@MicrobialCMMC

Collaborative Microbial Metabolite Center

 UC San Diego
cmmc.gnps2.org
Joined October 2024
  • Tweets60
  • Following88
  • Followers201
15Media
antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation academic.oup.com/nar/advance…
1
23
1
67
4,899
I went on a podcast again!! This time talking #cysticfibrosis, #coralreefs and all things science! Science is cool! @EddieBarstool and @BarstoolChief know this. So should you! @DogWalkBarstool youtu.be/5-yRUy_0kaI?si=_muX…

Biologist Explains One Of The Most Dangerous Diseases

On today's episode we are joined by a Michigan State biologist to t...

youtube.com
2
3
15
17,489
Thrilled to share our latest research out today in @Nature: “Microbial metabolite drives ageing-related clonal hematopoiesis via ALPK1” nature.com/articles/s41586-0…
21
49
7
265
37,654
It's out! It's out!! Our new paper on how conjugated bile acids affect gut inflammation is out in @NatureComms nature.com/articles/s41467-0…

Balance between bile acid conjugation and hydrolysis activity can alter outcomes of gut inflammation

Nature Communications - Here, the authors show that both host and microbially conjugated bile acids (Bas) can provide benefits to IBD patients, but this is dictated by a delicate balance between BA...

nature.com
1
8
27
949
One new article about #MicrobialCoCulture: "Vibralactone derivatives isolated from co-cultures of the basidiomycetes #Stereum hirsutum and #Boreostereum vibrans" link.springer.com/article/10…

Vibralactone derivatives isolated from co-cultures of the basidiomycetes Stereum hirsutum and...

Natural Products and Bioprospecting - The basidiomycetes Stereum hirsutum and Boreostereum vibrans are two fungi of the same genus. In this study, chemical investigation on the co-cultures...

link.springer.com
4
1
9
315
Have we finally discovered what a “normal” gut #microbiome looks like? Analysis of 45,454 microbiomes from 42 countries identified the Health-Associated Core Keystone (HACK) index, linking certain microbial profiles to lifestyle, disease, and health. cell.com/cell-reports/fullte…
6
64
6
211
15,455
Human Untargeted Metabolomics in High-Throughput Gut Microbiome Research: Ethanol vs Methanol | Analytical Chemistry pubs.acs.org/doi/10.1021/acs…

Human Untargeted Metabolomics in High-Throughput Gut Microbiome Research: Ethanol vs Methanol

Abstract. Untargeted metabolomics is frequently performed on human fecal samples in conjunction with sequencing to unravel the gut microbiome functionality

pubs.acs.org
4
19
897
The International Space Station has a unique and extreme microbial and chemical environment driven by use patterns: Cell cell.com/cell/fulltext/S0092…

The International Space Station has a unique and extreme microbial and chemical environment driven...

With long-term space travel and extraterrestrial habitation becoming feasible, understanding how space environmental exposures, microbial communities, and molecular profiles differ from Earth is...

cell.com
8
24
1,303
#CIMM2025 Speaker Spotlight: @lizljohnson’s research program focuses on understanding how lipids mediate diet-microbiome-host interactions with the goal of manipulating these interactions for the benefit of host health. Catch her presentation on Day 1!
1
2
205
"Metagenomic estimation of dietary intake from human stool" #GutMicrobiome nature.com/articles/s42255-0…

Metagenomic estimation of dietary intake from human stool

Nature Metabolism - Diener et al. present a method that allows the estimation of dietary intake from human stool by detecting food-derived DNA in faecal metagenomes.

nature.com
12
40
1,554
What if the gut microbiome drives sugar cravings? New research found the bacterium Bacteroides vulgatus was causally linked to intake of sugar, with pantothenic acid being the key metabolite involved: loom.ly/zce4bWU

Free fatty acid receptor 4 modulates dietary sugar preference via the gut microbiota

Nature Microbiology - Bacteroides vulgatus, a gut bacterium, promotes GLP-1 secretion through its metabolite, pantothenate, inhibiting sugar preference in mice.

nature.com
4
11
777
Check out our approach toward disciformycin and gulmirecin, spearheaded by @PeterRuehmann. @nyuchemistry @PennChemistry pubs.acs.org/doi/10.1021/acs…
3
16
135
6,578
EasyMetagenome: A user‐friendly and flexible pipeline for shotgun #metagenomic analysis in #microbiome research onlinelibrary.wiley.com/doi/… #Bioinformatics #pipeline @wileymicrobio @WileyBiomedical

EasyMetagenome: A user‐friendly and flexible pipeline for shotgun metagenomic analysis in microbi...

EasyMetagenome is a user-friendly shotgun metagenomics pipeline designed for comprehensive microbiome analysis, supporting quality control, host removal, read-based, assembly-based, binning, genome...

onlinelibrary.wiley.com
76
6
143
9,958
Akkermansia muciniphila is a promising target for managing obesity and type 2 diabetes However, this randomized trial reveals that the metabolic benefits of A. muciniphila supplementation could depend on its baseline intestinal levels: loom.ly/3z-rHwU
2
21
4
56
6,001
Systematic discovery of antibacterial and antifungal bacterial toxins | Nature Microbiology nature.com/articles/s41564-0…

Systematic discovery of antibacterial and antifungal bacterial toxins

Nature Microbiology - Genome sequence mining and computational analyses lead to the discovery and functional characterization of conserved bacterial toxins with activity against bacteria and fungi.

nature.com
12
70
3,970
How do diet and metabolism influence intestinal stem cells in health and disease, including tumorigenesis? Worth reading review in the January issue of @NatRevGastroHep: loom.ly/7tRwt_M

Dietary and metabolic effects on intestinal stem cells in health and disease

Nature Reviews Gastroenterology & Hepatology - In this Review, Shay and Yilmaz describe how diet and metabolism influence intestinal stem cells in health and disease, including tumorigenesis....

nature.com
14
2
33
2,375
Explore the role of bile acids made by the microbiome! Microbiome enthusiast Robert Quinn @Quinn_Labs is hosting a seminar on Feb. 14 from 9-10am at Fred Kavli Auditorium in Tata Hall: Microbial Bile Acid Conjugation as a New Mechanism of Host-Microbiome Crosstalk
1
2
6
463
Could microbiome-related products accelerate cellular senescence? New clues in @NatureAging: loom.ly/SmgoQzM

Gut microbial-derived phenylacetylglutamine accelerates host cellular senescence

Nature Aging - Yang et al. show an age-related increase in the microbial-derived metabolite phenylacetylglutamine that drives host cellular senescence by inducing DNA damage and mitochondrial...

nature.com
2
14
44
3,358
Great example of metabolites discovered with molecular networking.
Gary Siuzdak@kadzuis21 Jan 2025
Discovery of a family of bile acid-methylcysteamines @Nature @Cornell @group_Schroeder #activitymetabolomics A nuanced interplay between host and microbiota in regulating bile acid signaling pathways through FXR with a new target for metabolic disorders doi.org/10.1038/s41586-024-0…
1
13
1
54
3,581
Microbial secondary metabolites: advancements to accelerate discovery towards application nature.com/articles/s41579-0…

Microbial secondary metabolites: advancements to accelerate discovery towards application

Nature Reviews Microbiology - In this Review, Dinglasan and colleagues explore innovations that facilitate rapid microbial secondary metabolite discovery, focusing on recent techniques for the...

nature.com
1
5
200
Load more