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Parra

@JonathanParraV

Scientist ⚗️🔬. Ocean lover 🌊. Assistant Professor at @UniversidadCR 🌻. Research Associate at CENIBiot 🧬. #Bluesky 🦋 @jonathanparra.bsky.social

 Costa Rica
parralab.netlify.app/
Joined August 2018
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Photo by Parra (@JonathanParraV)Photo by Parra (@JonathanParraV)Photo by Parra (@JonathanParraV)Photo by Parra (@JonathanParraV)Photo by Parra (@JonathanParraV)Photo by Parra (@JonathanParraV)Photo by Parra (@JonathanParraV)Photo by Parra (@JonathanParraV)Photo by Parra (@JonathanParraV)Photo by Parra (@JonathanParraV)
Just in time for the holidays Convergent Evolution of the Antimycobacterial Lasso Peptide Triculamin biorxiv.org/content/10.1101/…
Convergent Evolution of the Antimycobacterial Lasso Peptide Triculamin

Convergent Evolution of the Antimycobacterial Lasso Peptide Triculamin

Triculamin is a ribosomally synthesized and post-translationally modified peptide (RiPP) lasso peptide with potent antimycobacterial activity, produced by an unusual, non-canonical biosynthetic gene...

biorxiv.org
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It was fantastic to have @BeaCamaraH presenting her work on antibiotic discovery from Chilean marine actinomycetes at the @UniversidadCR. Looking forward to collaborating.
Image from Parra (@JonathanParraV)
Image from Parra (@JonathanParraV)
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We are excited to announce our upcoming workshop designed to be interactive and beginner friendly. We will introduce Reverse Metabolomics, a novel approach to identifying microbial metabolites using mass spec. We will show YOU how to identify and categorize microbial metabolites!
Image from CMMC (@MicrobialCMMC)
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Very happy to introduce MS2DECIDE, a decision theory-based cheminformatics tools for NP prioritization from multiannotated MS/MS data. Have a look at our preprint @ChemRxiv rb.gy/1qn6c6 @LAMSADEDauphine @Paris_Dauphine @BioCIS @UnivParisSaclay
https://rb.gy/1qn6c6

ALT https://rb.gy/1qn6c6

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Metagenomic insights and biosynthetic potential of Candidatus Entotheonella symbiont associated with Halichondria marine sponges | Microbiology Spectrum journals.asm.org/doi/10.1128…
Metagenomic insights and biosynthetic potential of Candidatus Entotheonella symbiont associated...

Metagenomic insights and biosynthetic potential of Candidatus Entotheonella symbiont associated...

Our study reports the discovery of a new bacterial symbiont Ca. Entotheonella halido associated with the Korean marine sponge Halichondria dokdoensis. Using genome-resolved metagenomics, we recovered...

journals.asm.org
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I'm super proud of @DouglasAVenegas who represented our group at the V Latin American Metabolic Profiling Society Meeting. It's amazing to see a growing metabolomics community in Latin America. #VLAMPS @LampsNetwork
Image from Parra (@JonathanParraV)
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New pre-print from the group 🥳 We use targeted genome mining to show that the plant pathogen Rhodococcus fascians makes the antibiotic lydiamycin. The BGC information then informed the discovery of multiple key features relating to the molecule 1/4 biorxiv.org/cgi/content/shor…
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Emergency bulletin! 14 journals have co-published an urgent call for the deployment of microbial solutions against climate catastrophe, by @peixotors et al. nature.com/articles/s41564-0…
Image from Nature Microbiology (@NatureMicrobiol)
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The @HACforNP wins The Earthshot Prize to Revive Our Oceans for its powerful work pushing governments to follow through with their pledges to protect our oceans. Keep pushing, HAC! We are with you. #EarthshotCapeTown
Image from The Earthshot Prize (@EarthshotPrize)
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Congrats to @DavidRcoMark on publishing his PhD work! @Tucker303 @MicrobioSoc Chromosome architecture as a determinant for biosynthetic diversity in Micromonospora - go.shr.lc/4fwg5HU
Chromosome architecture as a determinant for biosynthetic diversity in Micromonospora

