@Piotraz1

Geneticist interested in (meiotic) recombination and impact of chromatin structure on DNA functions

 Poznan, Poland
dgb.amu.edu.pl
Joined July 2016
  • Tweets737
  • Following794
  • Followers1.5K
65Media
‼️A new story from our lab!🙌 We show that SNI1, a component of the SMC5/6 complex, acts as a temperature-dependent brake on class II crossovers, helping shape where genetic exchange occurs in Arabidopsis. Huge effort by Alex made it happen🙏
Alexandre Pelé@ARM_PeleSep 23
1/2 My very first post on X—and what better occasion than the publication of our paper in @NaturePlants! 🌱 We identify SNI1 as the first plant gene linking temperature to meiotic recombination, generating genetic diversity that may help plants adapt. nature.com/articles/s41477-0…
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Now also with a Nature Plants Research Briefing! 🌱 A short overview of how SNI1/NSE5 links temperature to meiotic crossover control in Arabidopsis.
Nature Plants@NaturePlantsSep 24
New OA Article: "SNI1/NSE5 is a cold-sensitive brake on class II crossovers in Arabidopsis" rdcu.be/P1VqD9W4RvQa With Research Briefing: "SNI1 governs how temperature reshapes crossovers and genetic diversity" rdcu.be/1ZSG6fvWCPJa
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A very cool story showing, once again, that nature will find a way…
André Marques@marques_et_alSep 16
Out today in Nature: sex without crossovers. Rhynchospora tenuis makes pollen, fertilises and sets seed, yet 0 crossovers in 10,997 pollen nuclei. Chromosome drive and ~87% seed abortion rebuild the mother's genotype, so the offspring are clones. doi.org/10.1038/s41586-026-1…
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Plant Meiosis Meeting 2026 is over! 🌿🧬 Over 90 people, three days of great science, discussions and new ideas in Poznań. Huge thanks to Maja @SzymanskaLejman, our organising team, Neil Hunter, all speakers and everyone who joined us! See you at the next PMM! 🎉
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Piotr Ziolkowski retweeted
Ian Henderson@hendersiJul 25
CRISPR-mediated centromere fission generates neochromosomes with distorted meiotic inheritance in Arabidopsis biorxiv.org/content/10.64898… new preprint from us - includes changing the Arabidopsis karyotype from 5 -> 6 chromosomes using Cas9 & outcomes of 5/6 chromosome hybrid meiosis
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Nature Plants@NaturePlantsJul 26
New OA Article: "The deSUMOylase SPF2 and the cohesin regulators SGO2 and CTF18 suppress crossovers near centromeres" rdcu.be/fvZuX With News & Views: "Crossovers break new ground" rdcu.be/fvZu6
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⏳ Last days to register for the Plant Meiosis Meeting! Join us in Poznań for PMM 2026, with invited speakers Neil Hunter, Mathilde Grelon, André Marquez and Kyuha Choi. Raphaël Mercier, Chris Morgan, Stefan Heckmann and many others also confirmed. pmm.amu.edu.pl
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Piotr Ziolkowski retweeted
Karel Riha@karlrihaMay 13
Heat stress induces the formation of unreduced male gametes by targeting translation in Arabidopsis meiocytes academic.oup.com/plcell/arti… I am glad to take part in this story by Cedric Schindfessel and Danny Geelen

Heat stress induces the formation of unreduced male gametes by targeting translation in Arabidopsis...

TAM regulates the translation of meiotic cell cycle genes under heat stress to prevent premature meiotic exit and ensure ploidy consistency in the natural

academic.oup.com
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Piotr Ziolkowski retweeted
IMBB AMU Poznań@UAM_IBMiBApr 15
Big news! 🥳 Andrzej Zielezinski (@a_zielezinski, @UAM_IBMiB) together with @AdamGudys, @cnotred, and @sdeorowicz present FAMSA2, enabling ultra-scale multiple protein sequence alignment. Now in Nature Biotechnology! nature.com/articles/s41587-0…

Fast and accurate multiple-protein-sequence alignment at scale with FAMSA2

Nature Biotechnology - FAMSA2 accurately aligns millions of protein sequences at high speed.

