@LabVogeli

NMR spectroscopy for the elucidation of conformation and communication networks within and between proteins and nucleic acids. University of Colorado, USA

 Colorado, USA
ncbi.nlm.nih.gov/myncbi/vogeli.lab.1/bibliography/public/
Joined July 2019
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  • Following269
  • Followers402
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New paper from our lab Cromolyn, an #FDA-approved drug, binds selectively to ADAR1p150—revealing a new pharmacophore to tune #RNA editing & immune signaling in #Cancer. @CUCancerCenter @CU_BMG Collab w/ Rincon & Quentin Vicens labs @qvicens @LabVogeli onlinelibrary.wiley.com/doi/…

Cromolyn as a novel pharmacophore of the Zα domain of the RNA‐editing enzyme ADAR1p150

ADAR1p150 is a critical RNA-editing enzyme for maintaining cellular homeostasis through dsRNA binding, protein–protein interactions, and adenosine-to-inosine (A-to-I) editing. Beyond its dsRNA...

onlinelibrary.wiley.com
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One of the largest study to characterize metabolites in ultramarathon runners. A great effort and amazing contributions from runners. #runrabbitrun @travisnemkov @dalessandrolab @CU_BMG @CUAnschutz
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Quentin Vicens@qvicens16 Jul 2024
Novel Z-DNA binding domains in giant viruses - great collaboration with @LabVogeli and Mamadou Diallo now published @jbiolchem @UH_NSM sciencedirect.com/science/ar…
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Replying to @ReidAlderson
@ReidAlderson gave a fantastic talk about tackling IDRs by AF2 and methyl-TROSY today. So inspiring. Nice to see John Markley, Beat Vogeli and Morkos Henen together, too. #NMRchat #StructuralBiology @HelmholtzMunich @CUDenver @LabVogeli @CUAnschutz
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Vögeli_Lab retweeted
Quentin Vicens@qvicens29 Aug 2023
Free registrations now open for ABZ2023 - virtual on Nov 28 abz.bio/ @LabVogeli @insideoutbio

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In contrast to the common right-handed A- and B-conformations of RNA and DNA, their Z-conformations are left-handed. Starting with the crystallization of Z-DNA in 1979, biophysical and biochemical...

abz.bio
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Jeff Chan@profjeffchan26 May 2023
Amazing time at @CUAnschutz for the Structural Biology and Biochemistry Symposium. Special thx to the student organizing committee for the invitation. The STBB program is phenomenal! Pic w Abby, Anna, Ian, @jeffrey_krall @kilsiologia @LabVogeli @dschweppe1 & Prof Brüschweiler
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Happy to share our most recent work with @EmilyDykhuizen lab on the binding of PBRM1 bromodomains to RNA. As always a super fun collaboration! Led by @DsdSaumi and @DrDhimanA with contributions from @Surbhi__Sood @kilsiologia @morkos_henen @LabVogeli academic.oup.com/nar/advance…

PBRM1 bromodomains associate with RNA to facilitate chromatin association

Abstract. PBRM1 is a subunit of the PBAF chromatin remodeling complex, which is mutated in 40–50% of clear cell renal cell carcinoma patients. It is though

academic.oup.com
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Meet Natasia Paukovich (@natasiainthelab) 🤩 She is a 4th year PhD student in the @LabVogeli and @molbcu 🧬
SACNAS at CU Anschutz@SACNAS_CUA4 Oct 2022
Replying to @SACNAS_CUA
Our excitement is growing as we approach the date, and we are eager to maximize the experience for our chapter members. With that said, we will be giving shout outs to members from our chapter who will be at the conference.
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Vögeli_Lab retweeted
Quentin Vicens@qvicens8 Sep 2022
ESKAPE Pathogens! The second paper published in this special Topic @MDPIOpenAccess on 'Emerging aspects in drug discovery' mdpi.com/1820838 #mdpiantibiotics @antibioticsmdpi @LabVogeli @morkos_henen

ESKAPE Pathogens: Looking at Clp ATPases as Potential Drug Targets

Bacterial antibiotic resistance is rapidly growing globally and poses a severe health threat as the number of multidrug resistant (MDR) and extensively drug-resistant (XDR) bacteria increases. The...

mdpi.com
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Vögeli_Lab retweeted
Quentin Vicens@qvicens7 Sep 2022
Dr. Yukio Kawahara from @osaka_univ_e kicking off our part 2 of the ABZ2022 meeting on the Z-form of nucleic acids! With @LabVogeli @insideoutbio and many more... @Molecules_MDPI @RNASociety @IJMS_MDPI
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Quentin Vicens@qvicens18 Aug 2022
First paper published in the special Topic series on Emerging aspects in drug discovery! Consider submitting yours @morkos_henen @LabVogeli @MDPIOpenAccess @Molecules_MDPI mdpi.com/topics/emerging_dru…

Emerging Aspects in Drug Discovery | MDPI

With the large number of diseases still present worldwide that remain difficult to treat, drug discovery is a pressing endeavor. However, finding effective...

mdpi.com
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More exciting #Drug_Discovery research in this topic we are editing @qvicens @LabVogeli @CUAnschutz
IJMS MDPI@IJMS_MDPI20 Jun 2022
Dr. Morkos Henen, Dr. Quentin Vicens and Dr. Beat Rolf Vögeli are leading this Topic "Emerging Aspects in Drug Discovery" for us together, please check the website: mdpi.com/topics/emerging_dru… and submit your publications! @CCTSI
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We are editing a new topic in @MDPIOpenAccess about "Emerging Aspects in Drug Discovery". This will include 5 journals such as @Molecules_MDPI and @Magnetochem Submissions are now accepted @qvicens @LabVogeli #drug_discovery mdpi.com/topics/emerging_dru…
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Very excited to share the latest work by @DsdSaumi! Another super fun collaboration with @EmilyDykhuizen lab. @Surbhi__Sood @DrDhimanA @kilsiologia @LabVogeli @morkos_henen @CUAnschutz @IowaBiochem @Purdue_MCMP biorxiv.org/content/10.1101/…

PBRM1 BD2 and BD4 associate with RNA to facilitate chromatin association

PBRM1 is a subunit of the PBAF chromatin remodeling complex, which is mutated in 40-50% of clear cell renal cell carcinoma patients. It is thought to largely function as a chromatin binding subunit...

biorxiv.org
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Announcing IVEM seminar on November 18, 9 pm New York time by Alexandra Born. Interested audience please sign up at forms.gle/Usv8sbj3LUr7QvcE8 to become an IVEM speaker and receive notice of future IVEM activities.
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And it’s officially out😊. #NMR #drug_discovery @CUAnschutz @CUCancerCenter Microbiota-derived butyrate is an endogenous HIF prolyl hydroxylase inhibitor tandfonline.com/doi/full/10.…
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Vögeli_Lab retweeted
Quentin Vicens@qvicens8 Apr 2021
Co-organizer of the ABZ2021 Meeting on May 19th with @LabVogeli and co. Free registration! abz2021.bio
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Vögeli_Lab retweeted
Natasia@natasiainthelab9 Jan 2021
It’s been a long week. Year? @LabVogeli #nmr #sciencehumor
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Vögeli_Lab retweeted
Hansen Lab@ecmatlas8 Nov 2019
Congratulations to our grad student Max for passing his Comprehensive Exam this afternoon! Time to celebrate! #ecm #predoctoralcandidate
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