Chromosome architecture as a determinant for biosynthetic diversity in Micromonospora

microbiologyresearch.org
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The latest Microbe Profile on Pseudonocardia is now out in #MicrobioJ. Published #OpenAccess and fee-free using a #PublishAndRead agreement: doi.org/10.1099/mic.0.001501
Image from Microbiology Society (@MicrobioSoc)
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Lipidation Engineering in Daptomycin Biosynthesis | Journal of the American Chemical Society pubs.acs.org/doi/full/10.102…
Lipidation Engineering in Daptomycin Biosynthesis

Lipidation Engineering in Daptomycin Biosynthesis

Abstract. Lipopeptides are an important family of natural products, some of which are clinically used as antibiotics to treat multidrug-resistant pathogens

pubs.acs.org
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Pattern-based genome mining guides discovery of the antibiotic indanopyrrole A from a marine streptomycete biorxiv.org/content/10.1101/…
Pattern-based genome mining guides discovery of the antibiotic indanopyrrole A from a marine...

Pattern-based genome mining guides discovery of the antibiotic indanopyrrole A from a marine...

Terrestrial actinomycetes in the genus Streptomyces have long been recognized as prolific producers of small molecule natural products, including many clinically important antibiotics and cytotoxic...

biorxiv.org
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Join our free @mzmine_project webinar series together with VMOL. Starting off with mzmine 4 for #chromatography #LCMS #massspectrometry #CompMS #metabolomics. November 5th (next Tuesday) Register with VMOL to receive updates and the zoom link: docs.google.com/forms/d/e/1F…
Image from Robin Schmid (@rschmid1789)
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Invasive fungal infections kill 3.8 millions of deaths annually. Current antifungal medicines are limited by toxicity, drug-drug interactions and resistance. We report alligamycin as a novel antifungal lead against resistant Aspergillus and Talaromyces. nature.com/articles/s41467-0…
Alligamycin A, an antifungal β-lactone spiroketal macrolide from Streptomyces iranensis

Alligamycin A, an antifungal β-lactone spiroketal macrolide from Streptomyces iranensis

Nature Communications - From the rapamycin-producer Streptomyces iranensis, authors report on the discovery of the antifungal candidate alligamycin A, which exhibited strong activities against...

nature.com
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We are pleased to announce our upcoming mzmine webinar series in collaboration with VMOL. This series will focus on various aspects of mass spectrometry data processing, showcasing the capabilities of mzmine. Sign up for free!
Image from mzmine (@mzmine_project)
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Pseudonocardia: antibiotics for every niche. Published #OpenAccess and fee-free in #MicrobioJ using a #PublishAndRead agreement as part of the Microbe Profiles collection: doi.org/10.1099/mic.0.001501
Image from Microbiology Society (@MicrobioSoc)
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Encantada de compartir mi experiencia dentro del maravilloso mundo de las actinos 👩‍🔬🦠
Red Académica y Científica de Colombia en México (@REDACOLMEX) profile pictureRed Académica y Científica de Colombia en México@REDACOLMEX15 Oct 2024
🧪El #NodoAgricultura invita a participar en el #Webinar "Explorando el potencial biosintético de actinobacterias ambientales: sinergia entre bioinformática y biología sintética" con la maestra Luz A. González 📅22 oct ⏳1pm🇲🇽| 2pm🇨🇴 Enlace Zoom ➡️bit.ly/48lZEvD
https://www.redacademicaycientifica.org/eventos/webinar-potencial-biosintetico-de-actinobacterias/

ALT https://www.redacademicaycientifica.org/eventos/webinar-potencial-biosintetico-de-actinobacterias/

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Academia be like
Terrible Maps (@TerribleMaps) profile pictureTerrible Maps
@TerribleMaps16 Nov 2023
The international community
Image from Terrible Maps (@TerribleMaps)
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16S rRNA phylogeny and clustering is not a reliable proxy for genome-based taxonomy in Streptomyces. . Published #OpenAccess and fee-free in #MGen using a #PublishAndRead agreement: doi.org/10.1099/mgen.0.00128…
16S rRNA phylogeny and clustering is not a reliable proxy for genome-based taxonomy in Streptomyces

16S rRNA phylogeny and clustering is not a reliable proxy for genome-based taxonomy in Streptomyces

microbiologyresearch.org
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