The Mostoslavsky lab at Harvard & Mass General Cancer Center. We study chromatin, cancer, metabolism, DNA repair, PTMs et al. Tweets are from anyone in the lab!
Boston, MA, USA
Joined April 2018
- Tweets372
- Following477
- Followers1.3K
- Likes364
Mostoslavsky Lab retweeted
Thanks @HarvardGSAS for featuring my story going beyond the dogmas of life. Cannot wait to formally share with the world all the cool science we’re doing at the @MostoslavskyLab @MGHCancerCenter.
gsas.harvard.edu/news/beyond…
Mostoslavsky Lab retweeted
We’re happy to share our new study out today @NatureCellBio
We show that a chromatin factor, ZNF280A, is required for DNA double strand break repair, linking its absence to clinical features in 22q11.2 distal deletion syndrome.
@MostoslavskyLab
nature.com/articles/s41556-0…
Mostoslavsky Lab retweeted
Excited to share our new work on how DNAJB1-PRKACA drives cancer cell growth in Fibrolamellar Carcinoma.
@CD_AACR Thanks to all our collaborators and funding support. @FibroFoundation @AICF_nyc @DonaBertarelli @ForbeckForums @AlexLemonade
Now online in @CD_AACR: DNAJB1-PRKACA Drives #Fibrolamellar Liver Cancer via Impaired SIK Signaling & CRTC2/p300-mediated Transcriptional Reprogramming - by @IlariaG32, @DoransRing6012, Taranjit Gujral, Nabeel Bardeesy, et al. doi.org/10.1158/2159-8290.CD… @fredhutch @MGHCancerCenter
Mostoslavsky Lab retweeted
New Research: Subcellular one carbon metabolism in cancer, aging and epigenetics frontiersin.org/articles/10.… #FrontiersIn #Epigenetics #Epigenomics
Mostoslavsky Lab retweeted
New in @sciencemagazine! Our study reveals how mutant IDH1 inhibition activates tumor immunity by inducing dsDNA sensing. Read more: science.org/doi/10.1126/scie…
#CancerResearch #Cholangiocarcinoma #IDH1 1/n
Mostoslavsky Lab retweeted
FOR THE LOVE OF PURINES: We are truly excited to share our latest work @CellPressNews on mapping the routes of purine nucleotide synthesis in vivo-De novo and Salvage Purine Synthesis Pathways Across Tissues and Tumors.cell.com/cell/fulltext/S0092…
Mostoslavsky Lab retweeted
Massive effort by Christina Ferrer @MostoslavskyLab! I am so happy to see this piece of work finally published!
Online now!! Really thrilled to share our latest work identifying a novel driver of metastasis, Gstt1, @NatureCellBio. A huge effort lead by Christina Ferrer and an incredible team of collaborators!!
link.springer.com/article/10…
Mostoslavsky Lab retweeted
I’m thrilled to share that I will be joining the Boston University School of Medicine (@BUMedical) as an assistant professor! My lab will officially open on January 1, 2024, in the Department of Pathology and Laboratory Medicine.
Mostoslavsky Lab retweeted
I’m really excited to share a new study from our group @CellCellPress . Led by phenomenal postdoc Junbing Zhang, who uncovered a nucleus-to-mitochondria ROS sensing pathway that plays an important role in mediating chemoresistance. sciencedirect.com/science/ar…
Mostoslavsky Lab retweeted
Super excited for our first lab publication @CellMetabolism! Led by superstar postdocs Tommy and Maolin who uncover an unexpected role for NRF2 in regulating NADH-reductive stress in lung cancer. Check it out at: authors.elsevier.com/a/1gemY…
Mostoslavsky Lab retweeted
These are devastating news. He was not only a giant in science, but the most incredible human being. Every conversation with him left me inspired. David, you will be missed. A great loss.
Mostoslavsky Lab retweeted
REVIEW | R Mostoslavsky, R Boon & G Silveira (@harvardmed) explore how nuclear #metabolism regulates compartamentalization, #epigenetics & cell physiology.
#TBT 🔙
nature.com/articles/s42255-0…
Mostoslavsky Lab retweeted
This review outlines mechanistic insights of DNA repair and how these are used to treat age-related disease & cancer:
▪️PARP inhibitors vs breast & ovarian cancer
▪️PARPi acquired drug resistance
▪️Alternatives to PARPi
🔓buff.ly/3QI6VvN
#DNArepair #DNAdamageResponse
Mostoslavsky Lab retweeted
Don’t miss keynote speakers Joel Moss @nih_nhlbi and @LadurnerAndreas at our NAD+ Metabolism and Signaling Conference! Explore emerging research and network with your peers. Organizer @MostoslavskyLab and his co-organizers want to see you there! bit.ly/3DyaW0f #NBCSRC22
Mostoslavsky Lab retweeted
Reconnect with your colleagues IN PERSON at the NAD + Metabolism and Signaling Conference, 6/25-30 #NBCSRC22
More info & agenda: bit.ly/3uNcgtw
Abstract Deadline is 4 weeks away! Students get $150 off reg $.
Keynotes: Joel Moss, MD, PhD &Andreas Ladurner, PhD
ALT Launched in 2011, this FASEB SRC Series convenes biannually in alternate venues between the USA and Europe. It explores the latest findings in NAD+ metabolism and signaling as they relate to human health, disease, and medicine and provides a forum to engage scientists from multiple fields and disciplines. The overarching theme is to explore the latest findings in NAD+ metabolism and signaling as they relate to human health, disease, and medicine.
Mostoslavsky Lab retweeted
📢 We have an exciting new nanocourse in May!
Cancer Metabolism: The Metabolomics Perspective
Keynote speakers @KanarekNaama, @alex_toker, @MostoslavskyLab and @nada_kalaany!
More info & registration bit.ly/CancerMetabolismNanoc…
Mostoslavsky Lab retweeted
Our last work together with @MostoslavskyLab is finally out! Really thankful to all people involved @MGHCancerCenter @harvardmed @fpoirccs and the members of @CSebastianLab @fpoirccs @UniBarcelona @IBUB_UB @PCB_UB.
nature.com/articles/s41467-0…
Mostoslavsky Lab retweeted
More coverage of the Cell Reports study we collaborated on, lead by @MostoslavskyLab
#LiveCellMicroscopy #DNARepair @DalMedSchool
💠 Story in the Chronicle Herald | SaltWire saltwire.com/atlantic-canada…
