Bioinformatician | Founder of MyGen Informatics
Wageningen, Netherlands
Joined March 2018
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Happy to receive the doctorate with designation 'cum laude' from @WUR under the great mentorship of @dolfweijers. Thank you Dolf and everyone else for your support. Open access to my thesis: doi.org/10.18174/511001
Sumanth Mutte retweeted
Out now in @MolecularCell: Cyanobacterial Argonautes and Cas4 family nucleases cooperate to interfere with invading DNA
cell.com/molecular-cell/full…
Most long-A pAgos interfere with invading DNA solo. Why then are cyanobacterial pAgos co-encoded with a Cas4-like protein?
A 🧵
Sumanth Mutte retweeted
A pangenome reference of wild and cultivated rice @Nature
nature.com/articles/s41586-0…
Happy to have worked together with @BarendsePatrick @pilar_bobadilla and @DCSwarts great supervision... (One of) The last manuscripts from my tenure at @WUR and the first one from my company @MyGenInfo ...
🔥New paper! 🔥
Distribution of bacterial DNA repair proteins and their co-occurrence with immune systems (cell.com/cell-reports/fullte…)
It started with a simple question: Are certain prokaryotic immune systems always (or never) encoded with specific DNA repair proteins?...
Sumanth Mutte retweeted
Auxin and tryptophan trigger common responses in the streptophyte alga Penium margaritaceum biorxiv.org/cgi/content/shor… #biorxiv_plants
Interesting and thoughtful!
There aren't enough smart people in biology doing something boring
owlposting.com/p/there-arent…
new argument piece
i often meet a lot of founders in biology pursuing really crazy, revolutionary ideas. i love them! but i wish there were more people pursuing the boring ideas
🧵
Sumanth Mutte retweeted
It is my great pleasure to announce ggPlantmap (github.com/leonardojo/ggPlan…), an open-source R package to create ggplot maps from plant images. Now, you can create beautiful plant heatmaps to be visualized and modified in a R coding environment.
Sumanth Mutte retweeted
We are recruiting!📢 A postdoc position is available in our lab @WUR ! Please take a look at the details in the attached flyer! Pls repost!
Sumanth Mutte retweeted
itol.toolkit accelerates working with iTOL (Interactive Tree Of Life) by an automated generation of annotation files academic.oup.com/bioinformat…
Sumanth Mutte retweeted
Just found out about the awesome @naturemethods' #PointsOfSignificance column on statistics for biologists that explains key statistical & experimental design concepts by @MKrzywinski & Naomi Altman
Check out all 50 articles mkweb.bcgsc.ca/pointsofsigni…
ALT http://mkweb.bcgsc.ca/pointsofsignificance/bibliography.mhtml#projecthome
Sumanth Mutte retweeted
Happy to share our new @bioRxiv pre-print: we provide a comprehensive profile of plant hormones in all streptophyte #algae lineages and some other as outgroups.
Find out more: biorxiv.org/content/10.1101/…
🧵[1/10]:
@PetrasekLab #phytohormones #evolution
Sumanth Mutte retweeted
Looking for #Bioinformatics courses on #GitHub? 🧐 You're in luck! 🍀@choup @P_Palagi and I from @ISBSIB have created #Glittr (glittr.org): a webapp that helps you find and compare awesome training materials. 🎉
How does it work? And how can you join us? Read on! 👇
Sumanth Mutte retweeted
And another chapter done! Learn about build automation using {targets}
If you’re interested in upping your data science game and build reproducible analytical pipelines, give my book a read, it’s free:
raps-with-r.dev
Comments more than welcome! #RStats #DataScience
Sumanth Mutte retweeted
It's been a while since this work started as the main project in Asier's PhD. Long story short is that DELLAs have not changed that much during evolution, which is impressive, but functional divergence was partly driven by their interactors and cis element evolution.
New Letter "DELLA functions evolved by rewiring of associated transcriptional networks" rdcu.be/c7vVN
DELLA modulate dozens of TFs through direct physical interaction. This ability is conserved in land plants but with different biological effects in different lineages.
Great work! Congratulations Karthi @murukarthickj and the whole team!
Marking a milestone in #plant #genomics!!!
An amazing team of scientists around the globe unraveled the giant #fababean genome (~ 13 Gb), which is now out @Nature ..Huge congrats to all authors!!! #plantprotein @LeibnizIPK @LeibnizWGL
nature.com/articles/s41586-0…
Congratulations, @vera_gorelova 👏
The Plant Cell welcomes 2023 Assistant Features Editors! @ASPB #WeAreASPB doi.org/10.1093/plcell/koac3…
A new dimension to phytohormone biology. Myself and Jasper developed a simple shiny app to explore the phosphoproteome data: weijerslab.shinyapps.io/AuxP…. Appreciate any feedback and suggestions. GitHub: github.com/WeijersLab/AuxPho….
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Latest from our lab @AndreKuhn8 @dolfweijers
A RAF-like kinase mediates a deeply conserved, ultra-rapid auxin response biorxiv.org/cgi/content/shor… #biorxiv_plants
Sumanth Mutte retweeted
A long look at short prokaryotic Argonautes!
Given the recent advances in the field, we (@BalwinaK, @SumanthMutte and me) have written a review highlighting the exciting discoveries and (many) remaining questions.
View our review here (free link!):
authors.elsevier.com/a/1g7hM…
Excellent piece of work, Shub. Fundamental yet solid experiments and clean results, well done! Congratulations to all!
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Sumanth Mutte retweeted
Single-sequence protein structure prediction using a language model and deep learning go.nature.com/3fCqoAu
