We make stuff up for living || Chromatin || Transcription || Epigenetics

Research Triangle Park, North Carolina, …
Joined September 2018
A fascinating close up of how a bee stinger works 📹 Stated Clearly xitter.cf/blabla112345/status/16…
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Confused by all the "what is epigenetics" discourse? Well I have just the thing for you -- presenting the Epigenetics Alignment Chart!
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What role does the bivalent chromatin play in differentiating stem cells? Dr Dhirendra Kumar from @Jothi_Lab will join us next Monday to present his latest research on the regulatory role of bivalency in maintaining epigenetic plasticity. Joins via zoom. No registration required.
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My Department at Thomas Jefferson Univ is hiring a new Assistant Prof. (ad coming soon) in any area of Molecular Biology and Biochemistry! It’s a great Department full of nice people with a lot of collaboration opportunities. DM if you have any question and please RT!
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The Banaszynski lab is hiring a postdoc! We are a chromatin lab studying histone variant biology in the context of both development and disease. Help me spread the word and message me if you are interested. 1/
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This figure is insane. The extreme underrepresentation of z-values between -2 and 2 (which is just around the commonly used p-value threshold of 0.05) demonstrates publication bias/p-hacking/etc. Sharp edge near the threshold. Source: arxiv.org/abs/2009.09440
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Spectacular
Doron
@plexaleOK12 Nov 2020
Esto es maravilloso
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We have a 3-yr benchwork (wet lab) research officer position open. This position is jointly mentored by Prof. Patrick Tam and me. For more details: seek.com.au/job/50568775?typ…
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Integrator brings PP2A to Paused Pol For termination #ChromatinHaiku cell.com/molecular-cell/full…
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Our contribution to understand the role of the Polycomb-associated factor PHF19 in controlling hematopoietic stem cell state and differentiation advances.sciencemag.org/cont…
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Replying to @PengyiYang82
Congratulations all!!
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Putting multiple post-docs on the same project
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Jothi Lab retweeted
"Evaluating Enhancer Function and Transcription"! Great to see this now out - A fantastic review on enhancer function and txn from @AFieldNote and @AdelmanLab! annualreviews.org/doi/abs/10…
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Zhang,@realzhang, Xiong, Zhu and co show that, although H3K27ac is used as a marker for active enhancers, you can remove it from mESCs and enhancers still function with little alteration to the transcriptome. genomebiology.biomedcentral.…
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Jothi Lab retweeted
Planning a Hi-C experiment? Have a look at our AI predicting 3D contacts based on epigenetic data first! We released the web-version genedev.bionet.nsc.ru/Web_3D…, so you can get an idea about @3D_Genome and @generegulation before starting experiment! More info: genome.cshlp.org/content/ear…
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Kudos to @HainerLab for capturing the works presentated at #KSgene and #KScancerepigenetics!
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This is crazy! 3.7 Å.
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Online Now: PRC1 Catalytic Activity Is Central to Polycomb System Function dlvr.it/RLzV4G