Philadelphia, PA
Joined March 2013
- Tweets193
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- Followers283
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Happy to be able to show some love to 🐟 gills, which I've really enjoyed learning about over the past two years.
Excited to share the final publication soon! 🤞
Really appreciated this opportunity from @the_Node to write about the amazing journey I got to be on for 6 years and the people I met on the way.
Every day I feel fortunate to live in and work for a society that chooses to be curious. I hope it continues to do so. ✨
Fish, Frogs, Friends, Lend me your Ears. 🐟🐸🐁🦎
Read this 'Behind the paper' story from @MathiThiru95 about her PhD work with @CrumpLab:
thenode.biologists.com/fish-…
#DevBio #EvoDevo
Mathi Thiruppathy retweeted
Here is the 2025 embryo alphabet from alligator to zebrafish. Developmental biology is stunning & leads to important discoveries for human medicine. @SocDevBio @NIH @NSF
Mathi Thiruppathy retweeted
Nice article in Scientific American about our work on outer ear evolution and a complimentary study from the lab of Maksim Plikus on role of unique lipids in mammalian ear cartilage. @MathiThiru95 @USCStemCell @KECKSchool_USC
scientificamerican.com/artic…
Mathi Thiruppathy retweeted
Sox10 is required for systemic initiation of bone mineralization
Read this Research Article by Stefani Gjorcheska, Lindsey Barske and colleagues @CincyResearch:
journals.biologists.com/dev/…
ALT Figure 1 (A) Example images illustrating a major delay in initiation of bone mineralization in sox10 mutants between 3 and 7 dpf revealed by Alizarin Red staining. Some mineralization is present by 5 dpf but never achieves control levels before lethality at 8 dpf.
Mathi Thiruppathy retweeted
Excited to share our new publication, “Bidirectional histone monoaminylation dynamics regulate neural rhythmicity;” a massive collaboration across 5 labs (@Yael_David__ @MuirLab @SimoneSidoli and Haitao Li) See 🧵 below for the highlights nature.com/articles/s41586-0…
Mathi Thiruppathy retweeted
You can view the PDF of our gills to outer ears paper here: rdcu.be/d5Ml5
Also the link to the article on Nature is now working again: nature.com/articles/s41586-0…
Mathi Thiruppathy retweeted
Welcome to embryo alphabet. Each day I will post an unannotated embryo image. Today E is for elephant. Repost tweet w/an image of a different species embryo & add a quote including name that begins with same letter of the day. @SocDevBio
ALT African elephant fetus. bit.ly/4fIMTx1
Excited to share this story from my PhD revealing the surprising legacy of our gill-bearing ancestry in the form of our cartilaginous outer ears, summarized in this series of Tweets.
The outer ear is a mammalian innovation but where did it come from? In our study in @Nature, @MathiThiru95 and colleagues find that the outer ear arose from modification of an ancestral gill program first originating in marine invertebrates. nature.com/articles/s41586-0…
1/n
Thank you to all co-authors! @GillisLab @EvseenkoLab @YaWenChenMSSM @goodfrognosis and everyone not on Twitter/X. It's hard to emphasize how amazing it's been to work with people of such diverse expertise who still had an interest in various obscure aspects of this work.
Thanks especially to @CrumpLab for providing the opportunity to do exciting, diverse experiments, as well as the necessary guidance and confidence!
Mathi Thiruppathy retweeted
An @USCStemCell study published in @PNASnews has identified gene regulators that enable fish and lizards to naturally regenerate their hearing. The findings could guide future efforts to regenerate hearing for patients. @CrumpLab @KeckSchool_USC stemcell.keck.usc.edu/study-…
Mathi Thiruppathy retweeted
🎉 We're excited to share our new research in @Nature! We reveal that crocodile head scales self-organize through compressive folding of the skin - a mechanical twist on their development & evolution!
Please read & share 🐊🔬 @genevunige @UNIGEnews
nature.com/articles/s41586-0…
Mathi Thiruppathy retweeted
Nature research paper: Adipose tissue retains an epigenetic memory of obesity after weight loss go.nature.com/4eJizC8
Mathi Thiruppathy retweeted
Embryology: Concepts and Techniques in Modern Developmental Biology 🧫 🧬 🔬 🦠
June 1 – July 15, 2025
Deadline: January 22, 2025
go.mbl.edu/embryology
ALT Embryology Advanced Research Training Course postcard
Mathi Thiruppathy retweeted
Do you love evo-devo and want to do a PhD on millipede trachea homology in beautiful Vancouver 🇨🇦?
Come join my lab! form.jotform.com/24253453786…
Please re-tweet :)
Mathi Thiruppathy retweeted
Our paper ‘Whole-embryo Spatial Transcriptomics at Subcellular Resolution from Gastrulation to Organogenesis’ is now on biorxiv! We introduce weMERFISH, a platform for profiling gene expression in entire embryos at subcellular resolution. Here is🧵biorxiv.org/content/10.1101/… (1/12)
Excited to start my postdoc in @kamberovlab at UPenn studying the development and evolution of eccrine sweat glands and human thermoregulation. Thanks to all my new lab mates for the warm welcome. 😃
Mathi Thiruppathy retweeted
Pathway to Independence – an interview with Marcella Birtele
@MarcellaBirtele, one of our PI Fellows, talks about how the research questions she hopes to address with her own lab will bridge her previous neurodegeneration and neural development studies:
journals.biologists.com/dev/…
ALT Photo of Marcella Birtele
Mathi Thiruppathy retweeted
Vasculature of adult zebrafish gills. Credit to Dr. Madina Wane. #ZebrafishZunday
ALT Cross section of adult zebrafish gills with vasculature in blue and cell nuclei in purple
Mathi Thiruppathy retweeted
What if you could deliver molecular tools directly into oocytes without microinjection? In our new paper, online today @Dev_journal (doi.org/10.1242/dev.202857), we introduce VitelloTag, a new cargo delivery tool to enable injection-free genome editing. 👇Read on for a short 🧵
