Man of Science 🧬 AI & Gerophysics to understand Aging. 🇸🇬 Rethinking the Fundamentals of Aging & Rejuvenation Biology @TTIScience 🇺🇸

Singapore & Europe
Joined October 2018
Erst kamen sie für die Synagogen. Dann für die Kirchen. And zuletzt für die Universitäten.
Heute ist der erste Tag seit Jahrhunderten, an dem Soldaten in Europa unsere Kirchen, unser christliches Erbe vor den Horden des Islamismus schützen müssen. Das waren Angela Merkel und die zerstörerische EU-Ideologie der offenen Grenzen.
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Would be cool to see that Roman Catholic Religious Orders like the Teutonic Order, the Equestrian Order of the Holy Sepulchre, or the Sovereign Military Order of Malta take an active interest in longevity science and medicine.
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Hinton got it wrong. It’s actually okay if it has the desire and wants to kill you. It just must not be able to kill you. In the case of the tiger this means chaining it, pulling its teeth, and taking off its claws.
Hinton is giving the Gödel lecture at TU Wien and this is our current state according to him:
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Max Unfried retweeted
I’m convinced 95% of being a high performer is to just do 5 things: - Be obsessed like a psychopath - Have delusional optimism - Avoid unserious people - Take asymmetric risks - Be relentless
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Hope we will also get war mammoths to secure land border, and war whales to secure sea borders.
JUST IN: Palmer Luckey's genetically modified military dog startup, Warhound, comes out of stealth, aiming to create enhanced canines for the U.S. military.
Readers added context they thought people might want to know
This is NOT Palmer's company at all, his company Anduril is only supplying the tech for the dogs, and this is a wholly owed Collosal entiity x.com/palmerluckey/s…
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It’s a great day for science without boundary. At any given time in civilizational history we should fully lean into what science is capable in accomplishing. The markets then will price it accordingly and and see if it’s wanted.
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Max Unfried retweeted
Fantastic Junior Group leader position at the Curie Institute in Paris!! Areas of interest include stem cells, tissue growth and morphogenesis, epigenetics, genomics, integrated physiology, metabolism, and synthetic embryo models. Please RT! jpi-recruitment-curie-umr321…
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Enhanced animals are a pretty good start to get to enhanced humans.
JUST IN: Palmer Luckey's genetically modified military dog startup, Warhound, comes out of stealth, aiming to create enhanced canines for the U.S. military.
Readers added context they thought people might want to know
This is NOT Palmer's company at all, his company Anduril is only supplying the tech for the dogs, and this is a wholly owed Collosal entiity x.com/palmerluckey/s…
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A homeless person and a rich person have more in common with each other than with the normies.
the rich and poor have free time. everyone else is at work
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Max Unfried retweeted
Now can self custody your startup. We are live.
Obolos is LIVE on mainnet! We’re building the capital coordination layer for agents and humans. One protocol bringing together cap tables, fundraising, shareholder management and equity workflows, from pre-seed to pre-IPO. Here’s how it works 🧵 Built on @arbitrum and @fhenix.
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If you're in town worth checking out if you're interested in longevity and jurisdictions that try to accelerate progress!
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One codon-level therapy can hit nonsense mutations shared across multiple aging diseases. Brian Bodemann (ARTAN Bio) at #ARDD2026. Photos: agingpharma.org/photos2026
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Really wish caning 🦯 would be part of the sentence.
BREAKING: The first rioters and looters have been sentenced in France. The judges practically refuse to hand out prison sentences: 🔴 Toulouse – Ylan, 18 years old. Throwing a Molotov cocktail at police officer - Sentence: 12 months suspended + 140 hours of community service + deprivation of voting rights for 3 years. - Max. sentence: 10 years in prison 🔴 Lille – 3 men, including 2 illegal migrants. Arrested with bags filled with loot from Micromania and Calzedonia stores. - Sentence: 10 months in prison with custody warrant + 2-year territorial ban (for the 2 undocumented migrants). - Max. sentence: 5 years 🔴 Lille – Father of a family with a crowbar, attempted break-in at a store. - Sentence: 10 months in prison with custody warrant + 3-year ban on demonstrations. - Max. sentence: 7 years 🔴 Lille – 23-year-old man, launching fireworks at police - Sentence: 12 months under electronic monitoring + 140 hours of community service. - Max. sentence: 5 years 🔴 Reims – Sahel W., 19 years old. Looting a Carrefour - Sentence: 105 hours of community service. - Max. sentence: 7 years 🔴 Reims – Hugo M., 20 years old. Looting a Caviar boutique. - Sentence: 4 months under electronic monitoring. - Max. sentence: 7 years. 