please apply!
MPI-EVA Leipzig@MPI_EVA_Leipzig14 Oct 2022
📢📢 Join our vibrant research community @MPI_EVA_Leipzig! We're offering PhD and/or postdoc positions in areas incl. primate behavior & evolution; human adaptation, ecology & culture; human evolutionary genomics. Check it out & apply by 1st December 2022! eva.mpg.de/career/positions-…

Positions available - Max Planck Institute for Evolutionary Anthropology

eva.mpg.de
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