Doing behavioral neuropharmacology in OKC. Trying to outsmart young and old mice and determine circuitry modulating feeding, cognition, and reward.
Joined November 2018
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SharpeLab retweeted
Thunder fans, this is your chance to win one of these team-signed jerseys right in time for the Playoffs! 🎉
Here's how to enter:
- Like & reshare this post
- Comment with a Thunder GIF
SharpeLab retweeted
Hyperexcitable VTA dopamine neurons in an AD mouse model?! Check out our latest preprint where we use Patch-seq to ID a single enzyme & target it to restore normal firing. Work led by PhD student @HarrisEdwardB; big shouts to @LabSharpe @FreemanLabOMRF
doi.org/10.1101/2023.11.16.5…
SharpeLab retweeted
We had a great time today at the #Walk2EndAlz! Thank you to everyone who joined GSA-OK in participating in this big event! More photos to come 😊
SharpeLab retweeted
Impressive tour this wk of @OMRF in celebration of 77 years of innovation & service to Oklahoma. Through critical research on curing diseases such as multiple sclerosis, heart disease, & cancer, these scientists have helped people around the world live healthier lives. #OkieProud
SharpeLab retweeted
Lots of good news from the Ocanas Lab! We just received a $248,000 grant from the @alzassociation to study estrogenic effects in Alzheimer’s disease. @alzoklahoma
With a new grant from @alzassociation, OMRF's Dr. Sarah Ocañas (@OcanasSR) is studying whether an estrogen boost can delay or possibly prevent Alzheimer's disease in post-menopausal women ⤵️ omrf.org/2023/10/17/omrf-sci…
SharpeLab retweeted
Check out this excellent program through @ASPET for early career pharmacologists interested in gaining science policy and advocacy experience!
Are you an early-career scientist interested in #sciencepolicy? Applications for the 2024 ASPET Washington Fellows program begin August 1, 2023. Become a #scienceadvocate by learning about the pressing issues impacting science today. Learn more here: bit.ly/3HsbDto.
SharpeLab retweeted
Congrats to the @FreemanLabOMRF for a great report on MHC-I induction in the brain during aging and Alzheimer's disease! @AM_OMRF @OMRF
📢New Paper📖Alert
Microglial MHC-I induction with aging and Alzheimer’s is conserved in mouse models and humans by Collyn M. Kellogg et al.
link.springer.com/article/10…
@OMRF @OUResearch @FreemanLabOMRF
#neuroinflammation #aging #alzheimers #microglia #senescence #immune #antigen
SharpeLab retweeted
I’m very honored to have received the Graduate Student Association Award for Scientific Achievement at the 2023 GREAT Symposium! Thank you @OcanasSR for being such an outstanding mentor and guiding me through every step of this insightful process!
SharpeLab retweeted
This week, Dr. Rod McEver marks a pair of major milestones: Today, he’s celebrating his 75th birthday.
And tomorrow, after 35 years as a scientist, program chair, and vice president of research at OMRF, will be his first day of retirement! 🥳omrf.org/2023/03/05/a-retire…
SharpeLab retweeted
I am very excited about my new publication on methamphetamine self-administration, mitochondrial function, and dopamine neurotransmission! doi.org/10.1016/j.neuropharm…
SharpeLab retweeted
Shout out to @evastc, @HarrisEdwardB & @kyhonda for our latest aging/physiology study now out in @SciReports! Old (>20 mo) male mice have smaller D2-GIRK currents in the nigra than young mice, but remarkably aging DOESN’T affect most local DA physiology 👀 rdcu.be/c3LyI
SharpeLab retweeted
Congratulations to Harris Blankenship (@HarrisEdwardB) of the Beckstead lab (@mjbeckstead). Harris is an all star student and just passed his general exam in the Dept. of Physiology at OUHSC. Great job, Harris! @OUHSC_GPiBS
SharpeLab retweeted
Come visit us in OKC for the 2023 Geroscience Symposium. Travel awards are available!! @GeroScienceAGE @americanaging @AM_OMRF @NathanShockCtrs
We will grant Travel Awards for the 2023 Geroscience Symposium. Awards will cover the cost of airfare, 2 nights stay, and local transportation. Submissions will be accepted beginning January 1, 2023 through buff.ly/3G3sfZT .
SharpeLab retweeted
Bittersweet reads. My crusty generation has failed gen Z. $2k in award winnings doesn’t offset the fact that these kids should have never had the cause to write these words. Proud of, but so sorry for, my baby girl. marchforourlives.com/jat-wri…
SharpeLab retweeted
Thrilled to see our work out in @SfNJournals! Dopamine neurons release neurotensin to cause LTD of dendritic D2-IPSCs, but only in nigra and not VTA. Optostim of DA cells can both evoke IPSCs and cause LTD that is dependent on NTS receptors and... 1/2
jneurosci.org/content/42/32/…
SharpeLab retweeted
Abbott chose to let it happen again. And again and again.
Editorial: Abbott says 'never again' after Uvalde school massacre. Don’t fall for it, Texans. bit.ly/3LM5323
SharpeLab retweeted
If it could get any more ridiculous, consider this: No one uses the Sudafed (pseudoephedrine) route to make methamphetamine anymore, it's exclusively P2P (phenyl-2-propanone), and has been for a decade. We could lift the restriction today and it wouldn't affect meth synthesis.
This Post is from an account that no longer exists. Learn more
SharpeLab retweeted
We know common sense gun laws can’t and won’t prevent every tragedy. But we know they work and have a positive impact.
When we passed the assault weapons ban — mass shootings went down.
When the law expired — mass shootings tripled.