🔴 Rouen – Tunisian delivery driver, looting of a gold buyback shop (16,000€ worth of jewelry in his pockets). Repeat offender. - Sentence: 8 months in prison with custody warrant + revocation of 6 months suspended from a previous conviction. - Max. sentence: 14 years 🔴 Rouen – Anthony, homeless. Looting of the Courir boutique. Repeat offender. - Sentence: 6 months in prison + 6 suspended. - Max. sentence: 14 years 🔴 Rouen – 26-year-old unemployed man. Looting of Micromania. Repeat offender. - Sentence: 6 months under electronic monitoring. - Max. sentence: 14 years 🔴 Rouen – Nicolas, garbage collector, and Zakaria. Throwing projectiles at police and insults. - Sentence: 12 months under electronic monitoring. - Max. sentence: 5 years 🔴 Lyon – Mohamed, illegal migrant. Looting of Louis Vuitton boutique (6 wallets, 2 pairs of glasses, one pair of pants, one leather bag, and one fabric bag). - Sentence: 6 months in prison with custody warrant - Max. sentence: 7 years 🔴 Lyon – Cheima, 30-year-old woman. Looting of JD Sports store - Sentence: 8 months suspended. - Max. sentence: 7 years 🔴 Lyon – Sophia, 27 years old. Already 9 convictions including thefts. Looting of JD Sports store. - Sentence: 12 months under electronic monitoring. - Max. sentence: 14 years 🔴 Lyon – Adam, 19-y-old Swiss national. "Black bloc" from abroad. Arrested leaving a looted Monoprix + resistance - Sentence: 12 months suspended. - Max. sentence: 7 years 🔴 Perpignan – 20-y-old man, throwing a construction barrier at 2 police officers. - Sentence: 6 months under electronic monitoring - Max. sentence: 5 years 🔴 Perpignan – 21-y-old man. Throwing objects at police and vandalizing the city. Ski goggles, t-shirt as balaclava, and reinforced gloves. - Sentence: 10 months under electronic monitoring. - Max. sentence: 7 years 🔴 Perpignan – 22-y-old Amazon delivery driver, already one prior conviction. Scooter theft after demonstration with face concealment, in a group and break-in - Sentence: 8 months under electronic monitoring. - Max. sentence: 10 years 🔴 Limoges – 20-y-old woman. Looting in stores and at City Hall (later destroyed by fire) - Sentence: 6 months in prison with custody warrant + 18 suspended prob. - Max. sentence: 12 years 🔴 Pau – 43-y-old man. Throwing objects at police - Sentence: 6 months under electronic monitoring. - Max. sentence: 5 years 🔴 Nîmes – 24-y-old PE teacher. Throwing objects that injured a police man (3 days of leave). - Sentence: 18 months suspended prob. - Max. sentence: 5 years 🔴 Grenoble – 10 people. Looting Sentences: from 4 months suspended to 8 months served (served for 1 individual already convicted to suspended in June). Max. sentence: 7 years
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The real issue is that academic institutions are getting involved in personal lives. If you’re an adult you’re free to date whoever you want. Be it strangers, friends, or colleagues. As a grown up you shall reap the good as well as the bad of it. Any workplace policy that gets involved in someone’s love life is overstepping.
A Massachusetts jury has awarded biologist David Sabatini $6 million—plus interest—in damages in his defamation case against Kristin Knouse, a former colleague at the Whitehead Institute for Biomedical Research. The physician-scientist’s claims led one research institution to fire Sabatini and precipitated his resignations from Whitehead and the Massachusetts Institute of Technology, where he was a tenured faculty member. Read more: scim.ag/4jxig3b
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That may be very powerful for science!
China has selected its first group of young researchers to receive funding for up to 15 years, in one of the longest research grants on offer to scientists globally go.nature.com/4z4Q3pw
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"The most valuable thing in the industry is data on how the human body will respond." @impetusgrants' round on datasets enabling AI to reason about aging and disease will fund ~50 projects to proactively get this data ready for new models. >9/15M raised, tell your friends to donate so we can get going.
Dialectic 60: Patrick Hsu! @pdhsu & @arcinstitute are combining biology, engineering, and AI to turn a sci-fi future into reality. Patrick got expelled from college at 13, returned at 15, later worked on early CRISPR breakthroughs, and teamed up with @SKonermann & @patrickc to found Arc. He works 3 jobs: core investigator at Arc, professor at Stanford, and venture partner at @thrivecapital. For all his intensity and ambition, he carries a lightness and boldness that is contagious. We discuss: - why research is 99% failure and even your best ideas kind of suck - infinite games and speedrunning school - the reach of GLP-1s and power laws in biotech - what makes a good biologist - Arc’s bet on people over projects - lab robots that finally work - AI-designed organisms and new forms of life - why heart disease could go the way of infectious disease - bro science, peptides, and biofuturism - research taste in the age of AI Timestamps: (0:00) Opening Highlights (1:39) Intro: Patrick Hsu (4:29) Start: Boldness, Infinite Games, & Ambition (12:54) GLP-1s and Power Laws in Biotechnology (20:17) Expelled at 13 and Falling for Biology (25:51) What Makes a Good Biologist, Research Taste, and Biology's Data Challenges (37:58) The Arc Model: Full-Stack Science (52:01) Betting on People, Style, & Learning to Simplify (57:22) Perturbation, World Models, and Evo (1:03:27) Virtual Cell Models (1:09:56) Designing Life: From Stem Cells to Genome Writing (1:18:39) Testing, Bro Science, and Human Data (1:24:26) Can It Exist vs. Will It Exist: Science Meets Markets (1:29:59) Biofuturism: Interoception, Peptides, Muscle Modulation, Sleep, and New Forms of Life (1:43:47) Fun, Obsolescence, Going Slow, and the Future @dialecticpod 60: Patrick Hsu - Speedrunning the Infinite Game - is available on all platforms, including X. Links below.
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Actually a sensible proposal
Universities should really give alumni lifetime access to the library. We paid enough for tuition, the least you can do is let us keep reading.
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🤣
Senescent cells are like older people - they stop working and start shouting at their neighbors
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— This is the Amber Heard type who destroyed David Sabatini’s life and career. He may have gotten a big judgement against her from the jury, but he will likely have to fight to see even a penny of it. Meanwhile she gets to continue her illustrious career at MIT as a prof with her own lab. Disgusting.
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Instead of using European money for war efforts or lifestyle NGOs that embezzle money abroad Europe should spend 100 billion dollars on AI & data infrastructure.
Should Europe leave frontier AI to the Americans and the Chinese? The idea has gained ground in Europe. It is a fundamental mistake. Build or surrender: for now, the choice is still ours. Full article below.
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