Scientist at @PrimeMedicine. Formerly at @liugroup of @Harvard and @broadinstitute

Joined December 2020
Efficient prime editing in two-cell mouse embryos using PEmbryo go.nature.com/483v6g9
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Excited to share our review on prime genome editing! Enormous thank you to everyone who has developed and innovated this technology!
Today we share in @NatureRevGenet a review of prime editing for precise and versatile genome manipulation. The review covers current prime editing strategies, limitations, recent developments, and applications, including work from 148 publications. 1/5 drive.google.com/file/d/1K4e…
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A testament to how fast this field moves, we unfortunately missed a couple PE papers that were published after our final revision: nature.com/articles/s41587-0…, nature.com/articles/s41467-0…, nature.com/articles/s41467-0…, and cell.com/molecular-therapy-f…
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Today we share in @NatureRevGenet a review of prime editing for precise and versatile genome manipulation. The review covers current prime editing strategies, limitations, recent developments, and applications, including work from 148 publications. 1/5 drive.google.com/file/d/1K4e…
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Today we share in @NatureProtocols detailed strategy and experimental procedures for designing and executing prime editing (and twinPE) experiments in mammalian cells. Congrats Jordan, @AlexanderASousa, Peyton, and @PeterJ_Chen for this thorough analysis. drive.google.com/file/d/12oI…
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Peter Chen retweeted
In the latest issue! PE4 and PE5 are efficient and precise prime editing systems with enhanced efficiency of substitution, small insertion, and small deletion prime edits #geneediting #primeediting #sciencetwitter @davidrliu @Harvard @broadinstitute bit.ly/2ZsB5gX
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Our work developing Repair-seq, a platform for studying #DNArepair processes, and its application to double-strand breaks is out today @CellCellPress. Alongside, we release seq.repair, a portal for exploring many, many DNA repair phenotypes! cell.com/cell/fulltext/S0092…
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Today we report in @CellCellPress our new PE4max and PE5max prime editing systems that we first presented at @CSHLmeetings in August. 1/12 drive.google.com/file/d/1IGi…
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