In a new randomized controlled trial, skipping breakfast did not clearly worsen mood, sleepiness, or cognitive function in teenagers (13–15 y/o) when compared to regular low-GI breakfast (w/ or w/o nitrate supplementation).
nature.com/articles/s41538-0…
This crossover trial found that a vegan diet, but not a Mediterranean diet, substantially reduced people's estimated intake of advanced glycation end products (AGEs).
I think the jury is still out on the harms of AGEs, but interesting data nonetheless.
pubmed.ncbi.nlm.nih.gov/3917…
Morgan Pfiffner retweeted
🔎New study out from our Dartmouth team! 🔍
🧬Genetics interact with cue reactivity!🧬
onlinelibrary.wiley.com/doi/…
"Each FTO risk allele was associated with a 30% increase in [intake]... Food cue exposure exacerbated associations between the FTO variant with gummy candy [intake]."
In an article for @Examinecom I wrote about exercise-related energy compensation (ExEC), a phenomenon in which exercise burns fewer calories than expected.
examine.com/research-feed/st…
A new study analyzed a single dataset on red meat and mortality 1,208 different ways
In an article for @Examinecom, I discuss why researchers did this, what it tells us about epidemiology, and why it doesn't tell us much about red meat and health.
examine.com/research-feed/st…
I found another AI-generated garbage diagram in a scientific journal.
It’s entirely gibberish and features anatomically incorrect limbs with too many bones.
ncbi.nlm.nih.gov/pmc/article…
Follow-up: I’ve received notice that the journal is retracting this study, due to the above graphic and a number of concerning data irregularities pointed out by @MicrobiomDigest and @TKesteman on PubPeer.
In case anyone is interested, at @Examinecom we have a guide called “How to Read a Scientific Study”. It’s a great surface-level resource for catching study limitations that aren’t as obvious as AI-generated mutant leg bones.
examine.com/guides/how-to-re…
Most people who go on diets see weight loss plateau as time goes on. Could switching up your diet prevent this?
Maybe not. In a new study, diet-induced weight loss showed expected slowing, even as folks changed diets after 6 months (from low-fat to low-carb, or vice versa).
It's still possible that diet switching has some minor benefits (it may partially inhibit regain), but can't really say for sure until there's a similar RCT with a non-switching control group.
Reference: pubmed.ncbi.nlm.nih.gov/3868…
Does exercise help with depression? And which types help the most?
In my new article for @Examinecom I wrote about a curious meta-analysis on the topic: examine.com/research-feed/st…
I think this is objectively wrong (sorry Brady!).
There is extensive data that smoking increases mortality risk substantially more than sitting: pubmed.ncbi.nlm.nih.gov/3025…
"Sitting is the new smoking."
I think sitting is worse.
Based on some analyses, the mortality risk reduction associated with being physically active (-66%) is greater than the risk reduction associated with not smoking (-38%): sciencedirect.com/science/ar…
Sitting time and physical activity can be disentangled, as in the 45 and Up Study.
pubmed.ncbi.nlm.nih.gov/3102…
Is yogurt overrated for metabolic health?
In a new 16-week randomized controlled trial, yogurt was not clearly better than milk at improving health metrics like body fat, liver fat, blood pressure, blood lipids, or insulin resistance.
pubmed.ncbi.nlm.nih.gov/3823…
I’m excited to share my review of the book How Not to Diet!
HNTD makes a myriad of claims — with haphazard scientific accuracy — to rationalize an overly complicated diet that nonetheless seems conducive to weight loss and fairly healthy.
redpenreviews.org/reviews/ho…
New Review!
How Not to Diet: The Groundbreaking Science of Healthy, Permanent Weight Loss
By Michael Greger
Written by @MorganPfiffner
One of our most requested books. redpenreviews.org/reviews/ho…
In a new clinical trial, a Mediterranean diet led to impressive improvements in IBS symptoms (despite no difference in FODMAP or fiber intake).
I think this could be a big step forward for IBS management. Check out my article on study for @Examinecom.
examine.com/research-feed/st…
Credit to @FeliceJacka and colleagues at the @foodmoodcentre for this research.
In a new analysis from the Look-AHEAD trial, achieving remission of type 2 diabetes was associated with a 40% lower risk of CVD.
Remission was more likely in the lifestyle intervention (diet+exercise) group.
pubmed.ncbi.nlm.nih.gov/3823…
“Using the structured approach to assess concordance, 15 (19.0%) out of 79 analysed diet-disease outcome pairs were concordant.”
A cohort study with 59,033 women found that eating pan-fried red meat was associated with a lower risk of T2 diabetes...
...if participants cooked their meat in vegetable oil.
(sharing bc I found it interesting, but I wouldn't read too much into it)
ncbi.nlm.nih.gov/pmc/article…



















