Replying to @PriyamvadaGopal
Imagine thinking that word has any power at all anymore
Jonathan Anomaly retweeted
🚨🇺🇸🇮🇷 | ADVIERTEN SOBRE LA ALIANZA ENTRE LA IZQUIERDA Y EL ISLAMISMO: La médica iraní Sheila Nazarian recordó cómo marxistas y socialistas ayudaron a los islamistas a tomar el poder en Irán y terminaron perseguidos por el mismo régimen.
"En 1979, los islamistas se aliaron con los marxistas y socialistas. [...] Los izquierdistas creían que estaban utilizando a los islamistas. [...] Pero los islamistas los estaban utilizando a ellos. Y cuando dejaron de necesitarlos, se volvieron contra ellos. [...] Los estudiantes que ayudaron a llevar la revolución al poder fueron purgados, los profesores fueron purgados, los intelectuales encarcelados y los izquierdistas torturados y ejecutados".
Jonathan Anomaly retweeted
Maybe one of the most unforgettable surfing moments was captured by David Tereva.
[🏄♂️ terevadavid]
Replying to @catiamalinina
Yes, good question. It’s very unlikely that the kind of Asberger associated with a smart engineer is caused by these protein-truncating variants
Replying to @williameijer
I partly disagree: the lie is already *selective* blank slatism. Black athletes are allowed to be considered superior, and when Jared Diamond says that people from Papua New Guinea are probably smarter than Europeans, progressives nod in agreement. It’s a form of double think
Replying to @Babygravy9
To be fair, Netanyahu says the same thing for the English, the French, etc, so I’m not sure there’s a contradiction here
Jonathan Anomaly retweeted
“There will be no art, no literature, no science… There will be no distinction between beauty and ugliness. There will be no curiosity, no enjoyment of the process of life. All competing pleasures will be destroyed.”
Orwell, 1984
Replying to @cremieuxrecueil @NSesardic
Massively underrated book, full of incredible anecdotes
Embryo selection is one of the most interesting technologies out there. If you could choose your kid’s height, would you? What about intelligence? Or more saliently, the risk of key diseases that your kid might be predisposed to? And how do we even know the tech is real?
I discuss all this and more with @JonathanAnomaly , whose company @herasight is imputing polygenic risk scores for embryos based on fairly accessible inputs.
The quagmire of ethical and scientific questions all this presents, I think, is ultimately tractable and offers reason for optimism
Embryo selection and the science of creating future people with @JonathanAnomaly from @herasight
00:00 - From Academia to Herasight
07:12 - Is Embryo Selection Controversial
11:31 - Polygenic Scores Explained
21:14 - Why Insurance Hasn’t Covered It
28:18 - Who Uses Screening and Why
32:35 - IVF Limits and Future Tech
36:52 - Selection vs Editing and Gattaca Fears
42:07 - Ethical Boundaries
43:01 - Breakthrough Imputation Proof
48:49 - Winning Clinics Over
51:18 - Ethics Backlash Explained
55:28 - Preference Cascade Theory
59:19 - Blank Slate Debate
01:03:09 - Pleiotropy Tradeoffs
01:08:29 - Autism Risk Predictor
01:13:37 - Repro Tech And Birth Rates
01:20:17 - Relationships And Family Futures
01:24:25 -Books Recs
Replying to @TomlinsonCJ @SimoneHCollins
It prevents abortion: this occurs before any embryo is implanted
Jonathan Anomaly retweeted
Many people out there have grown up thinking they can't have kids as they're so worried about their family risk of conditions like schizophrenia.
That changes now. So cool.
Replying to @TeriSpe22509228 @_twolfram
Yes! Please feel free to read the paper or Substack summary for more on what we capture
Replying to @foothillsguy46 @_twolfram
Not abortion. This is for women who have to select an embryo blind or with information
Jonathan Anomaly retweeted

Aella@Aella_GirlOct 8
🇺🇸
United StatesConnected via United States Android AppAccount-level information, not a live location or per-post device.
I used NeuroRisk for genetic screening for myself, and found that I have a mutation in six3. This likely caused my brother's death shortly after birth, and gives ~25% risk of my own kids suffering the same.
I'll be using this info in my embryo selection!
Jonathan Anomaly retweeted
An important new innovation from Herasight: NeuroRisk.
NeuroRisk identifies embryos carrying damaging mutations in evolutionarily conserved genes, which increase risk for autism, schizophrenia, and other disorders - finding cases missed by polygenic scores and known genes.
Jonathan Anomaly retweeted

Crémieux@cremieuxrecueilOct 8
🇺🇸
United StatesConnected via United States Android AppAccount-level information, not a live location or per-post device.
Fascinating!
Embryo selection just keeps getting better because the predictors just keep improving all the time.
Now, just a handful of mutations = a large IQ and intellectual disability gradient to select on.