nature.com
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Our new experimental evolution study across 30+ locations using the plant Arabidopsis thaliana —— we direct "see" adaptation and extinction to different climates at the genetic as it happens! Read it in Science dx.doi.org/10.1126/science.a… @UCBerkeley @hhmi_science
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📣Registration for the Plant Meiosis Meeting is now open‼️The website and preliminary program are live; abstract submission coming soon. Book accommodation early due to major trade fairs in Poznań! See you in Poznań! 🌱 pmm.amu.edu.pl
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Our paper about NUP1/NUP136 and its meiotic role is now available at @GeneticsGSA! @MarinaMtzGcia @MonicaPradillo xitter.cf/GeneticsGSA/status/203…
Genetics Society of America@GeneticsGSAMar 18
A new study in #GENETICS from @MonicaPradillo and colleagues uncovers a key role for the plant-specific nuclear basket nucleoporin NUP1/NUP136 in chromosomal interactions and crossover formation in #Arabidopsis. buff.ly/seSFKgY
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A quick correction: the post below should say H3K4me3, not H3K9me3. 👇
Piotr Ziolkowski@Piotraz1Mar 13
📣Our paper is finally out!🤩 We found that local modification of H3K9me3 using CRISPR/dCas9 at hotspots changes crossover activity, bringing us closer to targeted recombination in plants.🌱 Huge thanks to @SzymanskaLejman, Wojtek, Ania, and Karolina!💪 science.org/doi/10.1126/scia…

Modifying meiotic recombination by targeting chromatin regulators to crossover hotspots in Arabid...

Targeting chromatin modifiers to DNA hotspots reveals causal link between histone marks, transcription, and meiotic recombination.

science.org
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📣Our paper is finally out!🤩 We found that local modification of H3K9me3 using CRISPR/dCas9 at hotspots changes crossover activity, bringing us closer to targeted recombination in plants.🌱 Huge thanks to @SzymanskaLejman, Wojtek, Ania, and Karolina!💪 science.org/doi/10.1126/scia…

Modifying meiotic recombination by targeting chromatin regulators to crossover hotspots in Arabid...

Targeting chromatin modifiers to DNA hotspots reveals causal link between histone marks, transcription, and meiotic recombination.

science.org
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IMBB AMU Poznań@UAM_IBMiBFeb 5
Michal Gdula @michal_gdula group leader at the @UAM_IBMiB is saerching for a postdoc to work on the epigenetics of pancreatic cancer within colaborative OPUS-LAP project funded by @NCN_PL and @dfg_public - reach out! #3Dgenome #cancer #pancreas
Michal Gdula #StandWithUkraine 🇺🇦@michal_gdulaFeb 5
We’re recruiting! Three-year, fully funded #postdoc opportunity: pancreatic cancer #epigenetics & potential new treatments (funded by @NCN_PL & @dfg_public). Collaboration with @AkisPapantonis, University of Göttingen (OPUS-LAP). See the ad & contact me! drive.google.com/file/d/1vrF…
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André Marques@marques_et_alJan 27
A new extreme of meiotic evolution: ✔️ no crossovers ✔️ no gene conversion ✔️ normal meiosis & fertility Sex mimics clonality without becoming asexual, in the holocentric multicellular eukaryote 𝘙𝘩𝘺𝘯𝘤𝘩𝘰𝘴𝘱𝘰𝘳𝘢 𝘵𝘦𝘯𝘶𝘪𝘴. more about it: biorxiv.org/content/10.64898…
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📣Plant Meiosis Meeting is back for its second edition‼️ Save the date: 9–11 September 2026, Poznań, Poland🌱 More details coming soon🤩
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CRISPR-Cas–mediated heritable chromosome fusions in Arabidopsis | Science science.org/doi/10.1126/scie… So cool!!!🤩

CRISPR-Cas–mediated heritable chromosome fusions in Arabidopsis

The genome of Arabidopsis thaliana consists of 10 chromosomes. By inducing CRISPR-Cas–mediated breaks at subcentromeric and subtelomeric sequences, we fused entire chromosome arms, obtaining two...

science.org
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Piotr Ziolkowski retweeted
james Higgins@jamesdhiggins7620 Nov 2025
Our latest paper on SCEP3 suggests that CO interference is required to reduce numbers of COs for individual pairs to <3 so that there enough for all chromosomes to maintain the obligate CO nature.com/articles/s41477-0…

SCEP3 initiates synapsis and implements crossover interference in Arabidopsis

Nature Plants - SCEP3 is a new synaptonemal complex protein that prevents clustering of crossovers during meiosis in Arabidopsis, so that every pair of homologous chromosomes receives at least one...

nature.com
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🌿🔍Paper alert‼️ A fantastic study from James Higgins’ group on SCEP3 – a newly identified component of the synaptonemal complex in plants! Happy that our team could be part of this! 😄🧬
Nature Plants@NaturePlants19 Nov 2025
New OA Article: "SCEP3 initiates synapsis and implements crossover interference in Arabidopsis" rdcu.be/eQKqW A new synaptonemal complex protein; prevents clustering of crossovers during meiosis, so every pair of chromosomes receives at least one ‘obligate’ crossover.
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