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New publication alert! We predict immunotherapy outcome from gut microbiome using a novel gut-on-a-chip model, providing novel mechanistic insights on immunoregulatory interactions taking place in the gut and impacting systemically.
nature.com/articles/s41551-0…
It was a long and bumpy journey, but I am glad to share that our study is now online on Cell Press Cell Host and Microbe!
sciencedirect.com/science/ar…
We discovered and validate that antigen-tumor mimicry is relevant for response to immunotherapy in melanoma patients, revealing the cross-cohort prognostic value of microbial-based features while providing unprecedented insights on gut microbiota dynamics.
Congratulations to the whole Team and thanks to @IEOufficiale and our funding agencies @AIRC_it @WorldwideCancer for supporting our lab!
Luigi Nezi retweeted
The lab is recruiting (postdoc level) 👇 Join us: we love good science and there is a great team spirit 💫 clavel.ukaachen.de; ukaachen.de/stellenangebote/…
Getting close, please register, spread, donate!
#FondazioneIeoMonzino - LA RICERCA È NELL'ARIA partecipa.fondazioneieomonzi…
Ride your bike for cancer research!
#FondazioneIeoMonzino - LA RICERCA È NELL'ARIA partecipa.fondazioneieomonzi…
Luigi Nezi retweeted
Happy to announce that our recent adipocyte-cancer cell interaction paper is online. We describe a metabolic adaptation of metastatic ovarian tumors to colonize the adipose tissue.
Online now! Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis dlvr.it/SvQ7xb
Luigi Nezi retweeted
Cracking cancer w/engineered skin commensals. @GalieSerena @Lunezi discuss work of @yerinchen @mfgrp @ScienceMagazine proposing engineering of commensal bacterium of skin #microbiota to cross-present tumor antigens to #Tcells &counteract tumor progression cell.com/cell-host-microbe/f…
Luigi Nezi retweeted
@lunezi demonstrated the gut #microbiota is distinct in patients with complete ICB response
#EACR2023
Luigi Nezi retweeted
Very happy to announce our latest paper in @GenomeMedicine on the link between microbiome composition and colon cancer properties (molecular and clinical): doi.org/10.1186/s13073-023-0…. A thread
Luigi Nezi retweeted
This was an exciting collaboration across labs and fields (here on twitter: @Lunezi, @ZellerGroup, @JakobWirbel, @CarlottaCatozzi, @TizianoDallavi1). Congrats in particular to Gaia (@sam_ga9) who spearheaded this project.
Luigi Nezi retweeted
New! Online now: Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity dlvr.it/Skq8kz
Luigi Nezi retweeted
"The person-to-person transmission landscape of the gut and oral microbiomes". Our work on microbiome stransmission published today open-access in @Nature! Fantastic work @MireiaVallesc, the whole @cibiocm group @CIBIO_UniTrento and all the collaborators! nature.com/articles/s41586-0…
Luigi Nezi retweeted
Multiple open positions in my lab!
Please re-tweet and get in touch with me for any questions! Other positions will appear, looking for enthusiastic candidates not necessarily experienced in metagenomes as long as they have solid computational or quantitative background!
Luigi Nezi retweeted
Oxygen levels at the time of activation determine T cell persistence and immunotherapeutic efficacy biorxiv.org/cgi/content/shor… #biorxiv_immuno