All views solely of Dr. Lamming and do not necessarily reflect views of my employers, funders, or societies. Retweet≠Endorsement. @LammingLab@fediscience.org
Wisconsin, USA
Joined April 2015
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Very cool story from @WiscoSurgMetab about the surprisingly protective effects of sleeve gastrectomy on the development and progression of Alzheimer’s disease in a mouse model! Glad to have been able to assist with this project.
It is hard to imagine that cutting away a portion of the stomach could prevent future Alzheimer’s Disease but here, in our first of many stories to come, we show just that! SG’s effects on the brain are profound and long lasting! @LammingLab @WiscSurgery
onlinelibrary.wiley.com/doi/…
Lamming Lab retweeted
It is hard to imagine that cutting away a portion of the stomach could prevent future Alzheimer’s Disease but here, in our first of many stories to come, we show just that! SG’s effects on the brain are profound and long lasting! @LammingLab @WiscSurgery
onlinelibrary.wiley.com/doi/…
An amazing first step on the road to repair and rejuvenation!
Breaking
lifespan.com/blogs/magazine/…
Lamming Lab retweeted
Please spread the word on hiring in our department. We are searching broadly but particularly interested in Systems and Synthetic Biology. I am chairing this faculty search, please feel free to reach out if you have any questions.
Deadline Oct. 15: We are hiring for a professor at any level to join our creative and dynamic community. Candidates in all areas of #biochemistry will be considered, and we are particularly interested in candidates in systems and synthetic biology. jobs.wisc.edu/jobs/assistant…
ALT Poster for job ad. Read further details at jobs.wisc.edu. Job number JR10012489.
Lamming Lab retweeted
1. We’re excited to share our latest paper, “Decline of chaperone-mediated autophagy (CMA) in aging impairs macrophage clearance of senescent cells” published
in @NatureAging led by @Beccasereda is now out! nature.com/articles/s43587-0…
Lamming Lab retweeted
Why do muscle fibres shrink with age?
Not because myofibrils get smaller — because there are fewer of them.
We followed this from whole-muscle down to individual myofibrils, in humans and mice, across ageing and disuse.
Tweetorial below
Open Access here: physoc.onlinelibrary.wiley.c…
1/ Why do muscles atrophy with aging and disuse?
Is it because each tiny little myofibril gets smaller… or is it because we lose myofibrils?
In our new study, we addressed this in humans and mice. biorxiv.org/cgi/content/shor…
Full breakdown of the findings in this thread 👇
Check out the latest pre-print from our lab, the work of star graduate student @mmsonsalla! If you (a mouse who is extremely online) reduces dietary protein and increase dietary carbohydrates, does it matter what type of carbohydrates you are eating? Find out from our paper:
For those who are wondering about the human relevance of our BCAA work, a new paper showing dietary BCAAs are associated with plasma BCAAs and plasma BCAAs are associated with multiple Cardiometabolic risk factors
What an exciting story!
Excited to share our new study, spearheaded by talented former graduate student Kübra B. Akkaya-Colak!
Stearoyl-CoA desaturases regulate intestinal stem and progenitor cell metabolism and function in response to nutrient abundance: Cell Reports cell.com/cell-reports/fullte…
Lamming Lab retweeted
Excited to share our new study, spearheaded by talented former graduate student Kübra B. Akkaya-Colak!
Stearoyl-CoA desaturases regulate intestinal stem and progenitor cell metabolism and function in response to nutrient abundance: Cell Reports cell.com/cell-reports/fullte…
Lamming Lab retweeted
Profound and heartfelt thanks to the over 100 contributors who made this epic 3-volume, >1600 pages landmark academic treatment of aging biology, longevity therapeutics, and the science, technology, and policy of life extension possible, including @NirBarzilaiMD, @sjayolshansky, @biogerontology, @davidasinclair, @j_n_justice, @RaianyRomanni, @drmichaellevin, @ydeigin, @aubreydegrey, @TinaWoods, @JamesPeyer, @Danbelsky, @Dr_Bischof, @LidskyPeter, @MarkHamalainen, @DToddWhite, @marcpbernegger, @MattYousefzadeh, @M_S_Ringel, @LeeYuta45307, @HeWei16027, @DrGlorioso, @AnmolMD, @adamgries, @gblander1, @ProfValterLongo, @LammingLab, @DomiWilczok, @LPiolopez, @pgerwill, @KarlPfleger, @BernardSiegel, @Yu_Xuan_Lu, @Rcmsiow, @cordeiro, @Scinquisitor, @TinkingGumbel, @romanbauer111, @KeithComito, @soniaarrison, and many more.
Special thanks to my fellow Co-Editors, @MaxRangeley, Regina Monaco, and David Wood (@dw2), whose intellectual leadership, editorial rigor, and sustained commitment helped transform an ambitious vision into a coherent three-volume landmark work. It was a privilege to shape this project alongside them.👨⚕️
Another great discussion of protein in Scientific American @sciam scientificamerican.com/artic… - with a mention of @mariahcalubag recent valine restriction paper as well!
Great discussion of dietary protein and aging in @ScienceNews today "The protein craze may not be for everyone", spurred in part by @baileyknopf 's new review article entitled "The hallmarks of protein and amino acid restriction in aging and longevity"
Great discussion of dietary protein and aging in @ScienceNews today "The protein craze may not be for everyone", spurred in part by @baileyknopf 's new review article entitled "The hallmarks of protein and amino acid restriction in aging and longevity"
Here's a direct link to the open access review in @cellpressblue cell.com/cell-press-blue/ful…
Lamming Lab retweeted
Branched chain aminos (e.g. leucine & valine) help build muscle but also activate mTOR. Here, Lamming & team report that restricting valine extends the lifespan of male mice 23%, indicating high protein diets deserve scrutiny from a longevity perspective 🐭
I am delighted to be able to share the latest study from the @LammingLab, “Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in mice” led by former graduate student @mariahcalubag!
Lamming Lab retweeted
Valine restriction improves metabolic health in mice, promotes leanness and glycemic control across ages, and reduces frailty, cancer prevalence and senescent cell burden in both sexes while increasing median male lifespan by 23%.
By @LammingLab et al. #DR
nature.com/articles/s43587-0…
Lamming Lab retweeted
I am delighted to be able to share the latest study from the @LammingLab, “Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in mice” led by former graduate student @mariahcalubag!
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