Incoming PI at A*STAR GIS | Helen Hay Whitney Fellow | Ph.D @ChemistryMIT | Spatial omics 🔬and RNA biology 🧬 | Contacting my lab: [email protected]

Cambridge, MA
Joined March 2013
It's official! I will be joining @astar_gis as new PI this year. Looking forward to embarking my independent journey in Singapore! My lab will be at the intersection of genomics and RNA technology. We will be hiring at all levels. Email if you are interested! Check below⬇️ #newPI
11
19
2
237
22,446
I also want to thank many fantastic collaborators, mentors, mentees, and friends along the way. Truly too many to name!
4
901
I want to thank my incredible PhD advisor @WangXiaoLab for the unwavering support throughout the years! It's been a true honor working alongside so many brilliant scientists at Wang Lab @broadinstitute and Zhang Lab @BostonChildrens.
3
940
Excited to share our new protocol article! We present step-by-step workflows for STARmap PLUS, RIBOmap and TEMPOmap.
New Article! Spatially resolved in situ profiling of mRNA life cycle at transcriptome scale in intact cells and tissues using STARmap PLUS, RIBOmap and TEMPOmap bit.ly/4pLulCn
3
11
3,400
GENOME: THE GIS SPEAKER SERIES🧬 Join us at our next seminar by Dr. Rena Ren, Helen Hay Whitney Postdoctoral Fellow from Harvard Medical School/Broad Institute, hosted by Dr @ywan_wan Date: Mon 22 Sep 2025 Time:  10AM (SGT, GMT +8) Venue: Online via Zoom Link: zoom.us/j/96268397141?pwd=uY… Webinar ID: 962 6839 7141 Passcode: 085920 More details: a-star.edu.sg/gis/news-event… #GISSPEAKERSERIES
2
8
1,529
Congrats Yuting!
Our research is online! We show that while young HSCs are fairly uniform, old HSCs harbor both “old” and “younger” subsets. Reducing the “old” subset alleviates aging phenotypes in old mice! doi.org/10.1038/s41422-024-0…
2
1,004
The new Dr. Hailing Shi’s lab at @EmoryUniversity is hiring at all levels! @HailingShi is so knowledge and such a wonderful person to work with! Please check out the lab description here. #newPI
1
6
25
2,361
Check it out: a paper outlining a new computational method (known as CAST) from the @WangXiaoLab was recently published in @naturemethods! chemistry.mit.edu/chemistry-…
2
3
11
4,052
Spatial omics technology is transforming our understanding of in situ RNA biology. We are grateful for the opportunity to publish this review in @MolecularCell. We hope this will be a useful resource for the community. @HailingShi @nemo08061 @WangXiaoLab
Online Now: Spatial omics advances for in situ RNA biology dlvr.it/TD8Y9t
12
1
53
8,879
Another new work from Xin! STARmap and RIBOmap in thick tissues (200 μm!!)
1
3
1,106
New method that detects single-nucleotide variation by in situ sequencing! Congrats Xin🎉
Excited to share SWITCH-seq, a multiplexed in situ RNA sequencing method that discerns single-base variations in rRNA. Very honored to work with @D_Rothschild_ , and Theo. Thanks, @WangXiaoLab and @mbarnalab for the incredible support and guidance.
4
1,047
Huge congratulations, Xiao!
Congratulations to Xiao Wang (@WangXiaoLab), the Cabot Assistant Professor of Chemistry and a Core Member of @broadinstitute , who has been promoted to Associate Professor With Tenure, effective July 1, 2024. chemistry.mit.edu/chemistry-…
1
1
13
2,582
Congrats everyone!
54 graduates from the Chemistry Department received their advanced degrees and doctoral hoods yesterday! Congratulations to our newly minted PhDs and SMs! chemistry.mit.edu/chemistry-…
5
1,052
Thrilled (and a little late) to share that I’ve successfully defended my PhD thesis 🎓 My heartfelt thanks to my committee, mentors and everyone who supported me along the journey🥹
8
4
140
15,612
A moment of lab pride really makes my day😇
1
13
1,646
Congratulations Xiao!
Congratulations to Professor @WangXiaoLab, who has been honored as “Committed to Caring”. The Committed to Caring (C2C) program is a student-driven initiative that celebrates faculty members who have served as exceptional mentors to graduate students. chemistry.mit.edu/chemistry-…
6
1,644
Why can RNA only be linear or circular? It can be branched! We made multi-tailed mRNA, and we had fun! Here is our story led by brilliant graduate student @HongyuChenChem: rdcu.be/dB7ck and his cartoon illustration👇@ChemistryMIT @broadinstitute
Thrilled to see our work on chemically and topologically engineered mRNA online! Using a chemo-enzymatic approach, we introduced multiple end-modified polyA tails on a single mRNA to boost its stability and translatability overtime. nature.com/articles/s41587-0…
21
211
23
994
243,869
Such a well deserved honor for my amazing colleague. She is helping us see into the organization of cells in the brain and in modifying RNA to increase protein production!
Congratulations to @WangXiaoLab, who has been named a 2024 Sloan Research Fellow by @SloanFoundation! Fellows are chosen in recognition of their creativity, innovation, and research accomplishments. chemistry.mit.edu/chemistry-…
1
1
32
6,084
Deeply grateful to be awarded the @SchreiberStuart prize for scientific excellence at the 2023 @broadinstitute retreat. Huge thanks to my mentor @WangXiaoLab for unwavering support, to @ChemicalBiology for the gracious introduction, and to all brilliant minds in the Wang lab.
2
3
1
62
19,051
Photos credit to Erik Jacobs and our very own talented photographer @xsui98
1
1
1,852