he/him/his | G5 Graduate Student @ChemistryMIT | working with @KiesslingGroup and @shaleklab | alumni @iiserkol | Multi-omic TechDev

Kolkata, India
Joined June 2017
Ankit Basak retweeted
Thrilled to share my freshly "baked" Baker lab paper. We took a bottom-up approach to designing transcriptional regulators. Instead of relying on natural activation domains, we designed compact proteins that recruit specific cofactors. Activators for now, repressors to come!
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Ankit Basak retweeted
Avengers assemble: 1 year BakerLab + NVIDIA GenAIR = 🔥 rfd4-proteina.org Presenting RFD4-Proteina, our latest protein design model, significantly better and faster than everything we compared against, both in silico and in the lab! 1/30
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Ankit Basak retweeted
Congratulations to Henri B. Kagan and Kenso Soai for the 2026 Nobel Prize in Chemistry, "for the discovery of non-linear effects and autocatalysis in asymmetric organic synthesis." And this story has a boy from Pune in it.... Kagan's half began in 1986. He showed that a catalyst carrying only a small excess of one handedness can produce a product with a much larger excess. The small imbalance does not stay small. Soai's half came in 1995: a reaction that makes more of itself, and prefers its own mirror image. By 2003 he reported a version that produced only one hand. A tiny imbalance, amplified until one mirror image dominates. Extraordinary, and for about 25 years the machinery behind it resisted explanation. Many models were proposed. None stuck. Then a boy from Pune decided the unexplained part was the only part worth doing. Soumitra Athavale grew up in Pune, studied chemistry and biology at IISER Pune, and went to the University of Illinois in 2014 for a PhD in molecular and cell biology. But he could not let the Soai mystery go. So he started cold emailing organic chemistry profs, asking to work on this one puzzle. Professor Scott Denmark met him, said yes, and found the money. In 2020, Athavale was 1st author of the Nature Chemistry paper with Adam Simon, Kendall Houk and Denmark that gave the reaction the structural picture that stuck: a homochiral tetrameric catalyst, working almost like an enzyme, explaining the amplification the field had chased for a quarter century. Denmark says students like Soumitra come along once or twice in an academic career. The man who found the reaction is Japanese. The man who helped explain it was born in Pune. Congratulations again to Kagan and Soai. And here is to Soumitra Athavale, the Indian who went looking for the mystery everyone else had learned to live with.
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Ankit Basak retweeted
Preference for US citizens with no prior experience in India.
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Ankit Basak retweeted
I really like what David Baker saying here: “For the first time, the speed of AI is beginning to match the experimental power of synthetic biology”.. let’s see what can scale faster! Electron vs biology. newsroom.uw.edu/news-release…
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Ankit Basak retweeted
Meet Prof. Subhajit Bandyopadhyay, the IISER Kolkata chemist who mentored India's Chemistry Olympiad team to its best-ever finish this July. He studied at the University of Burdwan for his bachelor's, then IIT Kanpur for his master's, before earning his PhD under Prof. Reginald Mitchell at the University of Victoria in Canada. He went on to postdoc with Prof. Ron Breslow at Columbia University and spent a year at Cambridge under Prof. Florian Hollfelder before joining IISER Kolkata as an Assistant Professor. Since then, he's picked up 4 Best Teacher Awards from IISER Kolkata's own student community, become a Fellow of the Royal Society of Chemistry, and earned an Honorary Membership of the American Chemical Society. This July, as Head Mentor, he guided India's 4-student team through the 58th IChO in Tashkent, Uzbekistan. All 4 came home with gold. India tied for Rank 1 with China and Vietnam, its best result in 27 appearances at the competition. Mentor who spent 27 years building the platform his students needed just 5 days in Tashkent to stand on.
Another Golden Sweep by India as our Chemistry team bags 4 Gold medals securing Rank #1 (jointly with China, Vietnam, and Individual Participant (Russia)) at the 58th International Chemistry Olympiad, Uzbekistan (icho2026.uz). 1/5
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Ankit Basak retweeted
The future of science is already in preprints. The next cancer treatment. The next vaccine. The next disease mechanism. But as more science is published, the signal gets harder to find. QED Score makes emerging science actionable earlier. the-one-percent.qedscience.c…
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Deep-STARmap and Deep-RIBOmap are imaging-based sequencing platforms for profiling transcriptional and translational activity in thick tissue blocks. @WangXiaoLab @xsui98 nature.com/articles/s41592-0…
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Delighted to see Martins Otikovs' titanic effort to provide a contemporary view on spatiotemporally encoded (SPEN) MRI. Thanks Martins and Zhiyong, both for this effort but foremost for the science and ideas we shared over the last decade. See below for more:
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Congratulations to Stephanie Yiu, Ankit Basak, Ye Won Cho, Laura Kiessling, Chia-Yu Chen, Alex K. Shalek, David Kim & Sizun Jiang for winning the KI Images People's Choice Award! Their image, "Periodontal Petals", shows how cells organize to maintain oral health.
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Thank you! It feels amazing to have our collaborative work on periodontitis being recognized for the KI Images People's Choice Award. @kochinstitute @ChemistryMIT @MIT_IMES @dental_harvard @BIDMChealth @harvardmed @shaleklab @KiesslingGroup @SizunJ
Congratulations to Stephanie Yiu, Ankit Basak, Ye Won Cho, Laura Kiessling, Chia-Yu Chen, Alex K. Shalek, David Kim & Sizun Jiang for winning the KI Images People's Choice Award! Their image, "Periodontal Petals", shows how cells organize to maintain oral health.
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Ankit Basak retweeted
Huge cancer breakthrough! mRNA vaccine (similar to COVID vaccine tech) shows stunning results against pancreatic cancer! 75% of responsive patients STILL cancer-free at 3 yr, normally 80% recur. Could revolutionize treatment for one of deadliest cancers! Funded in part by @NIH
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Ankit Basak retweeted
A scientist who successfully treated her own breast cancer by injecting the tumour with lab-grown viruses has sparked discussion about the ethics of self-experimentation go.nature.com/3NXqzEq
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Ever wished you could zoom in more? @W_Shiwei co-advised by @ChemicalBiology and @eboyden3 expands a hydrogel up to 20x original size with brain tissue inside. This tool will enable nanoscale-resolution imaging without laborious iterations. nature.com/articles/s41592-0…
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Scalable, compressed phenotypic screening using pooled perturbations go.nature.com/3ZV58uX
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Ankit Basak retweeted
🚀 Excited to share our new publication in @NatureBiotech! We explore scalable strategies for phenotypic screening using innovative methods with to address the challenges when the number of candidates is simply too large. Check out the details tinyurl.com/5f8vjhpp! (1/10)
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Our Compressed Screening paper is out! So grateful and honored to have worked with an amazing team of individuals 🙏 ya'll are the best 💯
🚀 Excited to share our new publication in @NatureBiotech! We explore scalable strategies for phenotypic screening using innovative methods with to address the challenges when the number of candidates is simply too large. Check out the details tinyurl.com/5f8vjhpp! (1/10)
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A collaboration between researchers at @MIT and @GeorgiaTech has revealed a new strategy for enabling immune system mobilization against cancer cells. The produces exactly the type of anti-tumor immunity needed to function as a tumor vaccine. chemistry.mit.edu/chemistry-…
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