collectively ran by the Pruneda lab, MMI, Oregon Health & Science University @ohsummi | our views are our own
Portland, Oregon
Joined September 2019
- Tweets36
- Following121
- Followers155
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Pruneda Lab retweeted
Great talk by Rachel Lacoursiere from @PrunedaLab regarding bacterial enzymes to understand non canonical ubiquitination #EMBOubiquitin24
Pruneda Lab retweeted
Excited to share this work from former @PrunedaLab superstar @camgroberts! Cam tackled the challenge of identifying #ubiquitin regulators secreted by pathogenic bacteria, and found an entirely new type of E3 ligase that regulates P. aeruginosa virulence!
biorxiv.org/content/10.1101/…
Pruneda Lab retweeted
Fantastic to have @jnpruneda @PrunedaLab from @OHSUSOM visiting giving a seminar on his team’s exciting work on how pathogenic bacteria use nifty effector proteins to hijack the ubiquitin system and avoid the host response. Real pleasure to have you at @DTUbioengineer, Jonathan.
As #RareDiseaseDay rapidly approaches, please consider contributing to our collaboration with @RaidenScience to study a rare pediatric disorder.
Our Annual Run4Raiden 5K is back! ⚡️🦓
This year's fundraising goal is to raise $60K to continue our UBA5 drug repurposing program. 🧬🔬
Sign Up or Donate Today: run4raiden.raiselysite.com
@OHSUNews @jnpruneda @RuthJeanNapier
Pruneda Lab retweeted
Please consider supporting @RaidenScience! We’re determined to find a way to help children afflicted with this rare #ubiquitin-related disease.
Our Annual Run4Raiden 5K is back! ⚡️🦓
This year's fundraising goal is to raise $60K to continue our UBA5 drug repurposing program. 🧬🔬
Sign Up or Donate Today: run4raiden.raiselysite.com
@OHSUNews @jnpruneda @RuthJeanNapier
Pruneda Lab retweeted
Pleased to share the final version of this work on UBA5, available at @eLife.
doi.org/10.7554/eLife.89891.…
New @PrunedaLab research direction: a #RareDisease of the #ubiquitin-like modifier UFM1. This sets the stage for understanding and, one day, helping kids with UBA5 disease. Inspiring to work with @RuthJeanNapier and @RaidenScience on this important topic.
doi.org/10.7554/eLife.89891.…
Pruneda Lab retweeted
Excited to share the final product of this work, now available at @MolecularCell. Extremely proud of @tylergfranklin for this and many other achievements during his thesis work!
sciencedirect.com/science/ar…
What can bacteria teach us about #ubiquitin? A lot!
In our latest preprint, @tylergfranklin set out to understand how secreted bacterial ligases catalyze ubiquitin modifications during infection. What he found will surprise you!
biorxiv.org/content/10.1101/…
Great job @tylergfranklin!
Yesterday the @PrunedaLab produced its first PhD scientist! Congratulations @tylergfranklin on five years of incredible growth and science, capped by a fantastic thesis defense. Added bonus: his paper was accepted on the same day! Keep an eye on this one, he’ll do great things.
Pruneda Lab retweeted
New preprint identifying shared and distinct mechanisms of inactivation of the #ubiquitin E1 enzyme #UBA1 across different diseases #VEXAS #SMA #lungcancer doi.org/10.1101/2023.10.10.5…
Thanks to David Beck @nyulangone, @kyliejwalters and all contributors for a great collaboration!
Pruneda Lab retweeted
Excited to share our new review on bacterial effectors that follow or break the "rules" of #ubiquitin signaling. Always a pleasure to work with @camgroberts and @tylergfranklin!
embopress.org/doi/abs/10.152…
Pruneda Lab retweeted
Bacteria can counter noncanonical lipid ubiquitination with a #ubiquitin esterase! Fantastic collaboration with @ThurstonLab and @CMBI_Szczesna, with @r_lacoursiere driving our side of the project using some amazing tools built by the Geurink lab.
Excited to share our preprint on how a cytosolic bacteria evades LPS ubiquitylation and antibacterial autophagy through an effector with esterase activity. Led by @CMBI_Szczesna in the lab @ImperialInfect @CBRB_Imperial with superb collaborator @jnpruneda researchsquare.com/article/r…
Pruneda Lab retweeted
Excited to share our preprint on how a cytosolic bacteria evades LPS ubiquitylation and antibacterial autophagy through an effector with esterase activity. Led by @CMBI_Szczesna in the lab @ImperialInfect @CBRB_Imperial with superb collaborator @jnpruneda researchsquare.com/article/r…
Pruneda Lab retweeted
What can bacteria teach us about #ubiquitin? A lot!
In our latest preprint, @tylergfranklin set out to understand how secreted bacterial ligases catalyze ubiquitin modifications during infection. What he found will surprise you!
biorxiv.org/content/10.1101/…
Pruneda Lab retweeted
Happy to share that this work is now online in its peer-reviewed form at @MolecularCell. Huge thanks to our peer reviewers for challenging us, and to my co-authors for rising to meet this challenge. Check out the final product! sciencedirect.com/science/ar…
I’m very excited to share our latest work, in which we identify, characterize, and apply a Legionella deubiquitinase that targets host Lys6-linked #ubiquitin signals with extreme precision. biorxiv.org/content/10.1101/…
Great job Tyler!
Grad student 1st time presenter @tylergfranklin impressed us all @FASEBorg Ub with cool Ub chain engineering; shown here with his PhD advisor @jnpruneda
Pruneda Lab retweeted
I’m very excited to share our latest work, in which we identify, characterize, and apply a Legionella deubiquitinase that targets host Lys6-linked #ubiquitin signals with extreme precision. biorxiv.org/content/10.1101/…
Pruneda Lab retweeted
Proud to 🚀 the #RaidenScienceFoundation including Nobel Laureate Dr. Ciechanovar, @UMassChan @PrunedaLab @StJude and @BCMFromtheLabs
..who will together develop a treatment for #UBA5, an ultra-rare neurodegenerative disease.
raidenscience.org/
Congratulations @camgroberts!
Ever tried to give a 3-minute research presentation? It isn't easy! @PrunedaLab member @camgroberts gave a fantastic flash talk at #UKcellmicro2021 this week and even won a prize! Congratulations to Cam and thank you to the organizers for such a great meeting!
Pruneda Lab retweeted
Ever tried to give a 3-minute research presentation? It isn't easy! @PrunedaLab member @camgroberts gave a fantastic flash talk at #UKcellmicro2021 this week and even won a prize! Congratulations to Cam and thank you to the organizers for such a great meeting!
Of course Justine did a fantastic job, we were never DUBious! So proud of @justinevnguyen!
Huge congratulations to @PrunedaLab member @justinevnguyen for skillfully defending her Master’s thesis on bacterial deubiquitinases today! Well done Justine!