Group based @BabrahamInst in Cambridge. Interested in #phosphatases. She/her. Now on BSky - see you over there.
Cambridge, UK
Joined April 2016
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Hayley Sharpe retweeted
Check out our newly updated proteostasisuk.co.uk/. If you are working in the UK on #proteostasis, please consider listing your lab and filling out the survey.
Hayley Sharpe retweeted
Calling teachers! Register now for the Babraham Institute Sixth Form Conference 2024 – a special event where young people get to experience a taste of a real-life academic conference.
Full details: bit.ly/BabrahamSFC
ALT Sixth form conference 2024 theme: proteostasis
Hayley Sharpe retweeted
👋Job alert! We are recruiting 2 group leaders working in the field of cancer cell biology to join our centre at @QMBCI @QMUL. Come and join us 🤩
👉Get in touch if you have any questions!
🚨 We have two exciting group leader opportunities for scholars with a passion for cancer cell biology: one Reader and one Senior Lecturer position. Join us!
➡ Reader: bit.ly/3Mfk3bd
➡ Senior Lecturer: bit.ly/3MgTanf
📆 30.09.24
Hayley Sharpe retweeted
Deadline for applications for this potdoc postion in our group is the end of August. Please get in touch if you would like additional information.
Link: tinyurl.com/57ea9p3f
We are looking for a Postdoc to investigate novel genes that regulate insulin-stimulated glucose transport (tinyurl.com/ycarykzh). MRC-funded collaboration with O'Rahilly (@StephenORahilly) @IMS_MRL & Langenberg groups (QMUL).
Please RT.
Link: tinyurl.com/57ea9p3f
Hayley Sharpe retweeted
Did you see the latest research from @KatieYoung1995
@Sharpe_Lab: new findings on the role of PTPRK in tissue repair and cancer?
💡Including the extent of its function via non-catalytic signalling mechanisms
babraham.ac.uk/news/2024/07/…
@J_Cell_Sci
ALT Image shows three immunofluorescent images of mouse colons stained for nuclei (DAPI;blue) and cellular junctions (ZO1; green). Text reads: News - Research sheds light on the role of PTPRK in tissue repair and cancer
Hayley Sharpe retweeted
Katherine Young @KatieYoung1995, Hayley Sharpe @Sharpe_Lab @BabrahamInst and colleagues discover that PTPRK promotes intestinal repair and catalysis-independent tumour suppression.
Highlight: journals.biologists.com/jcs/…
Article: journals.biologists.com/jcs/…
ALT Heatmap showing differential gene expression between WT and PTPRK KO HT29 cells that was rescued by reintroduction of PTPRK and/or PTPRK.RQ. Graph of Gene ontology (GO) analysis of genes suppressed by PTPRK showing an overrepresentation of genes annotated with the biological processes ‘epithelial to mesenchymal transition’ and ‘mesenchymal cell differentiation’, as well as Wnt signalling. Amongst genes that were upregulated by PTPRK, GO analysis revealed overrepresentation of genes annotated with the terms ‘negative regulation of epithelial cell proliferation’ and ‘regulation of cell migration’. Also, graph showing a ∼2-fold upregulation of Ptprk in organoids treated with TGFβ1 in the RNA-seq data from two out of three published studies. Finally, a graph showing that organoids mutant for P53 and KRas harbouring the Notch1 ICD showed significantly reduced levels of PTPRK.
Hayley Sharpe retweeted
📢 #postdoc role available! 📢
Application deadline is
🌟16th July 2024🌟
Please get in touch if you're interested! kcl.ac.uk/jobs/087846-resear…
Hayley Sharpe retweeted
Speeding through the French countryside on the TGV en route to #EMBOpseudoenzyme near Girona.
Hayley Sharpe retweeted
Programme for 2024 Thiol-Redox Gordon Conference now online. Exciting array of topics and speakers with 16 talks still to be selected from abstracts grc.org/thiol-based-redox-re… Great opportunity for Early Career Researchers to present their work in the GRS too.grc.org/thiol-based-redox-re…
Hayley Sharpe retweeted
I can't wait to hear more of the groundbreaking new Redox research that will be presented at grc.org/thiol-based-redox-re… Still a few places left, but you need to apply/reigster ASAP -especially if you would like to join as one of 16 selected speakers! Also grc.org/thiol-based-redox-re…
Programme for Thiol-Redox GRC now online grc.org/thiol-based-redox-re… Lots of talks to be selected from abstracts -so get your applications in and join the friendly thiol-redox community for exciting scientific discussions by the Mediterranean!
Hayley Sharpe retweeted
Have you secured your spot at next week's talk from Prof Clare Bryant as part of our Babraham Distinguished Lecture Series? Clare is Professor of Innate Immunity at the Departments of Medicine and Veterinary Medicine in the University of Cambridge.
Info - ow.ly/9WaT50RyrNk
Hayley Sharpe retweeted
We’re hiring! We’re looking for a Reviews Editor to work across our journals (@Dev_journal, @J_Cell_Sci, @J_Exp_Biol, @DMM_Journal). If you’ve got excellent communication skills and a broad interest in science, this is a job for you!
Location: Cambridge UK
biologists.com/about-us/work…
Hayley Sharpe retweeted
Interested in antibody responses? Interested in joining our team? We will move to the Babraham Institute, Cambridge very soon, and currently have three vacancies. Two postdocs babrahaminstitute.livevacanc… and a research assistant babrahaminstitute.livevacanc…
Hayley Sharpe retweeted
Only a couple of days left! Pls apply if interested and RT!
65K gene pairs screened across multiple cell lines, 2 tissues - data waiting for you to interpret and make important discoveries! collaboration with @OpenTargets @Garnettlab OT Validation lab and industry partners!
Hayley Sharpe retweeted
Less than a month to go until the inaugural @UK_proteostasis Conference @BabrahamInst!
But don't worry, there's still time to get your ticket ow.ly/Avwy50R7iAX
Hayley Sharpe retweeted
🚨Still time to register for this #UKRedoxNetwork half-day meeting on April 17th - free to attend!🚨
Join us in person or online:
UKRedoxNetwork2024.eventbrit…
Join us for this #UKRedoxNetwork meeting on April 17th!
Excellent opportunity to engage with the UK #redox community and to present your research (poster session and elevated talks for ECRs)
Free registration:
UKRedoxNetwork2024.eventbrit…
Hayley Sharpe retweeted
@IvaskaLab offered the @ERC_Research AdG! Excited to pursue #BorderControl to gain fundamental understanding of metastasis in collab with @guijacquemet @EPeuhu @ValerioIzzi @PekkaRuusuvuori @BioscienceTurku @InFLAMES_Health @UniTurku @pipsa_saharinen @WickstromLab @SalmiLab
Hayley Sharpe retweeted
It's clear there are barriers in academia that disproportionately impact minoritised researchers.
That's why we've launched new funding for researchers of Black, Bangladeshi and Pakistani heritage in the UK. @ShomariLW explains ⤵️
Hayley Sharpe retweeted
It is great to see a cultivating #diversity session @MicrobioSoc #microbio24 covering some awesome incentives to make microbiolgy more inclusive and support everyone to do their best science #EDI
Hayley Sharpe retweeted
An interview with Sandra Schmid @slschmid_CZB – Chief Scientific Officer of the @czbiohub
We hear about Sandy’s career, her role as an advocate for women in science, and her recent transition to the Chan Zuckerberg Biohub #CZBiohubSF.
journals.biologists.com/jcs/…
ALT Sandra Schmid