@biomemphys

Biomembranes - Immunology - Immune Domains - Plasma Membranes - Scale Bridging - Free Energy

 Erlangen, Deutschland
biomemphys.nat.fau.de
Joined November 2013
  • Tweets184
  • Following377
  • Followers451
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Böckmann Lab retweeted
Leonhard Möckl@LMoeckl28 Aug 2025
Excited to see this one out in JACS! We analyzed how molecular interactions lead to self-organization of glycolipids down to microseconds and nanometer spatiotemporal scales. Amazing collaboration with @SandoghdarLab, @biomemphys, and Thisbe Lindhorst! pubs.acs.org/doi/abs/10.1021…

Bottom-up Investigation of Spatiotemporal Glycocalyx Dynamics with Interferometric Scattering...

Abstract. Over recent decades, the glycocalyx, an extracellular organelle composed of a multitude of glycolipids, glycoproteins, proteoglycans, and glycoRN

pubs.acs.org
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Böckmann Lab retweeted
Peeref@Peeref128 Aug 2025
Newly published in @J_A_C_S “Bottom-up Investigation of Spatiotemporal Glycocalyx Dynamics with Interferometric Scattering Microscopy” by Brunner et al. pubs.acs.org/doi/10.1021/jac… @LMoeckl @SandoghdarLab @biomemphys
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🚀 Biologie, Physik & Mathematik – alles in einem Studium! 🎓 Integrated Life Sciences an der FAU: Von Zellbiologie & Programmieren bis zu Big-Data-Analyse und moderner Mikroskopie. 📅 Bewerben bis 15. August auf campo.fau.de – sichere dir deinen Studienplatz!
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Hörsaalquiz der Biologie Fachschaft @UniFAU
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Böckmann Lab retweeted
Ricarda Lang@Ricarda_Lang5 Mar 2025
Gebt den Sondierungen noch zwei Wochen und Markus Söder baut uns allen kiffend ne Wärmepumpe ein.
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🌟 Ph.D./Postdoc in Computational Membrane Biophysics 🌟 Join our team at @UniFAU to study Lugdunin, a unique antimicrobial peptide, using cutting-edge simulations. Collaborate with experts, and advance antimicrobial science. 🌟 #membranes #AMP
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Details at biomemphys.nat.fau.de/jobs/
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New study alert, published in PNAS! Our team revisits lipid nanoparticle composition and structure, challenging coarse-grained simulation approaches that may mask crucial pH-driven phase transitions. Discover how setups may bias LNP structures #LNP @UniFAU
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pnas.org/doi/10.1073/pnas.24… @MTrollmann

Revisiting lipid nanoparticle composition and structure: A critical take on simulation approaches |...

Revisiting lipid nanoparticle composition and structure: A critical take on simulation approaches

pnas.org
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Böckmann Lab retweeted
FAU Erlangen-Nbg@UniFAU10 Jan 2025
Zeit, neue Wege zu gehen: Wir beenden unsere Aktivitäten auf X. Bleiben Sie mit uns im Dialog – auf unseren anderen Kanälen. -- Time to move on: We are ending our activities on X. Stay connected with us through our other channels. #eXit #WissXit #SciXit #ByeByeX #quitx
Illustration einer Person, die ein "X" in eine Mülltonne wirft. Auf dem Boden ein toter Vogel, im Hintergrund die Logos der Plattformen Bluesky und Mastodon.

ALT Illustration einer Person, die ein "X" in eine Mülltonne wirft. Auf dem Boden ein toter Vogel, im Hintergrund die Logos der Plattformen Bluesky und Mastodon.

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Interested in #clathrin? Our new paper with @sciFelixFrey on the cooperative curvature model for clathrin-mediated endocytosis is now out in Physical Review E: doi.org/10.1103/PhysRevE.110… Here a short thread to explain the main ideas ... (1/5)
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Böckmann Lab retweeted
Leonhard Möckl@LMoeckl10 Dec 2024
A big step for better ways to look at small things: Automated discovery of experimental designs in SR microscopy! A wonderful collaborative effort with @carlardrguez96, @soerenarlt, and @MarioKrenn6240. Paper: rdcu.be/d2107 PR: tinyurl.com/3a5237xu
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🚨 Preprint Alert! 🚨 Check out our new book chapter on Constant-pH MD Simulations of Lipids! Learn how to use CpHMD simulations to study pH-dependent behavior of aminolipids in LNPs. 💊🧬 #membranes #LNP @MTrollmann @UniFAU biorxiv.org/cgi/content/shor…
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👉 Please have a look at the accompanying paper too! biorxiv.org/content/10.1101/…

Mechanistic Insight into pH-Driven Phase Transition of Lipid Nanoparticles

Lipid nanoparticles (LNPs) are essential delivery vehicles in mRNA-based vaccines, with their functionality largely governed by aminolipids. At low pH, protonated aminolipids facilitate efficient...

biorxiv.org
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🌟 Ph.D./Postdoc in Computational Membrane Biophysics 🌟 Join our team at @UniFAU to study Lugdunin, a unique antimicrobial peptide, using cutting-edge simulations. Collaborate with experts, and advance antimicrobial science. 📩 Apply: [email protected] #membranes #AMP
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Details at biomemphys.nat.fau.de/jobs/
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🚨 Preprint Alert 🚨pH-induced phase transitions in lipid nanoparticle (LNP) formulations are crucial for LNP function – but not all settings in MD simulations allow to observe these transitions... #membranes #LNP @MTrollmann @UniFAU arxiv.org/abs/2412.02731
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Preprint alert! 🚨 "To be protonated or not to be protonated? That is the question! 🤔 In our latest study, we used constant-pH simulations to uncover the dynamic (de)protonation of ionizable aminolipids in Lipid Nanoparticles (LNPs). #membranes @MTrollmann @UniFAU
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🧪 With hundreds of titratable sites, we explored how these key components behave in the BioNTech & Pfizer LNP formulation. Our findings reveal a fascinating pKa shift by more than 3 units and resolve a position-dependent protonation of aminolipids. biorxiv.org/cgi/content/shor…
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Very grateful for research funding granted by #DFG to study antimicrobial peptide Lugdunin's selectivity for gram-positive bacteria. Thrilled to continue collaboration with Steinem Lab, Göttingen. Insights could pave the way for new strategies against resistant infections.@UniFAU
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